The global organoids market was valued over US$ 1.8 Bn in 2020 and is predicted to reach over US$ 12.7 billion by 2030.
Organoids are replicated or miniaturized versions of organs such as stomach, liver, lung, kidney, and brain produced from stems cells in vitro. These miniature models are three-dimensional tissue culture derived from stem cells. The stem cells are derived from pluripotent and organ specific stem cells. The global organoids market is driven by rise in prevalence of various diseases, sudden outbreak of infectious diseases in 2020, and development of organoid models for studying various disease modeling, which are expected to boost the organoids market during the forecast period. Technological advancements leading to the development of organoids for diagnosis and studying patient-derived tumors.
Increase in incidence and prevalence of chronic and infectious diseases, adoption of organoids as therapeutics tools, application of organoids in drug discovery & personalized medicine, and use of organoids in research & development is anticipated to propel the global organoids market. The globe market is driven by the application of organoids as an important tool for cell biology, gene therapy, regenerative medicine, cancer research, and disease modelling. Technological advancements are expected to propel the global organoids market during the forecast period.
Organoids are miniature, self-organized three-dimensional culture derived from stem cells, including pluripotent stem cells and adult stem cells. Organoids are considered replication of complex organs such as stomach, intestine, brain, kidney, lungs, and liver. Organoids are grown from stem cells of different sources, and these cells divide indefinitely and produce different types of cells. These structures resemble the miniature organs, which range from size of a hair width to five millimeters.
Organoids provide scientists a detailed understanding and view about the organ growth and formation, and offer them promising approach about the disease pathology and human development. Scientists have found organoids to be potential mini organs in the drug discovery and personalized medicine.
Organoids as Therapeutic Tools to Drive Global Market
Organoids are considered prominent tools for discovery of drugs, diagnosis, and development of treatment for various chronic diseases. Rise in prevalence and increase in incidence of various diseases drive scientists and researchers to continue research on organoid models to study human physiology and disease modeling. Organoids are considered innovative approach for drug discovery, disease modeling through stem cell research, and innovating personalized medicines. These factors enable faster adoption of organoids as therapeutic tools across the globe. Amidst the COVID-19 pandemic, researchers are using organoids as prominent tools to study the coronavirus disease, modelling, and development of treatment. Organoids are considered powerful tools for respiratory diseases or infections. These factors are anticipated to propel the global organoids market.
Increasing Demand for Gene Mutation and Cancer Research to Drive Market
Over the past decade, organoids are being increasingly used in a range of applications, including disease modeling, pathogenesis, drug screening, and regenerative medicine, and the trend is set to continue during the forecast period. Organoid technologies have witnessed considerable developments in recent years, and continue to pave the way for the development of in vitro physiologic systems that model the origin tissues with high degree of accuracy compared to conventional approaches. The increasing focus on research and development activities is expected to play a key role in the development of the global organoids market during the assessment period.
The capability of 3D-organoid cultures to mimic organ functionality to some degree is one of the key factors likely to establish organoids as an ideal model for applications such as stem cell research to precision medicine. Furthermore, the increasing adoption of the organoid technology for use in a range of applications, including genetic mutation, gene assessment, and tumor modelling is expected to accelerate the overall development of the global organoids market during the assessment period. The assessment of different diseases by leveraging the organoid technology is anticipated to remain one of the most prominent applications of organoids in the upcoming years.
Increasing Demand for Tumor Modelling and Biobanking to Propel Market Growth
The consistent progress in the organoid technology has gradually paved the way for ‘tumouroids’ and patient-centric 3D cultures of cells that are isolated from tumor biopsies. Over the past few decades, tumouroid lines have been established from a plethora of cancer types such as liver, breast, prostate, brain, bladder, and more from metastasis as well as primary tumors. Due to consistent advancements, in the current scenario, tumouroid lines are increasingly being passed in vitro, which opens up new avenues for a range of downstream applications. Moreover, 3D-based cultures offer additional advantages over the conventional 2D cancer-derived cell lines. Moreover, research and development activities have indicated that tumouroid culturing is highly efficient in enabling the collection of various cancer subtypes from a large pool of patients. As organoids can be easily derived and expanded from single cancer cells, the adoption of organoids to mimic intratumour diversification in culture is on the rise– a factor that is projected to propel the global organoids market during the assessment period.
New Discoveries Driven by Research & Development to Boost Prospects
Research and development activities are set to play a key role in the overall development of the global organoids market during the assessment period. In addition, increasing collaborations between researchers and medical experts are anticipated to accelerate the development of complex organoids. For instance, two recent discoveries are expected to boost the overall prospects of next-generation organoid development. The new research collaboration between a team of scientists from the Cincinnati Children’s and Japan was announced in August 2020. As per the research team, discoveries from the new research collaboration are likely to be one of the most critical aspects for the development of a new wave of complex organoids. Although the organoid technology has progressed at a consistent pace over the past few years, the application of the same continues to remain sluggish in the current scenario. However, increasing focus on the commercialization of organoids and consistent progress in genome editing techniques are expected to bolster the growth of the global organoids market during the assessment period.
The global organoids market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global organoids market in 2019, followed by Europe and Asia Pacific. The presence of prominent players conducting various studies using organoid models is a major factor boosting the growth of the organoids market in North America. In April 2020, STEMCELL Technologies, Inc. conducted projects in alliance with the University of British Columbia (UBC) at Genome British Columbia for testing thousands of FDA-approved drugs and clinical stage compounds alone or in combination for drug repurposing against SARS-CoV-2 infection by using human organoid culture technology.
The organoids market in Europe is anticipated to expand at a high CAGR from 2020 to 2030. The presence of key players offering organoids, technological advancements, large patient pool, increase in the geriatric population, and rise in prevalence of chronic diseases are anticipated to boost the growth of the organoids market in the region. Moreover, the company offers innovative portfolio of organoid models for drug screening, development of regenerative medicine, personalized medicine, and other therapeutic application. This is expected to fuel the growth of the organoids market in Europe during the forecast period.
The global organoids market is consolidated in terms of number of players. The market is dominated by key players with innovative product offerings, robust geographic presence, and large investments in research & development. Leading players operating in the global organoids market include STEMCELL Technologies Inc., Cellesce Ltd., Hubrecht Organoid Technology, Definigen, 3Dnamics, Inc., Organoid Therapeutics, PeproTech, Inc., Thermo Fisher Scientific, Corning Incorporated (Life Sciences), and Merck KGgA. Prominent players have introduced innovative organoid models amidst the COVID-19 pandemic to study the disease pathology and develop innovative treatment. Moreover, companies are investing in continuous research & development for wide therapeutic applications.
In February 2020, Cellesce Ltd. published application of patient-derived organoids in the early cancer drug discovery, which would offer significant benefits to cancer patients. The company invests in continuous research and development for identifying tumor derived organoid as a novel solution for the drug discovery and its benefits in the cancer research.
Scope of the Report
VRR’s report on the global organoids market studies the past as well as current growth trends and opportunities to gain valuable insights of these indicators for the market during the forecast period from 2020 to 2030. The report provides the overall revenue of the global organoids market for the period 2018–2030, considering 2021 as the base year and 2030 as the forecast year. The report also provides the compound annual growth rate (CAGR) for the global organoids market for the forecast period.
The report has been prepared after an extensive research. Primary research involved bulk of research efforts, wherein analysts carried out interviews with industry leaders and opinion makers. Secondary research involved referring to key players’ product literature, annual reports, press releases, and relevant documents to understand the global organoids market.
Secondary research also included Internet sources, statistical data from government agencies, websites, and trade associations. Analysts also employed a combination of top-down and bottom-up approaches to study various phenomena in the global organoids market.
The report comprises an elaborate executive summary, along with a snapshot of the growth behavior of various segments and sub-segments included in the scope of the study. Additionally, the report sheds light on changing competitive dynamics in the global organoids market. These indices serve as valuable tools for existing market players as well as for entities interested in participating in the global organoids market. The next section of the global organoids market report highlights the USPs, which include increase in incidence & prevalence of diseases, including infectious and other chronic disease, adoption of organoids in the research & development, technological advancements, and COVID-19 pandemic impact on the global organoids market.
The report delves into the competition landscape of the global organoids market. Key players operating in the global organoids market have been identified, and each one of these has been profiled for distinguishing business attributes. Company overview, financial standings, recent developments, and SWOT are some of the attributes of players profiled in the global organoids market report.
Key Questions Answered in Organoids Market Report
Research Objectives and Research Approach
The comprehensive report on the global organoids market begins with an overview of the market, followed by the scope and objectives of the study. Following this, the report provides detailed explanation of the objectives of the study and healthcare compliances laid down by accredited agencies in the purview of research in the global organoids market. It is followed by market introduction, market dynamics, and an overview of the global organoids market, which includes TMR analysis of market drivers, restraints, and trends affecting the growth of the market. Furthermore, Y-o-Y analysis with elaborate insights has been provided to understand the Y-o-Y trends of the global organoids market. The next section of the global organoids market report highlights the USPs, which includes increase in incidence and prevalence of diseases, including infectious and other chronic conditions, adoption of organoids in the research & development, technological advancements, and COVID-19 pandemic impact on the global organoids market.
For reading comprehensibility, the report has been compiled in a chapter-wise layout with each section divided into smaller ones. The report comprises an exhaustive collection of graphs and tables that are appropriately interspersed in the compilation. Pictorial representation of actual and projected values of key segments is visually appealing to readers. This also allows comparison of market shares of key segments in the past and at the end of the forecast period.
Revenue generated by key product manufacturers has been mapped to ascertain the size of the global organoids market in terms of value. The forecast presented here assesses the total revenue generated in the global organoids market. In order to provide an accurate forecast, we initiated by sizing up the current organoids market with the help of the parent market.
The report analyzes the global organoids market in terms of type, application, source, and region. Key segments under each criteria have been studied at length, and the market share for each of these at the end of 2030 has been provided. These valuable insights would help market stakeholders in making informed business decisions for investments in the global organoids market.
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