Next Generation Sequencing Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2030

Published Date : Feb 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Next Generation Sequencing market size is expected to be worth around US$ 11.10 billion by 2030, according to a new report by Vision Research Reports.

The global Next Generation Sequencing market size was valued at US$ 4.05 billion in 2020 and is anticipated to grow at a CAGR of 14.6% during forecast period 2021 to 2030.

Growth Factors

As researchers are continuously unlocking the genetic diversity, the development of targeted therapies is on the rise. These therapies are targeted towards narrow populations of patients that have specific or rare genomic. Therefore, this is expected to increase the utilization of next generation sequencing (NGS) technology for targeted therapies.

Simplification in the NGS workflow coupled with the continued price reductions in instruments as well as reagents is attributed to the increasing adoption of this technology. The cost of sequencing the human genome has reduced from USD 100 million to less than USD 1,000 in less than two decades. Moreover, enhancement in the bioinformatics capabilities will lead to broadening of NGS adoption at the low- and high-throughput ends of the research market.

Several companies are engaged in the innovation of long-read sequencing technologies, which will augment the research as well as clinical application sets. The growing automation in the pre- & post-sequencing protocols, and data analysis is also driving the market. The utilization of novel platforms for the development of personalized medicine at a genetic level is also a significant factor, which is expected to boost the demand for NGS over the forecast period.

Report Highlights

Oncology accounted for the largest revenue of over 28% in 2020. Next generation sequencing (NGS) coupled with bioinformatics tools holds potential in revolutionizing oncology research, diagnosis, and treatment. Advancements in NGS technology have led to improvements in cancer research indicating the dawn of the “molecular age” of cancer.

Leading companies, such as Illumina, are constantly working toward the development of NGS-based In Vitro Diagnostic (IVD) solutions for cancer diagnostics. For instance, in January 2021, Illumina collaborated with Myriad Genetics to develop a kit-based version of the latter’s myChoice companion diagnostic (CDx) test. This combines NGS technology with companion diagnostics to enhance the genomic profiles of tumor samples.

Several other market players also offer NGS solutions to support cancer research. For example, in January 2021, Merus N.V.; a clinical-stage immuno-oncology company; collaborated with National Cancer Center, Japan, and Erasmus University Medical Center, the Netherlands to evaluate its HER2/3-targeting bispecific antibody in solid tumors. Under this, Merus plans to support access to NGS testing for non-small cell lung, and pancreatic cancer.

Targeted sequencing & resequencing dominated the NGS market in 2020 with a revenue share of over 73%. The technology offers economical alternatives for WGS and facilitates the in-depth investigation of genomic regions. RNA-based targeted sequencing is anticipated to witness lucrative growth in the coming years as a result of the rising demand for differential expression analysis.

Moreover, wide use of the Amplicon RNA-Seq technology for the targeted RNA sequencing for the diagnosis of schizophrenia and other disorders supports the growth. Availability of expression kits for apoptosis, cardiotoxicity, cell cycle, p450 & p53 pathway, cardiotoxicity, and other customized panels is anticipated to fuel segment growth in the coming years.

The WGS technology is anticipated to grow at a significant rate from 2021 to 2028. A rise in the use of WGS to combat Covid-19 is attributed to segment growth. Moreover, companies, such as Illumina, offer microbial WGS in the market as the first NGS method that can be used for infectious disease surveillance. Such technology can produce high data quality and rapid results. Furthermore, it can be used to identify, track, and respond to disease outbreaks in a region.

The sequencing segment accounted for the dominant revenue share of more than 54% in 2020 as sequencing is a critical step of the workflow. In addition, sequencing is a capital-intensive procedure and thus accounts for a higher revenue generation. With an expected increase in the implementation of WGS, the subsequent data generation from sequencing projects is expected to grow. Due to the large volumes of data generated after sequencing, analysis becomes a challenge. However, there are several tools available in the market that address these issues.

For instance, Illumina’s BaseSpace Suite helps analyze sequencing data and produces results in a short span. The company has also acquired DRAGEN Bio-IT Platform (DRAGEN), and Edico Genome to expand its data analysis offerings. Other companies, such as Genomatix and DNAnexus, offer cloud-based platforms for the analysis and management of large volumes of sequencing data.

The academic research end-use segment held the largest share of more than 53% in 2020. The segment is projected to expand further at a steady CAGR from 2021 to 2028. This growth can be attributed to the application of NGS solutions in research projects that are carried out in universities and research centers. Furthermore, scholarships offered for Ph.D. projects in NGS are anticipated to drive demand for NGS products and services, thereby resulting in lucrative growth over the coming years.

Moreover, countries, such as Germany and the U.K., have several universities that offer NGS applications and molecular biology courses. For instance, the Wageningen University & Research, the Netherlands offers NGS facilities and technologies that can be used in various applications. The university uses instruments and platforms, such as Illumina HiSeq2500, MiSeq, and PacBio Sequel.

Clinical research is expected to be the fastest-growing end-use segment from 2021 to 2028. This can be attributed to the rising penetration of NGS-based diagnostic tests that are CLIA-waived and under the process of clinical approval augmenting the demand for NGS solutions. In addition, commercially available clinical research solutions from Agilent, Illumina, Thermo Fisher Scientific, and other companies for target enrichment & detection are anticipated to provide this segment with high growth opportunities over the forecast period.

North America dominated the global market with a revenue share of 49.77% in 2020. The presence of several clinical laboratories that use NGS to offer genetic testing services drives the regional market. In addition, the development and launch of novel products by key companies in North America boost the market growth. For instance, in August 2020, Quest Diagnostics launched Automated NGS Engine to power AncestryHealth, a consumer genetics offering by Ancestry. The platform offers genetic screening of risks for blood disorders, colon cancer, breast cancer, and heart diseases.

Asia Pacific is expected to be the fastest-growing regional market from 2021 to 2028. The presence of local companies, such as BGI Genomics, and NGS service providers including First BASE Laboratories Sdn Bhd, Macrogen Asia Pacific Pte Ltd., and others is expected to drive the market in the Asia Pacific. MedGenome Labs Ltd. offers NGS services to more than 5,500 clinicians and 1,600 hospitals across South Asia and India.

Key Players

  • Illumina


  • Thermo Fisher Scientific, Inc.

  • F. Hoffman-La Roche Ltd.

  • Oxford Nanopore Technologies

  • Genomatix GmbH

  • PierianDx

  • DNASTAR, Inc.

  • Eurofins GATC Biotech GmbH

  • Perkin Elmer, Inc.

  • BGI

  • Bio-Rad Laboratories, Inc.

Market Segmentation

  • Technology Outlook

    • WGS

    • Whole Exome Sequencing

    • Targeted Sequencing & Resequencing

      • DNA-based

      • RNA-based

  • Application Outlook 

    • Oncology

      • Diagnostics and Screening

        • Oncology Screening

          • Sporadic Cancer

          • Inherited Cancer

        • Companion Diagnostics

        • Other Diagnostics

      • Research Studies

    • Clinical Investigation

      • Infectious Diseases

      • Inherited Diseases

      • Idiopathic Diseases

      • Non-Communicable/Other Diseases

    • Reproductive Health

      • NIPT

        • Aneuploidy

        • Microdeletions

      • PGT

      • Newborn Genetic Screening

      • Single Gene Analysis

    • HLA Typing/Immune System Monitoring

    • Metagenomics, Epidemiology & Drug Development

    • Agrigenomics & Forensics

    • Consumer Genomics

  • Workflow Outlook 

    • Pre-Sequencing

      • NGS Library Preparation Kits

      • Semi-automated Library Preparation

      • Automated Library Preparation

      • Clonal Amplification

    • Sequencing

    • NGS Data Analysis

      • NGS Primary Data Analysis

      • NGS Secondary Data Analysis

      • NGS Tertiary Data Analysis

  • End-use Outlook 

    • Academic Research

    • Clinical Research

    • Hospitals & Clinics

    • Pharma & Biotech Entities

    • Other Users

  • Regional Outlook 

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

      • Italy

      • Spain

      • France

    • Asia Pacific

      • Japan

      • China

      • South Korea

      • Australia

      • India

    • Latin America

      • Brazil

      • Mexico

    • Middle East Africa

      • South Africa

      • Saudi Arabia

The Next Generation Sequencing market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Next Generation Sequencing market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Next Generation Sequencing market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Next Generation Sequencing market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Next Generation Sequencing market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Next Generation Sequencing capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Next Generation Sequencing by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Next Generation Sequencing market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Next Generation Sequencing market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Next Generation Sequencing market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Next Generation Sequencing industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Next Generation Sequencing market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Next Generation Sequencing market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Next Generation Sequencing market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Next Generation Sequencing market. These factors have benefited the growth of the global market for Next Generation Sequencing. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Next Generation Sequencing. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Next Generation Sequencing are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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