Nucleic Acid Isolation And Purification Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2030

Published Date : Mar 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Nucleic Acid Isolation And Purification market size is expected to be worth around US$ 10.8 billion by 2030, according to a new report by Vision Research Reports.

The global Nucleic Acid Isolation And Purification market size was valued at US$ 4.4 billion in 2020 and is anticipated to grow at a CAGR of 11.7% during forecast period 2021 to 2030.

Growth Factors

The growth can be primarily attributed to the technological advancements in molecular detection platforms. The technologies such as robotic liquid handling in automated DNA extraction systems, have improved the process flow. Such automation has streamlined all the tasks involved in various processes, such as DNA extraction from samples, serial dilution, and picking the desired gene of interest.

The outbreak of SARS-CoV-2 in late 2019 in China quickly translated into a global pandemic, which led to high demand for efficient and affordable diagnostic tests that could be carried out in non-clinical as well as clinical settings. This also led to high demand for nucleic acid extraction kits which in turn has led the key players to increase their manufacturing capabilities. For instance, in March 2020, QIAGEN announced the expansion of its production capacity in the U.S. and Europe to reach 20 million monthly patient tests by the end of 2020.

Moreover, rapid diagnosis, effective treatment options, and future prevention plans are essential in the management of COVID-19. The current race for the development of cost-effective, point-of-contact test kits and efficient laboratory methodologies for the detection of coronavirus infection has driven a new frontier of diagnostic innovation. The increase in adoption of PCR for SARS-CoV-2 detection by a wide range of commercial laboratories drives the market, as nucleic acid isolation and purification is an important step in the PCR workflow. 

Report Highlights

The kits and reagents segment dominated the market for nucleic acid isolation and purification in 2020 and accounted for the largest revenue share of 76.0%. The wide-scale application of kits and reagents for DNA and RNA isolation for preparing samples and libraries can be primarily attributed to market growth. In addition, a rising number of research studies focused on understanding rare and common genome-based diseases are increasingly using kits and reagents, which is further driving the segment.

The instruments segment is expected to witness the fastest CAGR of 12.6% over the forecast period. The growth in the segment can be attributed to the launch of new instruments facilitating automation, rapid technological innovation, and growing demand for automated Nucleic Acid Isolation and Purification (NAIP) instruments.

For instance, in April 2020, Thermo Fisher Scientific, Inc. collaborated with Hamilton Company to develop an automated nucleic acid extraction platform for forensic laboratory purposes. The ID NIMBUS Presto assay facilitates automated DNA extraction from samples collected from the crime scene.

The RNA isolation and purification segment dominated the market for nucleic acid isolation and purification and accounted for the largest revenue share of 53.6% in 2020 owing to the increasing application in COVID-19 diagnostics and rise in use of purified mRNA for the construction of the cDNA library. These libraries have various applications such as gene expression profiling, sequencing, and clinical diagnostics. Moreover, the availability of a broad range of kits for extraction and processing of viral and bacterial RNA is further contributing to segment growth.

DNA isolation and purification is expected to witness lucrative growth of 13.5% during the forecast period owing to its increasing application in gene expression profiling. In addition, pharmaceutical and biotechnology companies are undertaking various strategic initiatives such as the launch of new products for efficiently carrying out nucleic acid isolation steps.

For instance, in February 2020, Promega Corporation launched its Wizard HMW DNA Extraction Kit. The kit helped researchers in working with large DNA fragments, facilitating steady performance during long-read sequencing applications.

Viral DNA extraction and purification is increasingly gaining attention for their therapeutic and diagnostic applications. For instance, they are used as vectors for gene therapy and nanobiological weapons for fighting other viruses. The utilization of viral DNA in the market is henceforth gaining momentum through the coming years.

The magnetic beads segment dominated the market for nucleic acid isolation and purification and accounted for the largest revenue share of 37.9% in 2020 and is expected to continue the trend in the coming years. The growing adoption of magnetic beads is owing to the advantage that it provides researchers and scientists with improved assay performance and better isolation and purification of DNA and RNA.

In recent years, functionalized magnetic beads have been used along with suitable buffer systems for rapid and efficient extraction. This method reduces the requirement of centrifugation that usually results in the breaking of nucleic acids. Hence, such a positive aspect of this technology provides automated extraction with minimal requirement of centrifugation for nucleic acid isolation steps.

Column-based techniques are expected to witness substantial CAGR through the forecast period. Silica columns are extensively preferred for obtaining higher quality nucleic acids in a short time. In addition, these techniques can be incorporated in microchips and spin columns that have several advantages such as cost-effectivity, fast organic extraction, and compatibility with automated instruments. Hence, such methods are widely adopted in nucleic acid isolation methods.

The diagnostics segment accounted for the largest revenue share of 34.3% in 2020. The large share of the segment can be attributed to the rising application of DNA and RNA isolation for the identification of pathogens in routine sample processing. For instance, PCR techniques are widely adopted for the rapid detection of microorganisms, which was previously not possible with traditional microbiological detection methods.

Moreover, companies are launching new diagnostic solutions for identifying emerging infections and diseases. For instance, in February 2021, ThermoFisher Scientific, Inc. launched Applied Biosystems TaqPath COVID–19 HT Kit to conduct COVID-19 diagnostic assay. This product is a high-throughput version of the company’s TaqPath COVID-19 CE-IVD RT-PCR Kit. Hence, the launch of new products for diagnosing various new emerging infections is further contributing to segment growth. 

The drug discovery and development segment is expected to witness a lucrative growth rate of 12.1% over the forecast period. Growth in the segment can be primarily attributed to robust investments in pharmaceutical and biotechnology companies for the development of novel drugs. Nucleic acid purification methods are largely employed in various steps of drug discovery, target identification, and testing.

The hospitals and diagnostic centers segment dominated the market for nucleic acid isolation and purification and accounted for the largest revenue share of 33.6% in 2020 owing to increasing demand for early and accurate diagnosis of diseases. DNA/RNA isolation and purification techniques are considered efficient tools for the diagnosis of even genetic diseases such as sickle cell anemia, hemophilia A, and Tay-Sachs disease. Hence, the availability of such efficient technologies at moderate to low prices is expected to increase their adoption rate in diagnostic centers and hospitals.

Pharmaceutical and biotechnology companies are anticipated to witness the fastest growth rate of 11.8% during the forecast period. The rapid adoption of emerging technologies by companies for the development of various therapies is anticipated to fuel market growth. As nucleic acid isolation and purification is the initial step for manufacturing various drugs and therapies, it will certainly drive the adoption of instruments and kits associated with conducting these processes.

North America dominated the market for nucleic acid isolation and purification and held the largest revenue share of 36.7% in 2020. The presence of established players and their efforts in developing technologically advanced rapid purification and isolation devices is the major contributor to market growth in the region. In addition, the rising funding initiatives for biotechnology research are further propelling the growth of the market in the region.

Asia Pacific is the fastest-growing region in the nucleic acid isolation and purification market. The factors contributing to the growth of the market in the region include rising economic growth, extensive research in life sciences, growing patient population, supportive government initiatives, and the presence of various innovative biotech companies in the region.

Key Players

  • QIAGEN

  • Thermo Fisher Scientific, Inc.

  • Illumina, Inc.  

  • Danaher

  • F. Hoffmann-La Roche AG

  • Merck KGaA

  • Agilent Technologies

  • Bio-Rad Laboratories, Inc.

  • Takara Bio, Inc.

  • Promega Corporation

  • New England Biolabs

  • LGC Limited

  • Abcam plc

  • Norgen Biotek Corp

  • AutoGen, Inc.

  • Biogenuix

  • PCR Biosystems, Inc.

  • MagGenome

  • Apical Scientific Sdn. Bhd

  • MACHEREY-NAGEL GmbH & Co. KG

Market Segmentation

  • Product Outlook 

    • Kits & Reagents

    • Instruments

  • Type Outlook 

    • DNA Isolation & Purification

      • Genomic DNA Isolation & Purification

      • Plasmid DNA Isolation & Purification

      • Viral DNA Isolation & Purification

      • Other

    • RNA Isolation & Purification

      • miRNA Isolation & Purification

      • mRNA Isolation & Purification

      • Total RNA Isolation & Purification

      • Other

  • Method Outlook 

    • Column-based

    • Magnetic Beads

    • Reagent-based

    • Others

  • Application Outlook 

    • Precision Medicine

    • Diagnostics

    • Drug Discovery & Development

    • Agriculture and Animal Research

    • Other Applications

  • End-use Outlook 

    • Academic Research Institutes

    • Pharmaceutical & Biotechnology Companies

    • Contract Research Organizations

    • Hospitals and Diagnostic Centers

    • Other End-use

  • Regional Outlook 

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • China

      • Japan

    • Latin America

      • Brazil

      • Mexico

    • Middle East and Africa (MEA)

      • South Africa

The Nucleic Acid Isolation And Purification market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Nucleic Acid Isolation And Purification market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Nucleic Acid Isolation And Purification market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Nucleic Acid Isolation And Purification market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Nucleic Acid Isolation And Purification market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Nucleic Acid Isolation And Purification capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Nucleic Acid Isolation And Purification by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Nucleic Acid Isolation And Purification market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Nucleic Acid Isolation And Purification market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Nucleic Acid Isolation And Purification market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Nucleic Acid Isolation And Purification industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Nucleic Acid Isolation And Purification market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Nucleic Acid Isolation And Purification market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Nucleic Acid Isolation And Purification market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Nucleic Acid Isolation And Purification market. These factors have benefited the growth of the global market for Nucleic Acid Isolation And Purification. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Nucleic Acid Isolation And Purification. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Nucleic Acid Isolation And Purification are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

To strategically profile the key players and comprehensively analyze their growth strategies.


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