Oligonucleotide Synthesis Market Size, Share, Trends, Growth, Consumption, Revenue, Company Analysis and Forecast 2020-2027

Published Date : Nov 2020 | No. of Pages : 200 Pages | Category : Healthcare

According to Vision Research Reports, the global a market size is projected to surpass around at US$ 4.6 billion by 2027 and expected to expand at a CAGR of 9.7% from 2020 to 2027.

Increasing use of synthesized oligonucleotides in diagnostics and research applications, and Technological advancements in synthetic chemistry are projected to drive the global oligonucleotide synthesis market during the forecast period.


  • An oligonucleotide is a single-stranded chain composed of a number of nucleoside units connected together by the process of phosphodiesterase, which typically synthesizes small fragments on nucleic acid sequences up to 25 bases, with the desired structure and a given sequence needed for different applications.An oligonucleotide is a single-stranded chain composed of a number of nucleoside units connected together by the process of phosphodiesterase, which typically synthesizes small fragments on nucleic acid sequences up to 25 bases, with the desired structure and a given sequence needed for different applications.
  • There are various lengths of oligonucleotides, and sequences and design modifications available. Thanks to the increasingly developing biotechnology and life sciences markets, there has been a n ever-rising need for oligonucleotides on the global market, as well as rising acceptance and use of oligonucleotides in clinical and diagnostic fields.

Technological Advancements in Synthetic Chemistry to Drive Market

  • The advances in the technological development of organic molecules are expected to drive the growth of the oligonucleotide synthesis market
  • The advanced synthesis of oligonucleotides provides longer oligos with better sequence fidelity and higher purity that can be used in a number of molecular biology applications
  • Various pharmaceutical and biotechnology companies are continuously  working on developing newer and advanced methods in synthetic chemistry
  • For instance, Integrated DNA Technologies, leader of synthesized oligonucleotides has developed various pioneered methods to synthesize oligonucleotides of extreme lengths. The company has developed oligonucleotides up to 200 base length which is used with mass spectrometry for the manufacture of mini-genes.

Synthesized oligonucleotides Segment to Dominate Market

  • Based on product type, the global oligonucleotide synthesis market has been divided into reagents & consumables, equipment, and synthesized oligonucleotides. The synthesized oligonucleotides segment has been bifurcated into DNA oligonucleotides, RNA oligonucleotides, and others.
  • The synthesized oligonucleotides segment dominated the global oligonucleotide synthesis market in 2019 and the trend is projected to continue during the forecast period. Synthesized oligonucleotides are widely used in research as well as in therapeutics and diagnostics applications. Synthesized oligonucleotides are ready to use oligonucleotides. These are also available as customized oligos prepared as per need. There are two types of commercially used synthesized oligonucleotide: DNA oligonucleotides and RNA oligonucleotides. Bridged Nucleic Acid (BNA) and Locked Nucleic acid (LNA) are the other types of synthesized oligonucleotides used in research.

Research Applications to be Highly Lucrative Segment

  • In terms of application, the global oligonucleotide synthesis market has been classified into research, diagnostic and therapeutic. Among the applications, the research applications segment dominated the global oligonucleotide synthesis market in 2019. Rising R&D focus of pharmaceutical & biotechnology companies, along with technological advances in the techniques such as polymerase chain reaction, and next generation sequencing, are some of the major factors driving the growth of the research segment in 2019. However, rising applications in therapeutics, and growing R&D in RNAi therapeutic drugs is expected to drive the growth of the therapeutic segment during 2020-2027

North America to Dominate Global Market

  • In terms of region, the global oligonucleotide synthesis market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global Oligonucleotide Synthesis market in 2019, followed by Europe.
  • North America accounted for major share of the global oligonucleotide synthesis market in 2019, According to the data obtained from the ongoing clinical trials in the oligonucleotides segment, there were more than 70 oligonucleotide ongoing or recently completed trials in the U.S. alone. Fast growing life science industry, rising focus on genetics and genomics in the research and diagnostics applications in North America, and growing focus of pharmaceutical organizations on oligonucleotides as therapeutic agents comprising RNAi and antisense therapeutics are driving demand for oligonucleotides in North America.
  • However, rising focus on personalized medicine and growing biotechnology and life science research activities in Asia Pacific, along with rising healthcare spending on research & development in India, China, and Japan are factors expected to boost the growth of the market for oligonucleotide synthesis in Asia Pacific from 2020 to 2027.

Competitive Landscape

  • The global oligonucleotide synthesis market is fragmented in terms of number of players. Key players in the global market include GE Healthcare, Thermo Fischer Scientific, Agilent Technologies, Inc., Merck KGaA, Integrated DNA Technologies, Inc., Kaneka Eurogentec S.A., BioAutomation, Gene Design, Inc., Eurofins Genomics, and ATDBio, Ltd. among others.

Market Segmentation

By Product Type

    • Reagents & Consumables
    • Equipment
    • Synthesized Oligos
      • DNA Oligonucleotides
      • RNA Oligonucleotides
      • Others

By Applications

    • Research
      • Polymerase Chain Reaction
      • Next Generation Sequencing
      • Others
    • Therapeutics
      • Antisense Oligonucleotides
      • Nucleic Acid Aptamers
    • Diagnostic

By End User

    • Biotech & Pharma Companies
    • Research Inst.
    • Diagnostic Labs

By Region

    • North America
      • U.S.
      • Canada
    • Europe
      • Germany
      • U.K.
      • France
      • Italy
      • Spain
      • Rest of Europe
    • Asia Pacific          
      • China
      • India
      • Japan
      • Australia & New Zealand
      • Rest of Asia Pacific
    • Latin America
      • Brazil
      • Mexico
      • Rest of Latin America
    • Middle East & Africa
      • GCC Countries
      • South Africa
      • Rest of Middle East & Africa

Report Scope

The Oligonucleotide synthesis market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Oligonucleotide synthesis market for the base year 2020 and the forecast between 2020 and 2027. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Oligonucleotide synthesis market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Oligonucleotide synthesis market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Oligonucleotide synthesis market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Oligonucleotide synthesis capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Oligonucleotide synthesis by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Oligonucleotide synthesis market. These figures have been provided in terms of both revenue and volume for the period 2016 to 2027. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Oligonucleotide synthesis market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Oligonucleotide synthesis market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Oligonucleotide synthesis industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

Oligonucleotide synthesis market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Oligonucleotide synthesis market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Oligonucleotide synthesis market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Oligonucleotide synthesis market. These factors have benefited the growth of the global market for Oligonucleotide synthesis. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Oligonucleotide synthesis. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Oligonucleotide synthesis are as follows:

  • History Year: 2016-2019
  • Base Year: 2020
  • Forecast Year 2020 to 2027

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2016-2019) and forecast (2020-2027);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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