In Situ Hybridization Market (By Technology: Fluorescent In Situ Hybridization (FISH), Chromogenic In Situ Hybridization (CISH); By Probe Type: DNA, RNA; By Product: Instruments, Kits & Probes, Software, Services; By Application: Cancer, Cytogenetics, Developmental Biology, Infectious Diseases; By End-use: Hospitals & Diagnostic Laboratories, CROs, Academic& Research Institutes) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

Published Date : Dec 2021 | No. of Pages : 150+ Pages | Category : Healthcare

The global In Situ Hybridization market size is expected to be worth around US$ 3.6 billion by 2030, according to a new report by Vision Research Reports.

The global In Situ Hybridization market size was valued at US$ 2,333.5 million in 2020 and is anticipated to grow at a CAGR of 9.9% during forecast period 2021 to 2030.

In Situ Hybridization Market Size 2021 to 2030

Report Coverage

Report Scope Details
Market Size US$ 3.6 billion by 2030
Growth Rate CAGR of 9.9% From 2021 to 2030
Base Year 2021
Forecast Period 2021 to 2030
Segments Covered Technology, Probe type, Application, Product, End-use
Regional Scope North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Companies Mentioned PerkinElmer, Inc.; Thermo Fisher Scientific Inc.; BioView; Agilent Technologies; Merck KGaA; Bio-Rad Laboratories, Inc.; Oxford Gene Technology; Leica BiosystemsNussloch GmbH; NeoGenomics Laboratories; Advanced Cell Diagnostics, Inc.

Growth Factors

The market is gaining momentum in breast cancer with the FISH test. For instance, Roche offers a comprehensive ISH workflow solution with automated assay and digital pathology for breast cancer. Thus, increasing the scope of application is expected to drive the market to a major extend. In addition, technological advancements in instruments have fueled the market growth.

The COVID-19 is found to have a mixed impact on the market space. Social distancing mandates and lockdown policies have negatively affected the market to a considerable extent. However, the pandemic has opened new opportunities for operating entities by allowing them to deploy ISH methods in the R&D of COVID-19 related programs.

By Technology Analysis

Based on technology, the FISH segment dominated the market for in situ hybridization and accounted for the largest revenue share of 53.9% in 2020. This can be attributed to the wide range of applications such as diagnosing congenital diseases including Edward's Syndrome and Down's Syndrome.

The CISH segment also captured a significant share of in situ hybridization over time as it is a cost-effective, reliable, and practical alternative for FISH. The technology aids in detecting HER-2/neu oncogene copies with conventional peroxidase reaction. 

The affordable technological advancements in the ISH market are driving the segment growth. For instance, a group of researchers published their study in May 2021, suggesting that the chromogen-based RNA in situ hybridization approach is an effective method to detect druggable cytokines in atopic dermatitis and psoriasis.

By Probe Analysis

The DNA probe segment dominated the market for in situ hybridization and accounted for the largest revenue share of 51.1% in 2020. However, the RNA probe showcased a better growth rate in the forecasted period, owing to the development of new nucleic acid-based diagnostic assays and tools for analyzing DNA and RNA molecules.

RNA probe is used to detect the presence of complementary nucleic acid sequences by hybridization. The popularity of RNA as a hybridization tool is increasing owing to several advantages, such as the probes are synthesized by in vitro transcription and can be a replacement for DNA probes in almost all applications.  The acceleration in the development of probe-based technology and products is anticipated to boost the growth of the ISH market.

By Product Analysis

The instruments segment dominated the market for in situ hybridization and accounted for the largest revenue share of 36.3% in 2020. The increasing demand for instruments is owing to the raising chains of diagnostic and research laboratories. Bio-Techne Corporation announced to introduce RNAscope technology along with new DNA scope assays in the commercial market.

On the other hand, the services segment is anticipated to witness significant growth in the market for in situ hybridization. Increasing outsourcing to improve operational functionalities and ensure high adherence to quality standards and is contributing toward the lucrative CAGR of this segment.

By Application Analysis

The cancer segment dominated the market for in situ hybridization and accounted for the largest revenue share of 36.4% in 2020. The increase in the incidence rate of cancer cases is anticipated to drive the growth.

Rising unhealthy lifestyle, aging population, health conditions, and environment are leading factors for causing cancers. Various organizations initiate research and promote further development in the treatment of cancers. 

By End-use Analysis

The hospitals and diagnostic laboratories segment dominated the market for in situ hybridization and accounted for the largest revenue share of 48.8% in 2020. There are three major end-users in the market, hospitals and diagnostic laboratories, Contract Research Organizations (CROs), and academic and research institutions.

The ongoing pandemic can be the key driver for the laboratories as understanding the pathogen can offer a competitive advantage to the laboratories and assist to lead the industry. 

Many organizations outsource their research and clinical trials to research laboratories and factors such as specialized workforce, deduces the cost for companies, and improving the efficiency can motivate companies and other organizations to outsource their research to the laboratories.

By Regional Analysis

North America dominated the In Situ Hybridization (ISH) market and accounted for the largest revenue share of 44.9% in 2020. This growth in the region can be attributed to the presence of a considerable number of market players and incentivized research projects by the regional government.

Asia Pacific, the market is likely to witness the fastest growth over the forecast period. Raising the attention of regional authorities in R&D is expected to be the key market driver over the forecast period. China and India are the fastest-growing markets in the Asia Pacific region.

Key Players

  • Leica Biosystems Nussloch GmbH

  • Merck KGaA

  • Thermo Fisher Scientific

  • Agilent Technologies

  • BIO VIEW

  • PerkinElmer, Inc.

  • NeoGenomics Laboratories, Inc.

  • Bio-Rad Laboratories, Inc.

  • Oxford Gene Technology

  • Advanced Cell Diagnostics, Inc. 

Market Segmentation

  • By Technology

    • Fluorescent In Situ Hybridization (FISH)

    • Chromogenic In Situ Hybridization (CISH)

  • By Probe Type 

    • DNA

    • RNA

  • By Product

    • Instruments

    • Kits & Probes

    • Software

    • Services

  • By Application 

    • Cancer

    • Cytogenetics

    • Developmental Biology

    • Infectious Diseases

    • Others

  • By End-use 

    • Hospitals & Diagnostic Laboratories

    • CROs

    • Academic& Research Institutes

    • Others

  • Regional

    • North America

      • U.S.

      • Canada

    • Europe

      • U.K.

      • Germany

      • France

      • Italy

      • Spain

    • Asia Pacific

      • Japan

      • China

      • India

      • South Korea

      • Australia

    • Latin America

      • Brazil

      • Mexico

    • Middle East & Africa

      • South Africa

      • Saudi Arabia

The In Situ Hybridization market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of In Situ Hybridization market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global In Situ Hybridization market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the In Situ Hybridization market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted In Situ Hybridization market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the In Situ Hybridization capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of In Situ Hybridization by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global In Situ Hybridization market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major In Situ Hybridization market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of In Situ Hybridization market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the In Situ Hybridization industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

In Situ Hybridization market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to In Situ Hybridization market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of In Situ Hybridization market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new In Situ Hybridization market. These factors have benefited the growth of the global market for In Situ Hybridization. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for In Situ Hybridization. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of In Situ Hybridization are as follows:

  • History Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:


- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

To strategically profile the key players and comprehensively analyze their growth strategies.


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