The global Exosomes market size is expected to be worth around US$ 5.28 billion by 2030, according to a new report by Vision Research Reports.
The global Exosomes market size was valued at US$ 4.00 billion in 2020 and is anticipated to grow at a CAGR of 20.8% during forecast period 2021 to 2030.
Nanovesicles, which play a major role in intercellular communication, are anticipated to witness a significant rise in R&D, thus leading to revenue growth in the coming years.
Application of these vesicles as carriers of functional content such as circulating nucleic acids, lipids, and proteins can be attributed to market growth. In addition, exosomes play an important role in immunosurveillance and tumor pathogenesis. Increasing research programs focusing on determining the role of exosomes in hepatocellular carcinoma (HCC) is estimated to drive the market.
The rising number of articles pertaining to exosomal research is encouraging R&D activities in the field. Currently, there are more than 4400 articles published about exosomes, with approximately 25% of these published in 2016 alone. In addition to the exponential rise in article publication, the number of companies engaged in the research is also increasing.
These companies are taking advantage of the natural propensity of exosomes for the transmission of macromolecule payloads between cells. The application of these molecules in research activities related to therapeutics and diagnostics is projected to result in exponential growth in the coming years.
Moreover, an increase in funding for R&D in this field is poised to positively influence industrial growth. Rise in funding capacity by public and private institutions is indicative of the importance of exRNA molecules across the community engaged in translational research pertaining to diagnostics and therapeutic product development.
On the basis of workflow, isolation methods and downstream analysis are two major segments. The downstream analysis accounted for the larger share owing to the growing need for advanced technologies and instrumentation for downstream processing.
Isolation methods comprise ultracentrifugation, immunocapture, precipitation, and filtration. While ultracentrifugation dominated the segment with respect to revenue, other methods are anticipated to witness a similar growth pattern due to fragmented research being carried out in isolation protocols. Ultracentrifugation is considered to be the gold standard of purification. Easy availability of instruments and reagents for this method is attributive to its large market share.
Within the downstream analysis segment, flow cytometry dominated the market with respect to revenue owing to higher usage in the process. Availability of clever solutions and straightforward protocols for the cytometric method has supported the growth of this sub-segment. RNA analysis using NGS and PCR is expected to witness lucrative growth in the coming years due to a rise in the number of platforms installed for NGS analysis.
Different types of biomolecules are used for exosomal analysis; these include non-coding RNAs, mRNA (exoRNA), peptides or proteins, DNA fragments, and lipids. Non-coding RNAs constitute miRNAs and long non-coding RNAs (lncRNAs).
Non-coding RNAs are being increasingly used for research purposes and this has enabled them to emerge as the dominant segment. Functions of lncRNA are believed to be associated with mental and psychiatric disorders, tumor growth, and imprinting. Development of specific protocols for research in non-coding RNA and the prediction of its secondary structure is anticipated to drive the growth of this segment.
Application of pre-clinical animal models in research to assess the feasibility of detecting tumor-associated genetic mutations in circulating exoDNA is expected to boost the DNA fragments segment in the coming years. Exosomal DNA possesses translational potential as a circulating biomarker for cancer, a factor that also supports the growth of this segment.
By way of application, cancer dominates the overall exosomes market due to the growing role of exosomes in cancer research. Contribution of exosomes for tumorigenesis, chemotherapeutic resistance, and development of novel cancer treatments through the identification of cancer biomarkers is also responsible for the growth of this segment. Exosomes are used not only as a drug delivery method and for chemotherapeutic sensitization but also as a non-invasive biomarker. This has led to increased R&D on these messengers.
The neurodegenerative disorders segment offers significant scope for expansion, owing to the study of exosomes and related extracellular vesicles being carried out in the field. Research in this segment is vital in unveiling the use of exosomes as therapeutic tools for brain disorders as well as biomarkers of the disease state.
North America accounted for the largest revenue share with respect in 2016 and this can be attributed to extensive funding in the U.S. For instance, in March 2017, researchers at the Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine received two grants from the Sohn Conference Foundation for R&D in isolation and characterization of tumor-derived exosomes to study cancer occurrence in children.
Asia Pacific is expected to emerge as the fastest-growing region due to immense potential identified in emerging economies such as China and India. Competitive strategies adopted by players to carry out R&D activities in this sector are thanks to constant government support and this is likely to support the growth of the Asia Pacific market.
Fujifilm; Thermo Fisher Scientific, Inc.; Danaher; Lonza; Illumina, Inc.; Qiagen; Takara Bio Company; Malvern Instruments Ltd.; Miltenyi Biotec; and MBL International Corporation.
Immunocapture on beads
Cell Surface Marker Analysis using Flow Cytometry
Protein analysis using Blotting & ELISA
RNA analysis with NGS & PCR
Proteomic analysis using Mass Spectrometry
Biomolecule Type Outlook (Revenue, USD Million, 2014 - 2030)
The Middle East and Africa (MEA)
The Exosomes market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.
The report provides size (in terms of volume and value) of Exosomes market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.
This report focuses on the global Exosomes market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Exosomes market development in United States, Europe and China.
It is pertinent to consider that in a volatile global economy, we haven’t just conducted Exosomes market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.
In terms of production side, this report researches the Exosomes capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.
In terms of consumption side, this report focuses on the consumption of Exosomes by regions (countries) and application.
Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Exosomes market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.
With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Exosomes market companies.
Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Exosomes market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.
The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.
Overall, this is an in-depth research report specifically for the Exosomes industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.
The Exosomes market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Exosomes market.
Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Exosomes market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.
Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Exosomes market. These factors have benefited the growth of the global market for Exosomes. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.
New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Exosomes. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).
In this study, the years considered to estimate the market size of Exosomes are as follows:
Reasons to Purchase this Report:
- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.
This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.
Market Size Estimation
Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).
The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.
Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.
All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.
Market Breakdown and Data Triangulation
After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.
Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.
In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.
The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.
The study objectives of this report are:
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