Long Read Sequencing Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2028

Published Date : Jan 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Long Read Sequencing market size is expected to be worth around US$ xx billion by 2028, according to a new report by Vision Research Reports.

The global Long Read Sequencing market size was valued at US$ 780.05 million in 2020 and is anticipated to grow at a CAGR of 23.10% during forecast period 2021 to 2028.

Growth Factors

Rapid advancements in third-generation long-read sequence analysis techniques are expected to bring a new era of research in the field of medical and biological sciences.

In addition, advantages offered by single-molecule real-time sequencing (SMRT) and Nanopore platforms over second-generation technologies are anticipated to enhance the adoption of these protocols. For instance, long reads generated by SMRT sequencers span across possible repetitive regions and provide a comprehensive view of the whole genome. Therefore, these technologies are adopted in the identification of genetic and structural variants.

Owing to the advantages offered by long-read technology, manufacturers are increasingly enhancing their product offerings to overcome technical as well as data analysis limitations. For instance, in January 2019, Oxford Nanopore Technologies launched NanoPipe, a web server for data analysis of nanopore MinION. The software is designed such that it can be easily used by wet-lab biologists with little knowledge about bioinformatics platforms as well as experienced bioinformaticians.

Report Highlights

The single-molecule real-time (SMRT) sequencing segment occupied a major market share as it helps in achieving high consensus accuracy owing to low systematic bias and longer read lengths. Moreover, SMRT does not require amplification during sample preparation. Therefore, it is adopted by researchers to span repetitive genomic regions and assemble genomes. In addition, SMRT technology provides more uniformity, reduces systematic errors, enables real-time observation of DNA polymerase activity and detects kinetic changes during sequencing analysis. Moreover, the technology is flexible to be used in a range of small or large projects to access multiple sample types with varying output lengths.

Consumables accounted for the largest market share in 2020. Consumables are to be procured at regular intervals by end users to carry out genome sequencing as these get used in multiple sequence runs. For instance, a single SMRT Cell is utilized per sequencing reaction. The services segment is expected to exhibit the highest CAGR during the forecast period. Key players such as Oxford Nanopore offer certification programs for their service providers to ensure high-quality service is offered through their platforms.

Instruments such as MinION, GridION, PromethION, PacBio RS System, and Sequel Systems are used to sequence DNA or its fragments for a wide range of applications in human genomics, cancer research, epigenetics, and transcriptome analysis. Advancements in computational hardware and software in these instruments are expected to propel market growth.

The identification and fine mapping of structural variation segment accounted for a major share in the long read sequencing market in 2018 as long reads enhance the sensitivity of detection of Structural Variations (SV). A research study carried out in 2019 indicates that the efficiency of detection of structural variations can be enhanced by seven times by the application of a multi-platform approach comprising long read sequencing technology. Efficient analysis of structural variants, breakpoints, and the entire SV event gets enhanced by the use of longer reads. In addition, longer reads facilitate efficient haplotype distinction and thereby enhance the accuracy of the analysis.

Sequencing accounted for the largest share in 2020 and is expected to dominate the overall market throughout the forecast period. This is majorly because it is one of the most important aspects of the workflow. Long read technology allows library preparation and real-time sequence analysis without the aid of PCR amplification. This removes PCR-related bias from the genome and allows researchers to study the genetic material in its native state. This enables long read technologies to detect methylation and other base modifications directly.

Academic research held the largest market share in 2020. This is due to the presence of a large number of biotechnology institutes that explore molecular biology and genome sequencing methodologies. In addition, growing usage of sequence analysis methodologies in research, academic workshops, and on-site bioinformatics courses offered by universities are expected to boost the academic research segment.

On the other hand, demand for advanced technologies for clinical diagnostics is regarded as a high impact rendering driver of the clinical research segment. Potential clinical implications of long read sequencing technology in clinical settings is expected to boost segment growth. Market participants are engaged in addressing existing challenges associated with the implementation of technology in order to incorporate the technique in clinical practice with a simplified laboratory workflow.

North America accounted for the largest share in 2020 owing to factors such as local presence of leading market players such as Pacific Biosciences, reputable informatics network, and well-regulated framework for usage and approval of genomic tests in the region. In addition, a rise in the number of genomic procedures for academic and clinical use in the U.S. is expected to drive the North America market throughout the forecast period. Asia Pacific is poised to witness the fastest growth throughout the forecast period. Growing penetration of leading players in emerging Asian markets and rising investments in design of advanced diagnostic methods will drive the regional market.

Key Players

Oxford Nanopore Technologies Limited; Pacific Biosciences of California, Inc.; Quantapore, Inc.; Stratos Genomics, Inc.; MicrobesNG; Institute of Integrative Biology of the Cell (I2BC); BaseClear B.V.; Future Genomics Technologies B.V.; Garvan Institute of Medical Research; Genome Transcriptome Facility of Bordeaux; NextOmics; and Takara Bio, Inc.

Market Segmentation

  • Technology Outlook

    • Single-Molecule Real-Time Sequencing (SMRT)

    • Nanopore Sequencing

  • Product Outlook

    • Instruments

    • Consumables

    • Services

  • Application Outlook

    • Identification & fine mapping of structural variation

    • Tandem Repeat Sequencing

    • Pseudogene discrimination

    • Resolving allele phasing

    • Reproductive genomics

    • Cancer

    • Viral & Microbial Sequencing

    • Others

  • Workflow Outlook 

    • Pre-sequencing

    • Sequencing

    • Data Analysis

  • End-use Outlook 

    • Academic Research

    • Clinical Research

    • Hospitals & Clinics

    • Pharma & Biotech Entities

    • Other

  • Regional Outlook

    • North America

      • The U.S.

      • Canada

    • Europe

      • Germany

      • The U.K.

    • Asia Pacific

      • Japan

      • China

    • Latin America

      • Brazil

    • MEA

      • South Africa

The Long Read Sequencing market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Long Read Sequencing market for the base year 2020 and the forecast between 2021 and 2028. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Long Read Sequencing market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Long Read Sequencing market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Long Read Sequencing market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Long Read Sequencing capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Long Read Sequencing by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Long Read Sequencing market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2028. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Long Read Sequencing market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Long Read Sequencing market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Long Read Sequencing industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Long Read Sequencing market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Long Read Sequencing market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Long Read Sequencing market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Long Read Sequencing market. These factors have benefited the growth of the global market for Long Read Sequencing. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Long Read Sequencing. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Long Read Sequencing are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2020
  • Forecast Year 2021 to 2028

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2028);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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