The in vitro toxicology testing market size is projected to surpass USD 15.4 billion by 2027 growing at a CAGR of 10.3%.
The key factors driving the growth of this market include opposition to animal testing, growing demand for in vitro technology in the European market, new and promising technologies, and increasing R&D expenditure to detect toxicity at an early stage.
The consumables segment is expected to account for the largest share of the in vitro toxicology testing market in 2019
Consumables are expected to be the largest revenue contributor to the in vitro toxicology testing market in 2019. The large share of this segment can be attributed to the increasing demand for high-quality reagents and the repeated use of media and reagents in in vitro toxicology studies.
The organ toxicity segment is expected to grow at a high CAGR
The toxicity endpoints and tests market, includes ADME; skin irritation, corrosion, and sensitization; genotoxicity; cytotoxicity; ocular toxicity; organ toxicity; phototoxicity; dermal toxicity; and other toxicity endpoints & tests. The organ toxicity segment is expected to grow at the highest CAGR during the forecast period due to factors such as the increasing focus on drug safety and consumer-product safety, along with the need to screen potential drug targets during the early stage of drug development.
By Toxicity Endpoints and Tests, ADME hold the largest market share in 2019
Based on toxicity endpoints and tests of in vitro toxicology testing, the market is subsegmented into ADME, genotoxicity, skin irritation and sensitization, cytotoxicity, ocular toxicity, organ toxicity, phototoxicity, dermal toxicity, and other toxicities (eco toxicity, endocrine disruption, and reproductive & developmental toxicity).
In 2019, the ADME segment is expected to account for the largest share of the global in vitro toxicology testing market owing to its highly reproducible & accurate data and the increasing demand to curb drug toxicity at the drug development phase.
Cell culture technology to hold the largest market share in 2019
Based on technology, the in vitro toxicology testing market is segmented into cell culture technologies, high-throughput technologies, cellular imaging technologies, and toxicogenomics. The toxicogenomics segment is expected to account for the highest CAGR in the global in the vitro toxicology testing market. Toxicogenomics is preferred to elucidate the changes in gene expression in response to toxic exposure and facilitates to identify toxicity pathways.
Asia Pacific is expected to grow at the highest rate in the in vitro toxicology testing market in 2019
The in vitro toxicology testing market in the Asia Pacific is estimated to grow at the highest CAGR during the forecast period. This is due to the emergence of CROs for outsourcing toxicology-related research projects, opposition to animal testing resulting in the use of alternate methods, increasing pharmaceutical drug pipeline, and growing consumer awareness of product safety, all of which are driving adoption of in vitro toxicology testing in the Asia Pacific.
Driver: Opposition to animal testing
Animal testing is a highly time-consuming process and involves high costs and immense safety risks for the animals involved. Working with rodent and rabbit models also increases the risk of zoonotic diseases. In 2004, the European Union passed legislation that prohibited the testing of finished cosmetic products on animals. It would be followed by a ban on testing cosmetic ingredients on animals in the European Union in 2009. This was further amended by forbidding the marketing of cosmetic products tested on animals. Complex toxicological endpoints, such as repeated-dose toxicity, reproductive toxicity, and toxicokinetics, were exempted from this ban.
Challenge: Derth of skilled professionals
IVT comprises sophisticated methods to study biological entities within a laboratory setup. It involves labor-intensive techniques to perform experiments and requires skilled professionals such as researchers and technicians to set up and run tests and experiments, make observations, obtain results, and analyze data. A lack of knowledge regarding the underlying scientific principles and the right choice of technique may result in several direct and indirect expenses and, thereby, increase the workload and time pressure on researchers and service providers. Thus, there is a need for highly skilled personnel for method development, validation, operation, and troubleshooting activities.
Key Market Players
The prominent players in the in vitro toxicology testing market include Thermo Fisher Scientific Inc. (US), Covance (US), Bio-Rad Laboratories, Inc. (US), GE Healthcare (US), Eurofins Scientific SE (Luxembourg), Merck KGaA (Germany), Charles River Laboratories International, Inc. (US), Catalent, Inc. (US), Cyprotex (UK), SGS S.A. (Switzerland), QIAGEN N.V. (Germany), Promega Corporation (US), Gentronix Limited (UK), BioIVT (US), and MB Research Laboratories (US).
By Product & Service
By Toxicity Endpoint & Test
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