Liquid Biopsy Market (By Application: Therapy Selection for Metastatic Breast Cancer (MBS), Therapy Selection for Other Metastatic Cancer, Molecular Health Monitoring; By Sample Type: Blood Sample based, Urine Sample based, Other Bio Fluids based; By Biomarker: Circulating Tumor Cells (CTC), Circulating Tumor DNA (ctDNA), Exosomes; By End-use: Multi-gene-parallel Analysis (NGS), Single Gene Analysis) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 2030

global liquid biopsy market size is expected to be worth around US$ 7.96 billion by 2030, according to a new report by Vision Research Reports.

The global liquid biopsy market size was valued at US$ 33.49 Million in 2020 and is anticipated to grow at a CAGR of 23.4% during forecast period 2021 to 2030.

Liquid Biopsy Market Size 2021 to 2030

Report Coverage

Report Scope Details
Market Size USD 7.96 billion by 2030
Growth Rate CAGR of 23.4% From 2021 to 2030
Base Year 2021
Forecast Period 2021 to 2030
Segments Covered Application, Sample Type, Biomarker, Technology 
Regional Scope North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Companies Mentioned

Guardant Health, Personal Genome Diagnostics, Biocept, Adaptive Biotechnologies, Cynvenio, NeoGenomics Laboratories, Qiagen, Trovagene, and RainDance Technologies.

Growth Factors

Enhanced view of tumor provided by liquid biopsy technology is estimated to augment the market in coming years.

While tissue biopsies have been standard for cancer diagnosis for past several year, their highly invasive nature and frequently associated complications have been major concerns. Moreover, these biopsies lead to high expenditure being incurred by patients. Liquid biopsies, on the other hand, offer a less invasive methodology along with high effectiveness. Thus, there are a number of key private organizations involved in rigorous R&D activities for liquid biopsy test development and it is only a matter of time before these procedures grow in prominence in diagnostic paraphernalia of oncologists and pathologists.

Report Highlights

Implications of complete commercialization of liquid biopsies are projected to be considerably disruptive. Three key applications of liquid biopsy can be a therapy selection tool for metastatic breast cancers, therapy selection for other metastatic cancers, and molecular health monitoring. With the rising incidence of metastatic cancer across the globe, the therapy selection tool for metastatic breast cancers segment is poised to hold a considerable share in the market throughout the forecast period.

Post the year 2020, once a considerable number of liquid biopsy products are commercialized, it is expected that liquid biopsy will find application not only in cancer diagnosis, but also as a molecular monitoring diagnostic tool for other diseases, which can be investigated using biofluids such as blood, CSF, urine and saliva for patient screening, cancer recurrences, and other associated prognosis.

Due to the numerous preexisting applications and methods for purification, blood sampling is the most frequently used sample for liquid biopsy studies and product developments. Cell-free DNA, circulating tumor cells, and exosomes as well as microvesicles can be detected in blood sample. This, in turn, results in higher adoption rate of liquid biopsy through blood sampling.

The next generation sequencing (NGS) technology is utilized herein for detection of multiple mutations in multiple genes. Results of certain studies and projects have indicated that saliva and plasma measurements are correlated, which thereby presents the possibility that non-invasive detection of oncogenic gene mutations in saliva is an emerging frontier. Moreover, this method of sampling offers benefits such as rapid assessment of patient health status for precise treatment of cancer.

On the basis of biomarker type, the liquid biopsy market has been divided into circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and exosomes (Macrovesicles with Protein, RNA, DNA). There are about 8-10 liquid biopsy tests based on CTCs and ctDNA that are currently commercialized. Furthermore, over 30 tests based on all three of these biomarkers are in clinical development by some key market participants such as Qiagen, Trovagene, and Biocept. Commercialization of these tests in the offing is estimated to benefit the growth of the overall market.

Circulating tumor cells tests are applicable in characterization of tumor cells through biochemical marker analysis. CTC isolation, detection, and molecular characterization systems find investigational application in prostate, breast, colon, head, neck, skin, lung, and pancreatic cancer.

Based on type of assay technology implemented for diagnosis, single gene analysis and multi gene analysis are the two methods employed. PCR-based sequencing is employed for analysis of mutations in disease specific genes whereas analysis of multiple diseases simultaneously can be carried out using the NGS multiplex testing. PCR microarray and NGS technology are both considered important for analysis of the aforementioned biomarkers to conduct any liquid biopsy analysis.

Multigene tests have taken clinical pharmacogenomics tests away from conventional sequencing of single genes and can be marked as a significant step towards comprehensive analysis of cancer genome. This technology aids oncologists in directing patients to targeted therapy by identification of genetic aberrations.

The market has been on a rise in most of the regions owing to growing prevalence of cancer and subsequently rising need for screening and increasing competition between various biotech firms to enter untapped markets around the world. Besides these, government grants for research institutes to innovate and improve available liquid biopsy testing methods are anticipated to back the growth of the market.

North America was at the forefront of the market in 2016, followed by Europe. The growth of the region can be attributed to recent regulatory approvals by CE for commercial use of these liquid biopsy tests. However, Asia Pacific is likely to register phenomenal CAGR during the forecast period as governments and companies are trying to keep growing cancer prevalence rates in the region in check. China, India, and Japan are the major contributing countries to the region’s growth.

Key Players

Guardant Health, Personal Genome Diagnostics, Biocept, Adaptive Biotechnologies, Cynvenio, NeoGenomics Laboratories, Qiagen, Trovagene, and RainDance Technologies.

Market Segmentation

  • Application Outlook

    • Therapy Selection for Metastatic Breast Cancer (MBS)

    • Therapy Selection for Other Metastatic Cancer

    • Molecular Health Monitoring

  • Sample Type Outlook 

    • Blood Sample based

    • Urine Sample based

    • Other Bio Fluids (Tissue fluids and Saliva) based

  • Biomarker Outlook 

    • Circulating Tumor Cells (CTC)

    • Circulating Tumor DNA (ctDNA)

    • Exosomes

  • Technology Outlook

    • Multi-gene-parallel Analysis (NGS)

    • Single Gene Analysis (PCR Microarrays)

  • Regional Outlook

    • North America

      • The U.S.

      • Canada

    • Europe

      • Germany

      • The U.K.

    • Asia Pacific

      • Japan

      • China

    • Latin America

      • Brazil

    • Middle East & Africa

      • South Africa

The Liquid Biopsy market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Liquid Biopsy market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Liquid Biopsy market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Liquid Biopsy market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Liquid Biopsy market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Liquid Biopsy capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Liquid Biopsy by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Liquid Biopsy market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Liquid Biopsy market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Liquid Biopsy market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Liquid Biopsy industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Liquid Biopsy market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Liquid Biopsy market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Liquid Biopsy market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Liquid Biopsy market. These factors have benefited the growth of the global market for Liquid Biopsy. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Liquid Biopsy. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Liquid Biopsy are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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