MiRNA Sequencing And Assay Market (By Product & Service: Products, Services; By Technology: Sequencing, Nanopore, Sanger, Single Molecule Real-time Seq; By Workflow: Library Preparation, Sequencing, Data Analysis & Storage; By Application: Cancer, Polyglutamine Diseases; By End-Use) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook and Forecast 2021-2030

Published Date : Jul 2021 | No. of Pages : 250+ Pages | Category : Healthcare

The global MiRNA Sequencing And Assay market size is expected to be worth around US$ 600.8 Mn by 2030, according to a new report by Vision Research Reports

The global MiRNA Sequencing And Assay market size was valued at US$ 224.8 Mn in 2020 and is anticipated to grow at a CAGR of 13.08% during forecast period 2021 to 2030.

Growth Factors

 Prominent players, such as Illumina, PerkinElmer, Qiagen, and others offer advanced miRNA sequencing products for multiple clinical applications. Moreover, these companies have collaborated with research institutes to expand the application of miRNA sequencing and assay in research studies.

The market holds a significant growth potential owing to the increasing application of miRNA sequencing and assay in the healthcare industry. For instance, several research studies demonstrate that miRNAs can be used as efficient biomarkers in the diagnosis and prognosis of cancer (breast, ovarian, cervical, and others), cardiovascular diseases, sepsis, and nervous system disorders. Therefore, miRNA sequence analysis is increasingly employed to analyze gene regulation in clinical disorders.

As plasma from COVID-19 recovered patients is rich in antiviral miRNAs and antibodies, it has been employed to treat SARS-CoV-2 infected patients. This has led to an increase in research studies that focus on the sequence analysis of miRNAs (microRNA) from the patient as well as the virus.

Report Highlights

 The product segment led the market and accounted for the largest revenue share of 80.9% in 2020 owing to the wide application of miRNA sequencing and assay in healthcare industries. Moreover, key players offer an extensive range of technologically advanced products in this segment. For instance, Illumina Inc. offers an extensive range of library preparation, sequencing instruments, accessories, consumables, and software and informatics for miRNA sequence analysis.

Moreover, ongoing extensive research to develop new products is likely to expand segment market share during the forecast period. For instance, researchers from the Université de Lyon developed BrumiR, an algorithm that can discover miRNAs exclusively and directly from sRNA-seq data. The results demonstrated by this toolkit were found to be much faster and more efficient.

The service segment is anticipated to grow at a lucrative rate in the market throughout the forecast period. Several prominent players offer services in miRNA sequencing and assay. Companies such as Eurofins Genomics, Arraystar Inc., Novogene Co., Ltd., Creative Biolabs, and others offer an extensive workflow for miRNA sequencing and assay.

The Sequencing by Synthesis (SBS) technology segment dominated the microRNA sequencing and assay market and accounted for the largest revenue share of 31.8% in 2020. The large share of the segment is attributed to the ongoing research and study in miRNA sequencing and assay by synthesis. According to a January 2021 study, researchers from Germany, China, and the U.S. evaluated the standard SBS and the approaches used for this. The study established that SBS recovered more annotated miRNAs, and generated more novel miRNAs.

Additionally, SBS technology is widely used to analyze and study several cancers and to develop personalized therapies. This is expected to contribute to a large share of the segment during the forecast period. Sequencing by Oligonucleotide Ligation and Detection (SOLiD) technology is known for its accuracy particularly when the coverage is more than 30x. Hence, it is extensively used in identifying variations in resequencing, transcriptome sequencing, and targeted resequencing. At Present, systems available in the market have 99.99% accuracy and 30 G per run of data output. Therefore, the SOLiD technology segment is anticipated to witness the fastest CAGR over the forecast period.

The sequencing workflow segment dominated the microRNA sequencing and assay market and accounted for the largest revenue share of 53.3% in 2020. Small RNA sequencing is becoming a popular approach to address multiple biological issues associated with the regulation of miRNAs and other small non-coding RNAs. miRNA, piRNA, and siRNA are the three most focused small RNAs and are extensively analyzed by sequencing since they have been identified to play a crucial role in the post-translational regulation of gene expression.

Additionally, sequence analysis helps to identify and analyze a complete range of miRNA and small RNA species. Furthermore, miRNA sequencing and assay also helps identify how post-transcriptional regulation affects phenotype and discover novel biomarkers, which has broad application in complex disease and cancer research. Illumina inc. platforms are the most popular instruments for miRNA sequence analysis, such as MiSeq and HiSeq.

The library preparation segment held the second-largest revenue share in the market in 2020. Companies like GENEWIZ offer library preparation services as a standalone service to customers and accelerate their in-house capabilities. GENEWIZ offers services for sequencing of the amplicon, RNA-Seq, exome, whole-genome, targeted resequencing, and cancer panels.

The cancer segment dominated the market and accounted for the largest revenue share of 36.0% in 2020. Dysregulated miRNAs have been studied as a new type of tumor suppressor gene or oncomiR which are playing important roles in cancer initiation and development. Aberrant expression of miRNAs shows great potential as cancer biomarkers with high sensitivity and specificity.

miRNAs play a crucial role in the regulation of hallmarks of cancer, such as apoptosis, proliferation, invasion, metastasis, and stemness in tumors. Many miRNAs are identified as biomarkers for breast cancer for diagnosis and indicators of prognosis. Furthermore, the active participation of several global organizations, such as the National Cancer Institute, National Foundation for Cancer Research, Cancer Research Institute, and Cancer Research U.K., in cancer research is expected to positively influence the progress of this vertical over the forecast period.

The polyglutamine diseases application segment is expected to register the fastest CAGR over the forecast period. Particular expression patterns of miRNA in the brain parenchyma and circulating fluids and have been identified as potential biomarkers for prognosis and diagnosis of polyglutamine disease.

The research and academic institutes segment dominated the market and accounted for the largest revenue share of 54.9% in 2020. Several academic institutes are taking initiative to accelerate research related to miRNA sequencing and assay. For instance, the University of Manchester researchers have created a database of miRNAs that have become an important resource in academia and the biotechnology industry.

The data empowers the construction of experimental kits and resources that support experimental microRNA research across academic and industrial settings, which ultimately benefits product development, drug discovery, and clinical research. The pharmaceutical and biotechnology industry segment is expected to witness a substantial CAGR over the forecast period. Companies such as Regulus Therapeutics are involved in the development of miRNA-based therapeutics. Rising investments to develop techniques and tools to overcome existing challenges in the clinical translation of miRNA sequencing and assay applications are likely to supplement segment growth.

North America dominated the miRNA sequencing and assay market and accounted for the largest revenue share of 46.1% in 2020. This can be attributed to the local presence of a significant number of key players, such as Illumina Inc., Thermo Fisher Scientific, PerkinElmer, Inc., and others. The increase in research and development spending by major players to develop innovative and advanced products in the U.S. is expected to drive regional growth. For instance, in 2020 Illumina, Inc. spent USD 682 million on research and development to develop new sequence analysis technology and upgrade existing technology.

The presence of several associations and organizations operating in this region that take initiatives to spread awareness about new advanced miRNA sequencing products and technology drive regional growth. Additionally, miRNA sequencing and assay are significantly adopted by clinics, healthcare networks, military, and agriculture laboratories that receive support through government funding. Thus, supportive government laws and investments are contributing to the regional market growth.

Key Players

 

  • Thermo Fisher Scientific, Inc.

  • Illumina, Inc.

  • QIAGEN

  • PerkinElmer, Inc.

  • Abcam plc

  • New England Biolabs

  • Takara Bio Inc.

  • Lexogen GmbH

  • Norgen Biotek Corp

  • Maravai LifeSciences

  • HTG Molecular Diagnostics, Inc.

  • Meridian Bioscience, Inc.

  • System Biosciences, LLC

Market Segmentation

 

  • Product & Service Outlook (Revenue, USD Million, 2017 - 2028)

    • Products

      • Library Preparation Kits

      • Sequencing Consumables

      • Instruments

    • Services

  • Technology Outlook (Revenue, USD Million, 2017 - 2028)

    • Sequencing (Seq.) By Synthesis

    • Seq. By Oligonucleotide Ligation and Detection (SOLiD)

    • Nanopore Seq.

    • Sanger Seq.

    • Single Molecule Real-time (SMRT) Seq.

  • Workflow Outlook (Revenue, USD Million, 2017 - 2028)

    • Library Preparation

    • Sequencing

    • Data Analysis & Storage

  • Application Outlook (Revenue, USD Million, 2017 - 2028)

    • Cancer

    • Polyglutamine Diseases

    • Autoimmune Disease

    • Schizophrenia

    • Others

  • End-use Outlook (Revenue, USD Million, 2017 - 2028)

    • Pharmaceutical & Biotechnology Industry

    • Research and Academic Institutes

    • Contract Research Organizations

  • Regional Outlook (Revenue, USD Million, 2017 - 2028)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • France

      • U.K.

      • Italy

      • Spain

    • Asia Pacific

      • China

      • Japan

      • India

      • Australia

      • South Korea

    • Latin America

      • Brazil

      • Mexico

    • Middle East Africa (MEA)

      • South Africa

      • Saudi Arabia

The MiRNA Sequencing And Assay market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of MiRNA Sequencing And Assay market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global MiRNA Sequencing And Assay market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the MiRNA Sequencing And Assay market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted MiRNA Sequencing And Assay market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the MiRNA Sequencing And Assay capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of MiRNA Sequencing And Assay by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global MiRNA Sequencing And Assay market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major MiRNA Sequencing And Assay market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of MiRNA Sequencing And Assay market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the MiRNA Sequencing And Assay industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The MiRNA Sequencing And Assay market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to MiRNA Sequencing And Assay market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of MiRNA Sequencing And Assay market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new MiRNA Sequencing And Assay market. These factors have benefited the growth of the global market for MiRNA Sequencing And Assay. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for MiRNA Sequencing And Assay. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of MiRNA Sequencing And Assay are as follows:

·         Historic Year: 2017-2020

·         Base Year: 2021

·         Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

·         To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);

·         Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.

·         Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

·         To define, describe and forecast the market by type, application and region.

·         To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.

·         To identify significant trends and factors driving or inhibiting the market growth.

·         To analyze the opportunities in the market for stakeholders by identifying the high growth segments.

·         To strategically analyze each submarket with respect to individual growth trend and their contribution to the market

·         To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

To strategically profile the key players and comprehensively analyze their growth strategies.


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