Prosthetic disc nucleus market size surpassed at US$ 96 Mn in 2020 and to reach US$ 193 million by 2030 with a CAGR of 8.4% during the forecast period 2021 to 2030.
Increase in incidence of spine disorder across the globe, surge in global geriatric population, and rise in the demand for minimally invasive surgeries are expected to drive the global market during the forecast period.
The market growth will be driven by the increasing prevalence of degenerative back diseases, advancements in gene therapies, tissue engineering, and cell therapy, and research and development activities. Research and development activities will play a key role in the overall development of the global prosthetic disc nucleus market. Market players should focus on mergers & acquisitions and product launch to gain a competitive edge in the current prosthetic disc nucleus market landscape.
Prosthetic disc nucleus is hydrogel-based spinal implant used as an adjunct treatment for patients with degenerative disc disorder and herniation, where surgical intervention is the only option. Prosthetic disc nucleus offers an alternative, cost-effective, and minimally invasive procedure to total disc replacement. In 1996, C.D. Ray introduced the first PDN device, which was the first nucleus replacement device designed to replace the functions of the disc that were lost through degeneration. The global prosthetic disc nucleus market is driven by rise in prevalence of spine disorders across globe, increase in global geriatric population, and high demand for minimally invasive surgeries across the globe.
North America dominated the global prosthetic disc nucleus market in 2019, followed by Europe, and the trend is anticipated to continue during the forecast period. The region’s dominance can be ascribed to the high prevalence and rise in incidence rates of degenerative disc disorder, well-established healthcare industry, and increase in geriatric population in the region.
Key Drivers
High Prevalence and Rising Incidence of Spine Disorders to Drive Global Market
The increase in incidence of spinal disorders, such as degenerative disc diseases and spinal stenosis, has fueled the usage of spine implants. An estimated 266 million people are affected with lumbar degenerative spine disorder and low back pain each year. According to Hebrew SeniorLife Institute for Aging Research, around one-third of people aged between 40 and 59 are affected with moderate to severe degenerative disc disorder and around half of the population is affected with moderate to severe osteoarthritis. The prevalence of disc height narrowing and joint osteoarthritis increased by 2 to 4 times in people aged between 60 and 69 years and 70 and 89 years, respectively. Disorders of the spine are an important health and social issue, as these are major contributors to disability globally. Respondents often report a spine disorder as lower back pain, irrespective of the actual diagnosis or cause of the condition. Thus, high prevalence and rise in incidence rate of spine disorder across the globe is a prominent factor projected to boost the prosthetic disc nucleus market during the forecast period.
Progress in Treatment of Degenerative Disc Diseases to Aid Market Growth
The prevalence of lower back pain is one of the major problem in individuals of all age groups. While in most cases, back pain can be treated using conventional physiotherapy and medication, early intervention for the treatment of degenerative disc diseases is imperative. Over the past couple of decades, minimally invasive procedures and regenerative medicines have garnered immense popularity and the adoption is expected to further rise in comparison with existing surgical procedures. Advancements in cell-based, bio-molecular, and gene therapies are expected to provide a plethora of opportunities to the players involved in the current prosthetic disc nucleus market.
The promise offered by non-invasive therapies, including prosthetic disc nucleus, is set to fuel the overall growth of the global prosthetic disc nucleus market during assessment period. However, high costs of implants and overall procedure are expected to pose as a barrier to market growth.
COVID-19 Pandemic to Hinder Market Growth
The onset of the novel COVID-19 pandemic is projected to have a strong impact on the overall growth of the global prosthetic disc nucleus market in 2020. Due to stringent lockdowns, restrictions on trade and transportation and increasing focus on curbing the spread of the novel COVID-19 infection, the demand for steeply priced prosthetic disc nucleus has witnessed a decline in 2020. Furthermore, supply chains of raw materials have been severely disrupted due to the transportation restrictions, thereby impacting the overall production of prosthetic disc nucleus. Due to this, the market growth is likely to remain slower than initial projections.
Prominent Regions
In terms of region, the global prosthetic disc nucleus market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global prosthetic disc nucleus market in 2019, followed by Europe. The U.S. dominated the prosthetic disc nucleus market in North America in 2019, due to the presence of key players, technological advancements, adoption of minimally invasive surgeries, and adequate reimbursement policies. This, in turn, is estimated to boost the market in the region. The prosthetic disc nucleus market in Asia Pacific is likely to expand at a notable CAGR from 2020 to 2030. The expansion of the market in the region can be attributed to the adoption of new technologies, high awareness, significant healthcare spending, early availability of advanced technologies, and penetration of research activities across the region.
Strategic Acquisitions and Collaborations by Key Players to Drive Global Market
The global prosthetic disc nucleus market is consolidated in terms of number of players. The market is dominated by key players with strong geographic presence. Key players operating in the global prosthetic disc nucleus market include Stryker Corporation, Zimmer Biomet Holdings, Inc, DePuy Synthes (Johnson & Johnson), NuVasive, Inc, and Orthofix International N.V. In March 2018, Orthofix International N.V. acquired Spinal Kinetics, Inc., a leading developer and manufacturer of cervical and lumbar disc devices. The spinal kinetics product portfolio comprises M6-C cervical and M6-L lumbar artificial discs for patients with degenerative disc disorders. In November 2018, Xian Janssen (Janssen Global Services, LLC) and Ali Health signed a strategic cooperation agreement to establish a new model of Internet health services. Johnson & Johnson's pharmaceutical subsidiary Xian Yangsen Pharmaceutical Co., Ltd. (Janssen Global Services, LLC) announced that it is working with Alibaba Group's flagship platform in the field of medical health.
Market Segmentation
By Surgery Type
By End User
By Region
Scope of the Report
VRR’s report on the global prosthetic disc nucleus market studies past as well as current growth trends and opportunities to gain valuable insights of these indicators for the market during the forecast period, 2020 to 2030 The report provides the overall value (US$ Mn) of the global prosthetic disc nucleus market for the period 2018–2030, considering 2020 as the base year and 2030 as the forecast year. The report also provides the compound annual growth rate (CAGR) for the global prosthetic disc nucleus market for the forecast period.
The report has been prepared after an extensive research. Primary research involved bulk of research efforts, wherein analysts carried out interviews with industry leaders and opinion makers. Extensive secondary research involved referring to key players’ product literature, annual reports, press releases, and relevant documents to understand the global prosthetic disc nucleus market.
Secondary research also included Internet sources, statistical data from government agencies, websites, and trade associations. Analysts also employed a combination of the top-down and bottom-up approaches to study various phenomena in the global prosthetic disc nucleus market.
The report comprises an elaborate executive summary, along with a snapshot of the growth behavior of various segments and sub-segments included in the scope of the study. Additionally, the report sheds light on changing competitive dynamics in the global prosthetic disc nucleus market. These indices serve as valuable tools for existing market players as well as for entities interested in participating in the global prosthetic disc nucleus market. The next section of the global prosthetic disc nucleus market report highlights the USPs, which include disease prevalence and incidence rate of degenerative spine diseases, and impact of COVID-19 on the global prosthetic disc nucleus market.
The report delves into the competition landscape of the global prosthetic disc nucleus market. Key players operating in the global prosthetic disc nucleus market have been identified, and each one of these has been profiled for distinguishing business attributes. Company overview, financial standings, recent developments, and SWOT are some of the attributes of players profiled in the global prosthetic disc nucleus market report.
Key Questions Answered in Global Prosthetic Disc Nucleus Market Report
Research Objectives and Research Approach
The comprehensive report on the global prosthetic disc nucleus market begins with an overview of the market, followed by the scope and objectives of the study. Following this, the report provides detailed explanation of the objectives of the study and health care compliances laid down by accredited agencies in the purview of research in the global prosthetic disc nucleus market. It is followed by market introduction, market dynamics, and an overview of the global prosthetic disc nucleus market, which includes VRR analysis of market drivers, restraints, and trends affecting the growth of the market. Furthermore, Y-o-Y analysis with elaborate insights has been provided to understand the Y-o-Y trends of the prosthetic disc nucleus market.
For reading comprehensibility, the report has been compiled in a chapter-wise layout, with each section further divided into smaller sections. The entire report comprises an exhaustive collection of graphs and tables that are appropriately interspersed in the entire compilation. Pictorial representation of actual and projected values of key segments is visually appealing to readers. This also allows comparison of the market shares of key segments in the past and at the end of the forecast period.
Revenue generated by key prosthetic disc nucleus manufacturers has been mapped to ascertain the size of the global prosthetic disc nucleus market in terms of value. The forecast presented here assesses the total revenue generated in the prosthetic disc nucleus market. In order to provide an accurate forecast, we initiated by sizing up the current prosthetic disc nucleus market with the help of the parent market.
The report analyzes the global prosthetic disc nucleus market in terms of surgery type, end user, and region. Key segments under each criteria have been studied at length, and the market share for each of these at the end of 2030 has been provided. These valuable insights would help market stakeholders in making informed business decisions for investments in the global prosthetic disc nucleus market.
Table of Contents
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary
4. Market Overview
4.1. Introduction
4.1.1. Market Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Prosthetic Disc Nucleus Market Analysis and Forecast, 2018–2030
4.4.1. Market Revenue Projections (US$ Mn)
5. Key Insights
5.1. Disease Prevalence and Incidence Rate of Degenerative Spine Diseases
5.2. COVID-19 Pandemics Impact on Global Prosthetic Disc Nucleus Market
6. Global Prosthetic Disc Nucleus Market Analysis and Forecast, by Surgery Type
6.1. Introduction & Definition
6.2. Key Findings / Developments
6.3. Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
6.3.1. Minimally Invasive Spine Surgery
6.3.2. Open Spine Surgery
6.4. Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type
7. Global Prosthetic Disc Nucleus Market Analysis and Forecast, by End-user
7.1. Introduction & Definition
7.2. Key Findings / Developments
7.3. Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
7.3.1. Hospitals
7.3.2. Ambulatory Surgery Centers
7.3.3. Others
7.4. Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user
8. Global Prosthetic Disc Nucleus Market Analysis and Forecast, by Region
8.1. Key Findings
8.2. Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Region
8.2.1. North America
8.2.2. Europe
8.2.3. Asia Pacific
8.2.4. Latin America
8.2.5. Middle East & Africa
8.3. Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by Region
9. North America Prosthetic Disc Nucleus Market Analysis and Forecast
9.1. Introduction
9.1.1. Key Findings
9.2. North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
9.2.1. Minimally Invasive Spine Surgery
9.2.2. Open Spine Surgery
9.3. North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
9.3.1. Hospitals
9.3.2. Ambulatory Surgery Centers
9.3.3. Others
9.4. North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country, 2018–2030
9.4.1. U.S.
9.4.2. Canada
9.5. North America Prosthetic Disc Nucleus Market Attractiveness Analysis
9.5.1. By Surgery Type
9.5.2. By End-user
9.5.3. By Country
10. Europe Prosthetic Disc Nucleus Market Analysis and Forecast
10.1. Introduction
10.1.1. Key Findings
10.2. Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
10.2.1. Minimally Invasive Spine Surgery
10.2.2. Open Spine Surgery
10.3. Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
10.3.1. Hospitals
10.3.2. Ambulatory Surgery Centers
10.3.3. Others
10.4. Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
10.4.1. Germany
10.4.2. U.K.
10.4.3. France
10.4.4. Spain
10.4.5. Italy
10.4.6. Rest of Europe
10.5. Europe Prosthetic Disc Nucleus Market Attractiveness Analysis
10.5.1. By Surgery Type
10.5.2. By End-user
10.5.3. By Country/Sub-region
11. Asia Pacific Prosthetic Disc Nucleus Market Analysis and Forecast
11.1. Introduction
11.1.1. Key Findings
11.2. Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
11.2.1. Minimally Invasive Spine Surgery
11.2.2. Open Spine Surgery
11.3. Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
11.3.1. Hospitals
11.3.2. Ambulatory Surgery Centers
11.3.3. Others
11.4. Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
11.4.1. China
11.4.2. India
11.4.3. Japan
11.4.4. Australia & New Zealand
11.4.5. Rest of Asia Pacific
11.5. Asia Pacific Prosthetic Disc Nucleus Market Attractiveness Analysis
11.5.1. By Surgery Type
11.5.2. By End-user
11.5.3. By Country/Sub-region
12. Latin America Prosthetic Disc Nucleus Market Analysis and Forecast
12.1. Introduction
12.1.1. Key Findings
12.2. Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
12.2.1. Minimally Invasive Spine Surgery
12.2.2. Open Spine Surgery
12.3. Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
12.3.1. Hospitals
12.3.2. Ambulatory Surgery Centers
12.3.3. Others
12.4. Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
12.4.1. Brazil
12.4.2. Mexico
12.4.3. Rest of Latin America
12.5. Latin America Prosthetic Disc Nucleus Market Attractiveness Analysis
12.5.1. By Surgery Type
12.5.2. By End-user
12.5.3. By Country/Sub-region
13. Middle East & Africa Prosthetic Disc Nucleus Market Analysis and Forecast
13.1. Introduction
13.1.1. Key Findings
13.2. Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
13.2.1. Minimally Invasive Spine Surgery
13.2.2. Open Spine Surgery
13.3. Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
13.3.1. Hospitals
13.3.2. Ambulatory Surgery Centers
13.3.3. Others
13.4. Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
13.4.1. GCC Countries
13.4.2. South Africa
13.4.3. Rest of Middle East & Africa
13.5. Middle East & Africa Prosthetic Disc Nucleus Market Attractiveness Analysis
13.5.1. By Surgery Type
13.5.2. By End-user
13.5.3. By Country/Sub-region
14. Competitive Landscape
14.1. Market Player – Competition Matrix (By Tier and Size of companies)
14.2. Company Share Analysis
14.3. Company Profiles
14.3.1. Stryker Corporation
14.3.1.1Company Overview (HQ, Business Segments, Employee Strength)
14.3.1.2.Financial Overview
14.3.1.3.Product Portfolio
14.3.1.4.Strategic Overview
14.3.1.5.SWOT Analysis
14.3.2. Zimmer Biomet Holdings, Inc.
14.3.2.1.Company Overview (HQ, Business Segments, Employee Strength)
14.3.2.2.Financial Overview
14.3.2.3.Product Portfolio
14.3.2.4.Strategic Overview
14.3.2.5.SWOT Analysis
14.3.3. DePuy Synthes (Johnson & Johnson)
14.3.3.1. Company Overview (HQ, Business Segments, Employee Strength)
14.3.3.2.Financial Overview
14.3.3.3.Product Portfolio
14.3.3.4.Strategic Overview
14.3.3.5.SWOT Analysis
14.3.4. NuVasive, Inc.
14.3.4.1.Company Overview (HQ, Business Segments, Employee Strength)
14.3.4.2.Financial Overview
14.3.4.3.Product Portfolio
14.3.4.4.Strategic Overview
14.3.4.5.SWOT Analysis
14.3.5. Orthofix International N.V.
14.3.5.1.Company Overview (HQ, Business Segments, Employee Strength)
14.3.5.2.Financial Overview
14.3.5.3.Product Portfolio
14.3.5.4.Strategic Overview
14.3.5.5.SWOT Analysis
14.3.6. Replication Medical, Inc.
14.3.6.1. Company Overview (HQ, Business Segments, Employee Strength)
14.3.6.2.Financial Overview
14.3.6.3.Product Portfolio
14.3.6.4.Strategic Overview
14.3.6.5.SWOT Analysis
14.3.7. Spine Wave, Inc.
14.3.7.1. Company Overview (HQ, Business Segments, Employee Strength)
14.3.7.2.Financial Overview
14.3.7.3.Product Portfolio
14.3.7.4.Strategic Overview
14.3.7.5.SWOT Analysis
Cross-segment Market Size and Analysis for
Mentioned Segments
Additional Company Profiles (Upto 5 With No Cost)
Additional Countries (Apart From Mentioned Countries)
Country/Region-specific Report
Go To Market Strategy
Region Specific Market DynamicsRegion Level Market Share Import Export AnalysisProduction AnalysisOthers