The global electroporation instruments market size is projected to reach US$ 241 million by 2027, expanding at a CAGR of 6% from 2020 to 2027.
The electroporation technique involves exposure of cell membranes to high-intensity electric pulses that cause a temporary destabilization in certain areas of the cell. During this transient destabilization event, the cell membrane becomes highly permeable and allows the entry of various exogenous molecules, including the DNA. Electroporation is an easy, non-chemical technique that yields high transformation efficiencies in various cell types. This technique does not alter target cell morphology and functions; however, the technique can cause cell death if transfection is not carried out under optimum conditions.
Technological Advancements to Boost Adoption of Electroporation for Treatment of Internal Tumor
Technological advancements have led to the efficient use of electroporation in the treatment of internal tumor. Electrochemotherapy is considered highly effective in the treatment of cutaneous and subcutaneous tumor. Features of the electroporation technique, such as high specificity for targeting cancer cells and high degree for localization of treatment result in better treatment of internal tumors. Advancements in the electroporation technology present better treatment option of liver and bone metastases, brain tumors, soft tissue sarcomas, and colorectal and esophageal tumors. Safe performance of electrochemotherpay in the treatment of internal tumors would be defined by non-interference with the heart’s electrical activity. The complete removal internal tumors includes positioning the electrode accurately to extend the electroporation in all tumor cells and to avoid damaging the healthy tissue or organs in the vicinity.
Total Electroporation System to Gain Significant Market Share
In terms of product, the global electroporation instruments market has been segmented into total electroporation system, eukaryotic electroporation system, and microbial electroporation system. Increase in the burden of diseases across the globe has prompted various healthcare organizations to focus on drug discovery and drug development. These studies require application of experimental drugs on human and other eukaryotic cells to study their mechanism of action and their safety profile. Rise in demand for multifaceted devices that can be used for all types of cell studies leading to overall cost-effectiveness is anticipated to drive the total electroporation system during the forecast period.
Bio-Medical Research to be Highly Lucrative
Based on application, the global electroporation instruments market has been classified into bio-medical research, therapeutic delivery, and protein production. The bio-medical research segment has been further sub-segmented into transgenic models, cancer research, gene and protein expression studies, and cell based microarrays for drug discovery and development. The therapeutic delivery segment has been further split into biotherapeutics, and electro-chemotherapy and electro-immunotherapy. The bio-medical research segment is likely to maintain its dominance during the forecast period. The segment is expected to expand significantly over the next few years due to increase in applications of electroporation in microbiology, oncology, surgery, biochemistry, public health, and other non-communicable diseases.
Market Growth Likely to Remain Steady amid COVID-19 Pandemic
The impact of the COVID-19 pandemic on the global electroporation instruments market is expected to remain moderate in 2020, as research and development activities are likely to remain unaffected. Furthermore, increasing adoption of the gene editing technology across the healthcare sector worldwide is likely to continue in 2020 due to which, the electroporation instruments market is projected to witness steady growth. As precision medicines are playing an imperative role in assisting researchers and scientists to evaluate the novel coronavirus, the demand for electroporation instruments is likely to grow. In addition, CRISPR-based diagnostics are increasingly being used to accurately diagnose a range of medical diseases, including the novel COVID-19 infection– another factor that is expected to propel the growth of the market for electroporation instruments during the COVID-19 era.
Impressive Approval Rate and Growing Adoption in Developed Regions to Bolster Market Growth
Developed regions, including North America and Europe are expected to provide lucrative growth opportunities to the players involved in the current electroporation instruments market landscape. The advanced healthcare infrastructure coupled with rapid advancements in technology is expected to play an imperative role in boosting the growth of the electroporation instruments market in these regions. Furthermore, the approval rate of electroporation instruments across Europe and North America is comparatively higher than that across the Asia Pacific region. In addition, as electroporation continues to gain considerable adoption across Europe due to the increasing approval for the clinical use of electro chemotherapy, market players are likely to focus on tapping into the opportunities across the European Union. Furthermore, as regulations and guidelines pertaining to the adequate usage of electroporation instruments continue to being published, the demand for electroporation instruments continues to grow.
Progress in Gene Editing Techniques to Propel Market Growth
Advancements in gene editing technologies, including regularly-interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins or transcription activator-like effector nucleases (TALENs) have enabled researchers to curate targeted sequence-specific changes across the DNA– a factor that is expected to increase the adoption of electroporation instruments in the upcoming years. As advancements in gene-editing techniques occur at a consistent pace, the prospects of the electroporation instruments market continue to stare at a bright future. Furthermore, as applications of gene editing techniques continue to expand owing to research and development, the adoption of electroporation instruments is likely to witness a considerable growth. In addition, major advancements in the electroporation instruments and electrodes coupled with the increasing compatibility with cutting-edge gene editing technology are likely to play a key role in the overall development of the global electroporation instruments market.
Furthermore, as electroporation penetrates 3D structures with high levels of efficiency, advanced gene editing techniques are likely to gain further traction in the upcoming decade. Moreover, in the current scenario, players operating in the current electroporation instruments market are increasingly focusing on launching preset starting electroporation parameters for highly common samples, which, in turn, is likely to minimize the degree of optimization for researchers.
North America to Dominate Global Market
In terms of region, the global electroporation instruments market has been divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global electroporation instruments market in 2019, followed by Europe. Rise in prevalence of cancer and autoimmune diseases in North America boosted the transfection technology market. Biotherapeutic drugs are highly preferred for the treatment of cancer and autoimmune diseases. Increase in usage of these drugs is estimated to fuel the demand for transfection, as transfection is extensively employed for the production of biotherapeutic drugs.
Major players operating in the global electroporation instruments market are BEX Co. Ltd., Celetrix LLC, Merck KGaA, Eppendorf AG, Harvard Bioscience Inc. (BTX), Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, MaxCyte Inc., Lonza Group, and Mirus Bio LLC.
Scope of the Report
VRR’s report on the global electroporation instruments market studies past as well as current growth trends and opportunities to gain valuable insights of these indicators for the market during the forecast period from 2020 to 2030. The report provides the revenue of the global electroporation instruments market for the period 2018–2030, considering 2020 as the base year and 2030 as the forecast year. The report also provides the compound annual growth rate (CAGR) of the global electroporation instruments market during the forecast period.
The report has been prepared after extensive primary and secondary researches. Primary research involved bulk of research efforts, wherein analysts carried out interviews with industry leaders and opinion makers. Secondary research involved referring to key players’ product literature, annual reports, press releases, and relevant documents to understand the global electroporation instruments market.
Secondary research also included Internet sources, statistical data from government agencies, websites, and trade associations. Analysts employed a combination of top-down and bottom-up approaches to study various phenomenon in the global electroporation instruments market.
The report includes an elaborate executive summary, along with a snapshot of the growth behavior of various segments included in the scope of the study. Furthermore, the report sheds light on changing competitive dynamics in the global electroporation instruments market. These indices serve as valuable tools for existing market players as well as for entities interested in entering the global electroporation instruments market.
The report delves into the competition landscape of the global electroporation instruments market. Key players operating in the global electroporation instruments market have been identified, and each one of these has been profiled for distinguishing business attributes. Company overview, financial standings, recent developments, and SWOT are some of the attributes of players in the global electroporation instruments market that have been profiled in this report.
Key Questions Answered in Electroporation Instruments Market Report
A unique research methodology has been utilized by VRR to conduct a comprehensive research on the growth of the global electroporation instruments market and arrive at conclusions on the growth prospects of the market. This research methodology is a combination of primary and secondary research, which helps analysts warrant the accuracy and reliability of the drawn conclusions.
Secondary sources referred to by analysts during the production of the global electroporation instruments market report include statistics from company annual reports, SEC filings, company websites, World Bank database, investor presentations, regulatory databases, government publications, and industry white papers. Analysts have also interviewed senior managers, product portfolio managers, CEOs, VPs, and market intelligence managers, who have contributed to the production of VRR’s study on the electroporation instruments market as primary sources.
These primary and secondary sources have provided exclusive information during interviews, which serves as a validation from electroporation instruments market leaders. Access to extensive internal repository and external proprietary databases allows this report to address specific details and questions about the global electroporation instruments market with accuracy. The study also uses the top-down approach to assess the revenue numbers for each segment and the bottom-up approach to counter-validate them. This has helped in reaching VRR’s estimates on future prospects of the global electroporation instruments market more reliably and accurately.
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