Bone Graft Substitutes Market Size, Share, Trends, Growth, Consumption, Revenue, Company Analysis and Forecast 2020-2027

Published Date : Nov 2020 | No. of Pages : 200 Pages | Category : Healthcare

The global bone graft substitutes market size surpassed at US$ 3 Bn in 2019 and to reach US$ 3.7 billion by 2027.

The global bone graft substitutes market is expected to grow at a moderate CAGR of 3.2% during the forecast period 2020 to 2027. The market growth will be primarily driven by surge in the number of spinal fusion surgeries worldwide, increase in focus on research and development, onset of new, cost-efficient, and highly effective bone graft substitute materials, and rise in adoption of bone graft substitutes in the regenerative medicine field. Market players should focus on expanding their product portfolio and continue to focus on utilizing materials with improved quality, properties, and functionalities.

Bone grafts have been used for bone regeneration, structure restoration, and pain relief for decades. Conventionally, autografts were used for bone grafting, wherein a patient’s own bone was used as a graft. Autologous bone grafts are considered gold standard for bone transplant. However, usage of autologous bone grafts involves the risk of infection transfer during surgical procedures at both tissue harvesting and transplant sites. This could result in delayed wound healing and prolonged hospital stay. In terms of product, the global bone graft substitutes market has been classified into allografts, synthetic bone grafts, and xenografts. The allografts segment has been bifurcated into demineralized bone matrix (DBM) and others. The allografts segment captured the largest market share in 2019 and the trend is anticipated to continue during the forecast period. The allografts segment is expected to be driven by ready availability of allografts in various shapes and sizes that can be processed in various forms such as chips and others as per the requirement. The synthetic bone grafts segment is likely to be driven by increase in geriatric population with oral health problems and rise in number of bone graft surgeries performed in the past few years.

Based on material, the global bone grafts substitutes market has been categorized into ceramic-based, polymer-based, growth factor-based, cell-based, and others. The ceramic-based segment has been split into calcium phosphate, calcium sulfate, and others. The polymer-based segment has been segregated into polylactides, polyglycolides, polyurethanes, and others. In terms of application, the global bone graft substitutes market has been classified into craniomaxillofacial, dental, foot & ankle, joint reconstruction, spinal fusion, long bones, and others.

Based on end user, the global bone grafts substitutes market has been divided into hospitals, clinics, and academic & research institutes. The hospitals segment held major share of the global market in 2019.

Prominent Regions

North America held a major share of the global bone graft substitutes market in 2019. Technological advancements and rise in the need of treatment of complex bone diseases are the key factors driving the market in the region. Asia Pacific is projected to capture significant share of the global bone graft substitutes market during the forecast period. The growth of the bone graft substitutes market in the region can be attributed to rise in prevalence of chronic bone diseases, patient awareness about use of bone graft substitutes for treatment of orthopedic conditions, healthcare expenditure in emerging economies, and number of orthopedic & spinal fusion surgeries.

Prominent players operating in the global bone graft substitutes market include

  • DePuy Synthes
  • RTI Surgical, Inc.
  • Integra LifeSciences
  • NuVasive, Inc.
  • Stryker 
  • Wright Medical Group N.V.
  • Xtant Medical 
  • Zimmer Biomet 
  • Baxter
  • Medtronic

Market Segmentation

Bone Graft Substitutes Market, by Product

  • Allografts
    • Demineralized Bone Matrix (DBM)
    • Others
  • Synthetic Bone Graft
  • Xenograft
  • Autograft
  • Others

Bone Graft Substitutes Market, by Material

  • Ceramic-based
    • Calcium Phosphate
    • Calcium Sulfate
  • Polymer-based
    • Polylactides
    • Polyglycolides
    • Polyurethanes
    • Others
  • Growth Factor-based
  • Cell-based
  • Others

Bone Graft Substitutes Market, by Application

  • Craniomaxillofacial
  • Dental
  • Foot & Ankle
  • Joint Reconstruction
  • Spinal Fusion
  • Long Bones
  • Others

Bone Graft Substitutes Market, by Product by Application

  • Allografts
    • Craniomaxillofacial
    • Dental
    • Foot & Ankle
    • Joint Reconstruction
    • Spinal Fusion
    • Long Bones
    • Others
  • Synthetic Bone Graft
    • Craniomaxillofacial
    • Dental
    • Foot & Ankle
    • Joint Reconstruction
    • Spinal Fusion
    • Long Bones
    • Others
  • Xenograft
    • Craniomaxillofacial
    • Dental
    • Foot & Ankle
    • Joint Reconstruction
    • Spinal Fusion
    • Long Bones
    • Others
  • Autograft+
    • Craniomaxillofacial
    • Dental
    • Foot & Ankle
    • Joint Reconstruction
    • Spinal Fusion
    • Long Bones
    • Others
  • Others
    • Craniomaxillofacial
    • Dental
    • Foot & Ankle
    • Joint Reconstruction
    • Spinal Fusion
    • Long Bones
    • Others

Bone Graft Substitutes Market, by End User

  • Hospitals
  • Clinics
  • Academic & Research Institutes

Bone Graft Substitutes Market, by Product by End User

  • Synthetic Bone Graft
    • Hospitals
    • Ambulatory Care Centers
    • Academic & Research Institutes
  • Xenograft
    • Hospitals
    • Ambulatory Care Centers
    • Academic & Research Institutes
  • Autograft
    • Hospitals
    • Ambulatory Care Centers
    • Academic & Research Institutes
  • Others
    • Hospitals
    • Ambulatory Care Centers
    • Academic & Research Institutes

Bone Graft Substitutes Market, by Region

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • U.K.
    • France
    • Italy
    • Spain
    • Rest of Europe
  • Asia Pacific     
    • China
    • India
    • Japan
    • Australia & New Zealand
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East & Africa

Scope of the Report

VRR’s report on the global bone graft substitutes market studies the past as well as current growth trends and opportunities to gain valuable insights of the market during the forecast period from 2020 to 2030. The report provides the revenue of the global bone graft substitutes market for the period from 2018 to 2030, considering 2020 as the base year and 2030 as the forecast year. The report also provides the compound annual growth rate (CAGR %) for the global bone graft substitutes market for the same period.

The report has been prepared after extensive research. Primary research involved bulk of research efforts, wherein analysts conducted interviews with market leaders and opinion makers. Secondary research involved referring to key players’ product literature, annual reports, press releases, and relevant documents to understand the global bone graft substitutes market.

Secondary research also included Internet sources and statistical data from government agencies, websites, and trade associations. Analysts have also employed a combination of top-down and bottom-up approaches to study various phenomena in the global bone graft substitutes market.

The report includes an elaborate executive summary, along with a snapshot of the growth pattern of various market segments included in the scope of the study. Furthermore, the report sheds light on the changing competition dynamics in the global bone graft substitutes market. These indices serve as valuable tools for existing market players as well as new players interested in entering the global bone graft substitutes market. The next section of the report highlights the USPs, which include technological advancement, key industry events (mergers, acquisitions, collaborations, partnerships, etc.), number of bone grafting procedures 2019, pricing analysis for 2019, autologous product advancement, and COVID-19 pandemic impact on bone graft substitutes industry.

The report delves into the competition landscape of the global bone graft substitutes market. Key players operating in the global bone graft substitutes market have been identified and each one of these has been profiled for distinguishing business attributes. Company overview, financial standings, recent developments, and SWOT are some of the attributes of players operating in the global bone graft substitutes market profiled in this report.

Key Questions Answered in Bone Graft Substitutes Market Report

  1. What are the major drivers, restraints, and opportunities in the global bone graft substitutes market?
  2. What is the revenue share projection of key segments of the global bone graft substitutes market during the forecast period?
  3. Which segment is likely to lead the global bone graft substitutes market in terms of revenue between 2020 and 2030?
  4. How mergers & acquisitions among players are widening the scope of the global bone graft substitutes market?
  5. What is the market position of different companies operating in the global bone graft substitutes market?

Research Objectives and Research Approach

The comprehensive report on the global bone graft substitutes market begins with an overview of the market, followed by the scope and objectives of the study. The report provides detailed explanation of objectives of this study and health care compliances laid down by accredited agencies in the purview of research in the global bone graft substitutes market. It is followed by market introduction, market dynamics, and an overview of the global bone graft substitutes market, which includes VRR’s analysis of market drivers, restraints, and trends pertaining to the global bone graft substitutes market. Furthermore, Y-o-Y growth analysis with elaborate insights has been provided in order to understand the Y-o-Y growth trend of the global bone graft substitutes market.

For reading comprehensibility, the report has been compiled in a chapter-wise layout, with each section further divided into smaller ones. The entire report comprises an exhaustive collection of graphs and tables that are appropriately interspersed in the entire compilation. Pictorial representation of actual and projected values of key segments is visually appealing to readers. This also allows comparison of market shares of key segments in the past and at the end of the forecast period.

The report segments the global bone graft substitutes market in terms of product, material, application, end user, and region. Key segments under each criterion have been studied at length and the market share for each segment by the end of 2030 has been provided. Such valuable insights enable market stakeholders in making informed business decisions for investments in the global bone graft substitutes market.


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