Cell Lysis & Disruption Market (By Technique: Reagent-based, Physical Disruption; By Product: Instruments, Reagents & Consumables, Enzymes, Kits & Reagents; By Cell Type: Mammalian cells, Bacterial cells, Yeast/Algae/Fungi, Plant cells; By Application: Protein Isolation, Downstream Processing, Cell Organelle Isolation, Nucleic Acid Isolation; By End-Use: Academic & Research Institutes, Hospitals & Diagnostic Labs, Cell Banks, Pharmaceutical & Biotechnology Companies) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

Published Date : Aug 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Cell Lysis & Disruption market size is expected to be worth around US$ 10.70 billion by 2030, according to a new report by Vision Research Reports.

The global Cell Lysis & Disruption market size was valued at US$ 13.30 billion in 2020 and is anticipated to grow at a CAGR of 10.35% during forecast period 2021 to 2030.

Growth Factors

Demand for cell lysis & disruption is driven by the immense growth of the biotechnology sector globally. This is majorly due to the high adoption of biotech processes in the pharmaceutical, agricultural, and bio-services industries.

Technological developments in procedures involved to release cellular organelles have paved the way for higher adoption of cell disruption methods. As retrieval and purification of biopharmaceuticals involve cell disruption, a rise in demand for biopharma would lead to the subsequent growth of the market. In addition, advancements in the field of proteomics, metabolomics, and personalized medicine are expected to fuel progressive changes in this sector. However, the high cost of equipment coupled with the dearth of skilled professionals is expected to restrain revenue generation to a certain extent.

Report Highlights

Physical disruption methods were traditionally adopted by major players operating in this space for the extraction of intracellular contents. However, the adoption of these methods has relatively decreased currently owing to the requirement for expensive and cumbersome equipment. Owing to the presence of variability in the apparatus, physical disruption methods are difficult to repeat, thus reducing their market penetration

On the contrary, reagent-based methods do not destroy the biological activity of the final products, are mild, and ideally suited for laboratory samples. The mentioned facts make them a suitable choice for laboratory usage, consequently leading to their dominance in terms of market share in 2020, and over the forecast period.

Reagents and consumables accounted for the largest share in revenue in 2020, out of which dominated the cell lysis & disruption market and are expected to grow at a faster pace in the coming years as well. Factors attributing to the estimated share include an application for the selective product release, and controlled lysis as these provide biological specificity to the process. Owing to the enzyme specificity, different kits and enzymes are available for bacterial, plant, yeast, and mammalian samples. These enzymes are commercially available in a variety of forms. Major brands include but are not limited to Alfa Aesar, Millipore Sigma, MP Biochemicals LLC, Pierce Biotechnology Inc, and Promega Corporation.

The mammalian cells segment accounted for the largest share in 2020 and is expected to remain dominant throughout the forecast period. This is because mammalian culture systems are extensively used during the bio-manufacturing of viral vaccines, therapeutic proteins, and other recombinant products. Also, the adoption of 3D mammalian culture systems in stem cell and cancer research is anticipated to boost segment growth.

As the efficiency of reagents varies with the type of cell used, key companies have developed reagents that work specifically on mammalian cells. For instance, Merck Millipore provides a range of mammalian lysis reagents that are utilized for the preparation of mammalian phosphorylated, cytosolic, and nuclear proteins. Some of these products are CytoBuster protein extraction reagent, NucBuster protein extraction kit, PhosphoSafe extraction reagent, and ProteoExtract kits.

These methods find wide applications in protein isolation and downstream processing of biopharmaceuticals. The major application areas of protein isolation include, western blotting, and immunoprecipitation. Demand for efficient and rapid lysis techniques that can extract proteins with minimal breakdown or oxidation is expected to fuel segment growth. Viscosity, which is resultant of the cell debris and genomic contamination is another challenge that needs to be addressed, pronouncing research in this segment. The development of advanced bioprocessing reagents and equipment that can readily complement the established disruption procedures are anticipated to propel growth in the market.

North America accounted for the largest revenue share of more than 40.0% in 2020. Various government initiatives in the U.S. and Canada that support molecular biology research, precision medicine, and cancer research are expected to impel the cell lysis and disruption market growth in this region. High private, as well as public, investments in target therapeutics and novel drug discovery for the treatment of various complicated and rare diseases are anticipated to drive the demand further. However, Asia Pacific is poised to witness the fastest growth over the forecast period owing to the growing interest of key companies in emerging markets to reap higher profits.

Key Players

Thermo Fisher Scientific, Inc.; Merck KGaA; F. Hoffmann-La Roche Ltd; Qiagen NV; Becton Dickinson & Company (BD); Danaher Corporation; Bio-Rad Laboratories, Inc.; Miltenyi Biotec GmbH; Claremont BioSolutions, LLC; Microfluidics International Corporation; Parr Instrument Company; BioVision, Inc.; Covaris, Inc.; and Qsonica LLC. 

Market Segmentation

  • Technique Outlook
    • Reagent-based
      • Detergent
      • Enzymatic
    • Physical Disruption
      • Mechanical Homogenization
      • Ultrasonic Homogenization
      • Pressure Homogenization
      • Temperature Treatments
  • Product Outlook 
    • Instruments
      • High-Pressure Homogenizers
      • Sonicator
      • French Press
      • Microfluidizer
      • Bead Mill
      • Other Instruments
    • Reagents & Consumables
    • Enzymes
      • Detergent Solutions
      • Ionic detergent
      • Nonionic detergent
      • Zwitterionic detergent
    • Kits & Reagents
  • Cell Type Outlook 
    • Mammalian cells
    • Bacterial cells
    • Yeast/Algae/Fungi
    • Plant cells
  • Application Outlook
    • Protein Isolation
    • Downstream Processing
    • Cell Organelle Isolation
    • Nucleic Acid Isolation
  • End-Use Outlook 
    • Academic & Research Institutes
    • Hospitals & Diagnostic Labs
    • Cell Banks
    • Pharmaceutical & Biotechnology Companies
  • Regional Outlook 
    • North America
      • The U.S.
      • Canada
    • Europe
      • Germany
      • U.K.
    • Asia Pacific
      • Japan
      • China
      • India
    • Latin America
      • Brazil
      • Mexico
    • MEA
      • South Africa
      • Saudi Arabia

The Cell Lysis & Disruption market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Cell Lysis & Disruption market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Cell Lysis & Disruption market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Cell Lysis & Disruption market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Cell Lysis & Disruption market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Cell Lysis & Disruption capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Cell Lysis & Disruption by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Cell Lysis & Disruption market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Cell Lysis & Disruption market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Cell Lysis & Disruption market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Cell Lysis & Disruption industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Cell Lysis & Disruption market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Cell Lysis & Disruption market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Cell Lysis & Disruption market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Cell Lysis & Disruption market. These factors have benefited the growth of the global market for Cell Lysis & Disruption. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Cell Lysis & Disruption. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Cell Lysis & Disruption are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2020
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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