The global Aptamers market size is expected to be worth around US$ 18.91 billion by 2030, according to a new report by Vision Research Reports.
The global Aptamers market size was valued at US$ 823.6 million in 2020 and is anticipated to grow at a CAGR of 38.2% during forecast period 2021 to 2030.
Advancements in aptamer development technologies, increasing R&D, and rising number of companies investing in this market are some of the key driving factors responsible for the growth of this market.
Numerous advantages offered by these small molecules in comparison to established antibodies have also led to higher demand for these molecules across a diverse range of medical applications. They are chemically synthesized, which eliminates batch-to-batch variation and demands less time for development. Along with this, continuous advancement in technologies is expected to stimulate growth. Integrated DNA Technologies, Inc. introduced a next-generation product, Ultramers that contain aptamer template length up to 200 bases. According to the company, this new product will be apt for biotechnology applications such as gene and clone construction. Thus, new developments in this field are expected to boost usage of these products in different application areas, thereby driving market growth.
Furthermore, growing incidence of life-threatening diseases such as cancer has directed many companies to introduce new & effective detection assays based on aptamer therapy. In March 2017, Aptamer Sciences, Inc. unveiled multiprotein biomarker assay by using this technology for the detection of lung cancer. This kit is designed for early detection and diagnosis of non-small cell lung cancer by identifying a suitable biomarker. Such types of new product launches are expected to trigger the acceptance of these therapies, leading to market growth to a great extent. In addition, increasing number of small-scale startups, government organizations, rising number of products under clinical investigation, and growing number of academic research laboratories investigating the potential of aptamers are anticipated to support future growth of this market.
In contrast, many aptamers have failed to meet the requisite safety and efficacy standards in clinical studies. Thus, companies have to terminate the clinical investigation during late-stage clinical studies. This factor is likely to affect growth of this market negatively. In addition, other factors such as low awareness about these technologies in middle- & low-income countries and inadequate regulatory structure may hamper the overall growth.
the nucleic acid segment held the majority of the revenue share, which accounts for around 80% of the global market. Better thermodynamic and chemical stability of nucleic acid aptamers compared to peptide therapeutics have helped this segment capture large revenue share. In addition, R&D of nucleic acid aptamers is constantly increasing for the purpose of therapeutic indication.
Companies such as Ophthotech Corporation, NOXXON Pharma, and others are currently investigating nucleic acid-based aptamers for various purposes. For example, Ophthotech Corporation’s Fovista, a chemically synthesized nucleic acid aptamer, is currently under clinical investigation. This drug has shown promising safety and efficacy results in phase 2b clinical studies. Approval of such types of nucleic acid products may support the growth of this segment during the future period.
In contrast, the peptide type is considered to be a low revenue generating segment. However, many companies have started investing in the peptide aptamers market, which provides a healthy platform for the growth of this segment. For instance, Aptagen, LLC developed Peptimers, which are peptide-based aptamers. Unlike nucleic acid-based aptamers, Peptimers are composed of amino acid building blocks, which increase the affinity of ligands. Such product launches support constant growth of this type segment.
Out of various applications, the diagnostics segment dominated the market in 2020. Growing demand for aptamers for biomarker discovery, molecular imaging, and other diagnostic purposes has contributed to the growth of this application segment. In addition, many research studies have identified the potential of this molecule for the diagnosis of various chronic diseases.
An article by the Brazilian Journal of Infectious Diseases (December 2016) detailed the use of DNA/RNA aptamers for the efficient diagnosis of parasitic diseases. This fact has made aptamer a natural choice amongst hospital diagnosticians and researchers for diagnostic purposes, which is expected to drive growth.
Therapeutic applications may witness rapid growth over the coming years and are projected to grow with a CAGR of 30.6%. This molecule exhibits several advantages as therapeutic moiety compared to antibody drugs. Unlike antibody drugs, this chemically synthesized molecule binds 1,000 times stronger and offers higher stability to the target proteins. Thus, many companies are researching on the role of aptamers for disease treatment, such as neurodegenerative, cardiovascular, HIV, and various cancers. This is expected to make aptamer a driving force in the future of medicine.
Developed regions, North America & Europe, dominated the global market and captured more than 79% share during 2020. North America is considered to be the highest revenue generating market with an approximate revenue share of 51% in 2016. The growth of the North America market can be majorly attributed to the constant technological advancements in technologies and increasing number of companies coupled with rising R&D activities in this area. The U.S. is the largest market in the region owing to favorable government initiatives and increasing number of research laboratories.
Aptamer Group; Aptamer Sciences, Inc.; Base Pair Biotechnologies, Inc.; NOXXON Pharma; SomaLogic, Inc.; Ophthotech Corporation; and many others Eli Lilly & Company, Merck & Co., Inc., and others
Research and Developments
The Aptamers market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.
The report provides size (in terms of volume and value) of Aptamers market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.
This report focuses on the global Aptamers market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Aptamers market development in United States, Europe and China.
It is pertinent to consider that in a volatile global economy, we haven’t just conducted Aptamers market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.
In terms of production side, this report researches the Aptamers capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.
In terms of consumption side, this report focuses on the consumption of Aptamers by regions (countries) and application.
Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Aptamers market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.
With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Aptamers market companies.
Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Aptamers market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.
The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.
Overall, this is an in-depth research report specifically for the Aptamers industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.
The Aptamers market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Aptamers market.
Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Aptamers market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.
Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Aptamers market. These factors have benefited the growth of the global market for Aptamers. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.
New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Aptamers. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).
In this study, the years considered to estimate the market size of Aptamers are as follows:
Reasons to Purchase this Report:
- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.
This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.
Market Size Estimation
Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).
The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.
Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.
All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.
Market Breakdown and Data Triangulation
After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.
Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.
In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.
The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.
The study objectives of this report are:
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