Continuous Renal Replacement Therapy Market Size, Share, Growth, Trends, Consumption, Revenue, Company Analysis, Regional Insights and Forecast 2021-2028

Published Date : Nov 2020 | No. of Pages : 200 Pages | Category : Healthcare

According to Vision Research Reports, the global continuous renal replacement therapy market size was valued at US$ 878 Mn in 2020, and to surpass around US$ 2 billion by 2028 with a CAGR of 7.2% during the forecast period 2021 to 2028.

Continuous renal replacement therapy (CRRT) is a preferred modality for managing hemodynamically patients suffering from acute kidney injury. CRRT is advised to be performed continuously for 24 hours per day on the patient for venovenous vascular access. Rise in the rate of acute kidney injuries across the globe is likely to boost the need for continuous renal replacement in critically-ill patients.

The expansion of the global continuous renal replacement therapy market can be attributed to technological advancements in CRRT systems and investments toward the research & development of CRRT systems. Moreover, increase in the geriatric population is another factor fueling the need for continuous renal replacement therapy, as comorbidities can be found in the elderly population. Moreover, surge in the number of dialysis centers across the world is expected to propel the global continuous renal replacement therapy market.

Europe dominated the global continuous renal replacement therapy market in 2018, and the trend is anticipated to continue during the forecast period. This can be ascribed to the presence of key players, growing patient pool, favorable reimbursement policies, and technological advancements in continuous renal replacement therapy systems in the region. However, shortage of trained staff and high cost of CRRT systems are likely to hamper the continuous renal replacement therapy market in the region during the forecast period.

Asia Pacific is expected to be a highly lucrative continuous renal replacement therapy market during the forecast period, owing to increasing healthcare infrastructure, along with rise in the incidence of acute kidney injury in the region.

Rise in Incidence of Diabetes and Hypertension to Drive Market

Increasing incidence of chronic diseases, such as diabetes and hypertension, fuels the risk of developing acute kidney injury. According to the National Diabetes Statistics report by CDC (Centers for Disease Control and Prevention), in 2017, 30.3 million people in the U.S. were suffering from diabetes, which accounted for around 9.4% of the total population. Approximately 23.1 million people were diagnosed with diabetes in the U.S. Lack of awareness about diabetes could lead to serious renal issues in the future. According to data published by WHO in May 2019, 1.13 billion people are estimated to be suffering from hypertension, globally. Rise in elevated blood pressure rates is likely to affect the patient population in low- and middle-income countries. Hypertension causes around 9.4 million deaths globally every year. It can affect AKI patients and may result in acute renal failure. This factor is propelling the demand for CRRT systems.

Benefits of Continuous Renal Replacement Therapy Systems in Pediatric Patients

Technological advancements of continuous renal replacement therapy in critically-ill AKI pediatric patients have resulted in a decline in mortality rates from 4.6% to 2.4% in 2020. PrismaFlex HF20 and Aquadex are a few approved CRRT systems for pediatric patients. According to a study published by NCBI (National Center for Biotechnology Information) in October 2020, continuous renal replacement therapy is most effective in critically ill pediatric patients with acute kidney injury. The study also mentions recent updates in standard CRRT systems for pediatric patient care, which includes the adoption of new generation machines and improvement in the condition of children, such as sepsis care, lung protective ventilation, etc.

Increase in Geriatric Population to Fuel Demand for CRRT Systems

The geriatric population is likely to suffer more from chronic diseases, such as acute kidney injury and other kidney diseases as compared to the younger population. Moreover, the geriatric population is increasing at a rapid pace as compared to the younger population. Increase in the geriatric population is projected to drive the incidence of chronic diseases such as kidney failure, end stage renal diseases, Alzheimer’s, dementia, cancer, immune diseases, etc., which, in turn, is anticipated to boost the need for the corrective treatment of these conditions. This is estimated to further drive the demand for clinical trials and research, which will require the development of continuous renal replacement therapy systems. These factors are expected to drive the global continuous renal replacement therapy market. According to the United Nations, the geriatric population aged above 60 is expected to grow two-fold by 2050 and three-fold by 2100, an increase from 962 million in 2017 to 2.1 billion by 2050 and 3.1 billion by 2100.

Technological Developments to Drive CRRT Market

Technological advancements are driving innovations in continuous renal replacement therapy. Continuous renal replacement therapy devices have enabled the support of multiple organ therapy using different continuous renal replacement therapy modalities in the past few years. Technological advancements have also enabled the usage of the precision continuous renal replacement therapy principle to develop devices with upgraded circuits to extend support to other organs, apart from the kidneys. Another development is obtaining information about the patient’s health through technology-assisted devices to study and analyze multiple treatments. The development of fourth-generation continuous renal replacement therapy devices, such as ACUsmart, offers a smart and optimal device for critically-ill patients.

Continuous Venovenous Haemofiltration (CVVH) Mode to Lead CRRT Market

Continuous venovenous hemofiltration (CVVHF) is the most preferred technique. In terms of mode, the continuous veno venous haemofiltration (CVVHF) segment is likely to account for a major share of the continuous renal replacement therapy market. CVVH is more effective than continuous venovenous haemodiafiltration (CVVHDF), and may be associated with fewer complications. This mode offers a higher ultrafiltration rate as compared to other modes. Based on product, the disposables segment accounted for the largest share of the global CRRT market in 2020, owing to a rise in the usage of bloodline sets in more than one type of CRRT modes, and benefits of hemofilters in continuous dialysis. Disposables are specific to every machine, and are usually designed for a specific treatment modality. The disposables product segment is further divided into bloodline sets, hemofilters, and other disposables. Moreover, the low cost of disposables and rise in dependency of physicians on disposables are propelling the segment.

Hospitals to Dominate Global CRRT Market

In terms of end user, the continuous renal replacement therapy market has been segmented into hospitals, clinics, and others. The hospitals segment held the largest market share in 2020, and will continue its dominance during the forecast period. Rise in the number of critically-ill patients across the globe is resulting in increase in patient admissions in ICUs in hospitals. Moreover, surge in the number of hospitals, globally, is also expected to boost the segment’s growth. The hospitals segment is driven by top-class facilities with continuous renal replacement therapy systems in ICUs across the world. Furthermore, patient preference for hospitals is also driving the segment. The presence of a large number of hospitals, highly-equipped infrastructure, use of technologically-equipped products, and favorable healthcare insurance policies in emerging economies are anticipated to drive the segment during forecast period.

Prominent Regions

In terms of region, the global continuous renal replacement therapy market has been segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Europe dominated the global continuous renal replacement therapy market in 2020, followed by North America. Europe accounted for a major share of the global continuous renal replacement therapy market in 2020. This can be attributed to the large patient pool suffering from acute kidney injury, technological advancements, favorable reimbursement policies, and well-defined regulatory framework in the region. Several key players of continuous renal replacement therapy systems are based in Europe. The continuous renal replacement therapy market in Asia Pacific is projected to expand at a high CAGR from 2019 to 2028. This can be attributed to increase in healthcare expenditure and a large patient population in countries such as India and China. For instance, Fresenius Medical Care plans to expand in China, aiming to open around 100 dialysis centers in the next five years. Moreover, leading players in the global continuous renal replacement therapy market are undertaking initiatives to reach maximum ESRD patients across all regions by setting up more dialysis centers. For instance, B. Braun Melsungen AG alone has more than 300 centers across Europe, Africa, and Asia Pacific.

Product Launch and Merger & Acquisition Strategies to Drive Global CRRT Market

The global continuous renal replacement therapy market is highly competitive in terms of number of players. Key players operating in the global continuous renal replacement therapy market include Baxter International, Inc, Nipro Corporation , Fresenius Medical Care AG & Co. KGaA, Asahi Kasei Corporation, B. Braun Melsungen AG, Medica SPA,  INFOMED SA, Medtronic (Bellco Società unipersonale a r.l.), and Toray Medical Company Limited (Toray Industries, Inc.). These players have adopted various strategies, such as product portfolio expansion, innovative products development, and investments in mergers & acquisitions to establish a strong distribution network. For instance, in February 2019, Fresenius Medical Care acquired NXStage Medical, Inc., a home dialysis product manufacturer, aiming to boost the trend of using continuous renal replacement therapy systems at home. Prominent market player Baxter International launched PrisMax in the U.S., in July 2019, to offer its product to enhance the health condition of critically-ill patients.

Market Segmentation

By Mode

  • Slow Continuous Ultrafiltration (SCUF)
  • Continuous Venovenous Haemofiltration (CVVHF)
  • Continuous Venovenous Haemodialysis (CVVHD)
  • Continuous Venovenous Haemodiafiltration (CVVHDF)

By Product

  • Dialysate & Replacement Fluids
  • Disposables
    • Bloodline Sets
    • Hemofilters
    • Other Disposables
  • Systems

By Therapy

  • Renal
  • Non-renal
  • Combination

By End User

  • Hospitals
  • Clinics
  • Others

By Region

  • North America
    • U.S.
    • Canada
    • Rest of North America
  • Europe
    • Germany
    • France
    • U.K.
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Rest of Asia Pacific
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa
  • South America
    • Brazil
    • Rest of South America

Report Scope

The Continuous renal replacement therapy market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Continuous renal replacement therapy market for the base year 2020 and the forecast between 2021 and 2028. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Continuous renal replacement therapy market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Continuous renal replacement therapy market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Continuous renal replacement therapy market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Continuous renal replacement therapy capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Continuous renal replacement therapy by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Continuous renal replacement therapy market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2028. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Continuous renal replacement therapy market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Continuous renal replacement therapy market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Continuous renal replacement therapy industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

Continuous renal replacement therapy market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Continuous renal replacement therapy market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Continuous renal replacement therapy market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Continuous renal replacement therapy market. These factors have benefited the growth of the global market for Continuous renal replacement therapy. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Continuous renal replacement therapy. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Continuous renal replacement therapy are as follows:

  • History Year: 2017-2020
  • Base Year: 2020
  • Forecast Year 2021 to 2028

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2028);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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