According to market report, the global exosome technologies market reached value at US$ 31 Mn in 2020 and projected to hit US$ 300 million by 2030, expanding growth at a CAGR of 23.5% from 2021 to 2030.
Exosomes are extracellular vehicles secreted from human body cells. Exosomes play a crucial role in the intercellular transportation of protein and RNA. Recently, exosomes have been tested for numerous therapeutic applications, including biomarkers, drug delivery systems, and therapies for diseases such as cancer, renal neurological, and cardiovascular diseases. Increase in awareness about exosome technologies & government initiatives are the key factors projected to drive the global exosome technologies market during the forecast period.
Rise in Prevalence of Chronic Diseases to Drive Global Market
The prevalence of cardiovascular diseases has increased across the globe due to change in dietary habits. According to Centers for Disease Control and Prevention statistics, heart diseases account for nearly 655,000 deaths in the U.S. each year. Cancer is also a leading cause of death globally, caused due to lifestyle-related factors such as alcohol consumption, tobacco consumption, and some food-related factors. According to the World Health Organization statistics, in 2018, an estimated 18.1 million new cases of cancer and 9.6 million deaths were reported across the globe. Aging is considered a major risk factor for neurodegenerative diseases. Therefore, a surge in the geriatric population contributes to the increase in the number of patients with various brain diseases. Moreover, changing environmental conditions and human behavior affect the spread and impact of infectious diseases. Therefore, rise in prevalence of various chronic diseases is likely to boost the global exosomes technologies market during the forecast period.
Exosomes Possess Huge Potential in Field of Cancer Immunotherapy
Cell-derived nanovesicles also known as exosomes have the potential to increase clinical outcomes in cancer immunotherapy, owing to their advantageous immunogenicity and molecular transfer function. Companies in the exosome technologies market are adopting proprietary manufacturing platforms to develop EVs that help to regulate immune responses. They are boosting their production capabilities to develop exosomes that are derived from tumor cells and immune cells, which exhibit unique composition profiles that are directly linked with anti-cancer immunotherapy.
Exosomes hold promising potentials to deliver their cargoes to targeted cells and influence the phenotype and immune-regulation functions of targeted cells. Thus, companies in the exosome technologies market are gaining awareness that exosomes have huge potential in the field of cancer immunotherapy.
Exosomes Regulate CVD Progression via Exchange of Signal Molecules
Exosomes, also known as extracellular vesicles with a lipid bilayer membrane of endosomal origin have become the focus of a large body of research in cardiovascular diseases (CVD) for companies in the exosome technologies market. These EVs serve as carriers for signal molecules responsible for intracellular and inter-organ communication underlying CVD pathophysiology. Moreover, they help to overcome limitations of the stem cell therapy, since exosomes released by progenitor cells are bioactive and act as key mediators for the stem cell therapy of CVD.
Exosomes play a critical role in cardiovascular pathophysiology, as they help to regulate CVD progression via transport and exchange of signal molecules. For instance, exosomes released by cardiac fibroblasts rescue cardiomyocytes from ischemia-reperfusion injury.
In terms of exosome type, the global exosome technologies market has been bifurcated into loaded cargo and non-cargo. The loaded cargo segment dominated the market in 2020. Exosomes carry various types of proteins, lipids, and nucleic acids (mRNA and non-coding RNA). Exosomes with therapeutic cargo help to cross the natural membranous barriers, such as the blood-brain barrier (BBB), to achieve better therapeutic efficiency of brain diseases. This, in turn, is projected to drive the segment.
Based on cell source, the global exosome technologies market has been classified into HEK293, MSCs, platelets, erythrocytes, natural killer cells (NKs), and others. The MSCs segment dominated the global exosome technologies market in 2020, and the trend is anticipated to continue during the forecast period. MSCs have immunomodulatory properties to regulate various cells involved in immune responses and exhibit potent cell therapeutics for various diseases for the last few decades. This factor is expected to propel the segment.
In terms of indication, the global exosome technologies market has been categorized into therapeutics and diagnostics. The diagnostics segment held major share of the global exosome technologies market in 2020. The segment’s dominance can be attributed to reimbursement, availability, and approval of new exosome diagnostics products.
Based on end user, the global exosome technologies market has been divided into healthcare providers, pharmaceutical & biotechnology companies, and others. The healthcare providers segment held a major share of the global exosome technologies market in 2020. The segment’s dominance can be attributed to the increase in the geriatric population suffering from various diseases.
North America is projected to account for prominent share of the global exosome technologies market during the forecast period. Extensive in-house manufacturing & research capacity, large customer base, and a well-established healthcare infrastructure are the major factors driving the market in North America.
The market in Europe is anticipated to expand at a high CAGR in the near future, owing to strategies adopted by key players and grants of patent for exosomes in the region.
The exosome technologies market in Asia Pacific is projected to grow at a rapid pace in the near future. This can be attributed to government initiatives to improve healthcare infrastructure. For instance, the Government of Japan and a team of industry players announced a collaboration leveraging exosomes to improve cancer diagnosis and its treatment.
Key players operating in the global exosome technologies market are Aegle Therapeutics, Anjarium Biosciences, Aruna Biomedical, Carmine Therapeutics, Ciloa SAS, Codiak BioSciences, Creative Biolabs, Danaher Corporation (Beckman Coulter), Direct Biologics, ExoCan Healthcare Technologies Pvt. Ltd., ExoCoBio, ExonanoRNA LLC, Exopharm, Exosome Diagnostics, Inc. (BIO-TECHNE CORPORATION), Fujifilm, ILIAS Biologics, Inc., Illumina, Inc., Invitrix Therapeutics, XOStem, Inc., VivaZome Therapeutics Pty Ltd., Thermo Fisher Scientific, Inc., Organicell, OmniSpirant Ltd., and Novadip Biosciences.
By Exosome Type
By Cell Source
By End User
This report focuses on exosome technologies market includes crucial information on market share, market size, and growth rate for the forecast period 2021 to 2030 at the global level, regional level and company level. From a global perspective, this report represents overall exosome technologies market size by analyzing historical data and future prospect. The study highlights deep analysis on the major drivers of the market, restraints, and challenges to help the business owners, suppliers, and marketing personnel in planning effective strategies for the forecast period. This will help the business and manufacturers to lead the market and gain prominent position in future. The report also presents vital information through graphical representation on factors like table, charts, and statistics. The study includes drivers and restraints of the global exosome technologies market.
The research not only conducts forecasts in terms of value, but also evaluates the market on the basis of essential parameters, such as Year-on-Year (Y-o-Y) growth. This helps providers to recognize the future opportunities as well predictability of the market.
In order to understand and assess opportunities in this market, the report is categorically divided into five key sections on the basis of segments. The report analyzes the global market in terms of value (US$ dollers) and volume (Million Units).
The research report includes specific segments by region (country), by company, by all segments. This study provides information about the growth and revenue during the historic and forecasted period of 2017 to 2030. Every segment is further sub-segmented into several sub-segmented that are deeply analyzed by experts to offer valuable information to the buyers and market players. Understanding the segments helps in identifying the importance of different factors that aid the market growth.
The research report includes a detailed study of regions of North America, Europe, China, Japan and Rest of the World. The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2017 to 2030. These analyses will help the reader to understand the potential worth of investment in a particular region.
The report provides in-depth segment analysis of the global exosome technologies market, thereby providing valuable insights at macro as well as micro levels. Analysis of major countries, which hold growth opportunities or account for significant share has also been included as part of geographic analysis of the exosome technologies market.
The report includes country-wise and region-wise market size for the period 2017-2030. It also includes market size and forecast by segments in terms of production capacity, price and revenue for the period 2017-2030.
In this study, the years considered to estimate the market size of exosome technologies are as follows:
This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2017 to 2019.
The analysts have provided a comprehensive analysis of the competitive landscape of the global exosome technologies market with the company market structure and market share analysis of the top players. The innovative trends and developments, mergers and acquisitions, product portfolio, and new product innovation expected to provide a dashboard view of the market, ultimately providing the readers accurate measure of the current market developments, business strategies, and key financials.
Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.
Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users) and other segments.
The research methodology adopted by analysts for compiling the global exosome technologies market report is based on detailed primary as well as secondary research. With the help of in-depth insights of the market-affiliated information that is obtained and legitimated by market-admissible resources, analysts have offered riveting observations and authentic forecasts for the global market.
During the primary research phase, analysts interviewed market stakeholders, investors, brand managers, vice presidents, and sales and marketing managers. Based on data obtained through interviews of genuine resources, analysts have emphasized the changing scenario of the global market.
For secondary research, analysts scrutinized numerous annual report publications, white papers, market association publications, and company websites to obtain the necessary understanding of the global exosome technologies market.
The study objectives of this report are:
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