Protein Crystallization Market (By Type: Consumables, Reagents Kits, Instruments; By Technology; By Application; By End-user) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook and Forecast 2022-2030

The global protein crystallization market size was estimated at around USD 1.2 billion in 2021 and it is projected to hit around USD 2.63 billion by 2030, growing at a CAGR of 9.1% from 2022 to 2030.

Protein Crystallization Market Size 2021 to 2030

Crystallization is the process of the formation of 3D structured molecule from a liquid substance. Protein crystallization is the process of the formation of pure and saturated protein crystals containing millions of protein molecules arranged in an orderly manner. The proteins are dissolved in the aqueous sample solution until they become supersaturated. For this purpose, the methods such as microdialysis, and diffusion are used. Crystallization of proteins is also a technique for purification. These crystallized proteins are used for X-ray crystallography.

Scope of The Report

Report Coverage Details
Market Size in 2021 USD 1.2 billion
Revenue Forecast by 2030 USD 2.63 billion 
Growth rate from 2022 to 2030 CAGR of 9.1%
Base Year 2021
Forecast Period 2022 to 2030
Segmentation Type, Technology, Application, End user, Region 
Companies Covered

Rigaku Corporation, Hampton Research Corp, HiMedia Laboratories, Bruker Corporation, Thermo Fisher Scientific, Inc., Jena Bioscience GmbH, Agilent Technologies, Charles River Laboratories, Inc., Molecular Dimensions Ltd., Formulatrix, Inc., MiTeGen LLC

 

Following are the steps of protein crystallization:-

  • Characterization: Proteins are purified and characterized using CD spectroscopy. This is done to study the structure, activity, and stability of protein which completes the process of crystallography.
  • Crystallization: Supersaturated protein solutions are formed with the help of salts and buffers. Large pure protein crystals are formed and subjected to X-ray crystallography.

The important applications of crystallization are:-

1. Medical chemistry via studying the structural biology (study of drug receptor interaction to improve drug efficacy),

2. Developing, scaling up, purification, and separation of therapeutic proteins,

3. Formulation and drug delivery.

The rise in infectious diseases has boosted the demand for the production and development of therapeutic products and vaccine development. Therapeutic proteins have a wide range of applications in treating cancer. The increasing prevalence of cancer disease spurs the market growth.

The increasing number of product launches and increasing efforts to find the solution for the diagnosis and treatment of chronic diseases by the biotechnology and pharmaceutical industries also has a positive impact on the market. In July 2022, Redwire Corporation announced that it would develop new manufacturing techniques for the development of small pharmaceutical protein crystals and other molecules for R&D and production. The high resolution imaging of the crystal structures provides the precise results which fuels the crystallization market. However, a lack of qualified researchers for handling crystallization protocol can hamper the market growth.

The crystallization market is segmented based on type, technology, application, end-use, and region. The type segment is further segmented into consumables, reagent kits, instruments, software, and services. The technology segment is divided into small-angle X-ray scattering, X-ray crystallography, cryo-electron microscopy, NMR spectroscopy. The application segment is divided into therapeutic protein production, drug delivery, and medical chemistry. End use segment is classified into pharmaceutical companies, biotechnology companies, and others.

Based on regional analysis the market is segmented into North America, Europe, Asia-Pacific, Latin America, the Middle East, and Africa. North America holds the major share in crystallization market. This is due to the increase in R&D investments and collaboration by the major key players in this region. Also, the increased government funding for proteomic research and the development of structure-based drugs enhances the market growth. Asia Pacific and Europe also have high investments in the R&D sector by the key players of pharmaceutical and biotechnology company which boost the crystallization technology.

Major companies operating in the protein crystallization market include Rigaku Corporation, Hampton Research Corp, HiMedia Laboratories, Bruker Corporation, Thermo Fisher Scientific, Inc., Jena Bioscience GmbH, Agilent Technologies, Charles River Laboratories, Inc., Molecular Dimensions Ltd., Formulatrix, Inc., MiTeGen LLC among others.

Market Segmentation

By Type Outlook

  • Consumables
  • Reagent Kits
  • Instruments 
    • Liquid Handling Instruments
    • Crystal Imaging Instruments
  • Software and Services

By Technology Outlook

  • X-ray Crystallography
  • NMR Spectroscopy
  • Cryo-electron Microscopy
  • Small-angle X-ray Scattering (SAXS)

By Application Outlook

  • Therapeutic protein production
  • Drug delivery
  • Medical chemistry
  • Others

By End user Outlook

  • Pharmaceutical Company
  • Biotechnology Company
  • Others

By Region Outlook

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East And Africa

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Protein Crystallization Market 

5.1. COVID-19 Landscape: Protein Crystallization Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

Chapter 6. Market Dynamics Analysis and Trends

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Protein Crystallization Market, By Type

8.1. Protein Crystallization Market, by Type, 2022-2030

8.1.1. Consumables

8.1.1.1. Market Revenue and Forecast (2017-2030)

8.1.2. Reagent Kits

8.1.2.1. Market Revenue and Forecast (2017-2030)

8.1.3. Instruments

8.1.3.1. Market Revenue and Forecast (2017-2030)

8.1.4. Software and Services

8.1.4.1. Market Revenue and Forecast (2017-2030)

Chapter 9. Global Protein Crystallization Market, By Technology

9.1. Protein Crystallization Market, by Technology, 2022-2030

9.1.1. X-ray Crystallography

9.1.1.1. Market Revenue and Forecast (2017-2030)

9.1.2. NMR Spectroscopy

9.1.2.1. Market Revenue and Forecast (2017-2030)

9.1.3. Cryo-electron Microscopy

9.1.3.1. Market Revenue and Forecast (2017-2030)

9.1.4. Small-angle X-ray Scattering (SAXS)

9.1.4.1. Market Revenue and Forecast (2017-2030)

Chapter 10. Global Protein Crystallization Market, By Application 

10.1. Protein Crystallization Market, by Application, 2022-2030

10.1.1. Therapeutic protein production

10.1.1.1. Market Revenue and Forecast (2017-2030)

10.1.2. Drug delivery

10.1.2.1. Market Revenue and Forecast (2017-2030)

10.1.3. Medical chemistry

10.1.3.1. Market Revenue and Forecast (2017-2030)

10.1.4. Others

10.1.4.1. Market Revenue and Forecast (2017-2030)

Chapter 11. Global Protein Crystallization Market, By End user 

11.1. Protein Crystallization Market, by End user, 2022-2030

11.1.1. Pharmaceutical Company

11.1.1.1. Market Revenue and Forecast (2017-2030)

11.1.2. Biotechnology Company

11.1.2.1. Market Revenue and Forecast (2017-2030)

11.1.3. Others

11.1.3.1. Market Revenue and Forecast (2017-2030)

Chapter 12. Global Protein Crystallization Market, Regional Estimates and Trend Forecast

12.1. North America

12.1.1. Market Revenue and Forecast, by Type (2017-2030)

12.1.2. Market Revenue and Forecast, by Technology (2017-2030)

12.1.3. Market Revenue and Forecast, by Application (2017-2030)

12.1.4. Market Revenue and Forecast, by End user (2017-2030)

12.1.5. U.S.

12.1.5.1. Market Revenue and Forecast, by Type (2017-2030)

12.1.5.2. Market Revenue and Forecast, by Technology (2017-2030)

12.1.5.3. Market Revenue and Forecast, by Application (2017-2030)

12.1.5.4. Market Revenue and Forecast, by End user (2017-2030)

12.1.6. Rest of North America

12.1.6.1. Market Revenue and Forecast, by Type (2017-2030)

12.1.6.2. Market Revenue and Forecast, by Technology (2017-2030)

12.1.6.3. Market Revenue and Forecast, by Application (2017-2030)

12.1.6.4. Market Revenue and Forecast, by End user (2017-2030)

12.2. Europe

12.2.1. Market Revenue and Forecast, by Type (2017-2030)

12.2.2. Market Revenue and Forecast, by Technology (2017-2030)

12.2.3. Market Revenue and Forecast, by Application (2017-2030)

12.2.4. Market Revenue and Forecast, by End user (2017-2030)

12.2.5. UK

12.2.5.1. Market Revenue and Forecast, by Type (2017-2030)

12.2.5.2. Market Revenue and Forecast, by Technology (2017-2030)

12.2.5.3. Market Revenue and Forecast, by Application (2017-2030)

12.2.5.4. Market Revenue and Forecast, by End user (2017-2030)

12.2.6. Germany

12.2.6.1. Market Revenue and Forecast, by Type (2017-2030)

12.2.6.2. Market Revenue and Forecast, by Technology (2017-2030)

12.2.6.3. Market Revenue and Forecast, by Application (2017-2030)

12.2.6.4. Market Revenue and Forecast, by End user (2017-2030)

12.2.7. France

12.2.7.1. Market Revenue and Forecast, by Type (2017-2030)

12.2.7.2. Market Revenue and Forecast, by Technology (2017-2030)

12.2.7.3. Market Revenue and Forecast, by Application (2017-2030)

12.2.7.4. Market Revenue and Forecast, by End user (2017-2030)

12.2.8. Rest of Europe

12.2.8.1. Market Revenue and Forecast, by Type (2017-2030)

12.2.8.2. Market Revenue and Forecast, by Technology (2017-2030)

12.2.8.3. Market Revenue and Forecast, by Application (2017-2030)

12.2.8.4. Market Revenue and Forecast, by End user (2017-2030)

12.3. APAC

12.3.1. Market Revenue and Forecast, by Type (2017-2030)

12.3.2. Market Revenue and Forecast, by Technology (2017-2030)

12.3.3. Market Revenue and Forecast, by Application (2017-2030)

12.3.4. Market Revenue and Forecast, by End user (2017-2030)

12.3.5. India

12.3.5.1. Market Revenue and Forecast, by Type (2017-2030)

12.3.5.2. Market Revenue and Forecast, by Technology (2017-2030)

12.3.5.3. Market Revenue and Forecast, by Application (2017-2030)

12.3.5.4. Market Revenue and Forecast, by End user (2017-2030)

12.3.6. China

12.3.6.1. Market Revenue and Forecast, by Type (2017-2030)

12.3.6.2. Market Revenue and Forecast, by Technology (2017-2030)

12.3.6.3. Market Revenue and Forecast, by Application (2017-2030)

12.3.6.4. Market Revenue and Forecast, by End user (2017-2030)

12.3.7. Japan

12.3.7.1. Market Revenue and Forecast, by Type (2017-2030)

12.3.7.2. Market Revenue and Forecast, by Technology (2017-2030)

12.3.7.3. Market Revenue and Forecast, by Application (2017-2030)

12.3.7.4. Market Revenue and Forecast, by End user (2017-2030)

12.3.8. Rest of APAC

12.3.8.1. Market Revenue and Forecast, by Type (2017-2030)

12.3.8.2. Market Revenue and Forecast, by Technology (2017-2030)

12.3.8.3. Market Revenue and Forecast, by Application (2017-2030)

12.3.8.4. Market Revenue and Forecast, by End user (2017-2030)

12.4. MEA

12.4.1. Market Revenue and Forecast, by Type (2017-2030)

12.4.2. Market Revenue and Forecast, by Technology (2017-2030)

12.4.3. Market Revenue and Forecast, by Application (2017-2030)

12.4.4. Market Revenue and Forecast, by End user (2017-2030)

12.4.5. GCC

12.4.5.1. Market Revenue and Forecast, by Type (2017-2030)

12.4.5.2. Market Revenue and Forecast, by Technology (2017-2030)

12.4.5.3. Market Revenue and Forecast, by Application (2017-2030)

12.4.5.4. Market Revenue and Forecast, by End user (2017-2030)

12.4.6. North Africa

12.4.6.1. Market Revenue and Forecast, by Type (2017-2030)

12.4.6.2. Market Revenue and Forecast, by Technology (2017-2030)

12.4.6.3. Market Revenue and Forecast, by Application (2017-2030)

12.4.6.4. Market Revenue and Forecast, by End user (2017-2030)

12.4.7. South Africa

12.4.7.1. Market Revenue and Forecast, by Type (2017-2030)

12.4.7.2. Market Revenue and Forecast, by Technology (2017-2030)

12.4.7.3. Market Revenue and Forecast, by Application (2017-2030)

12.4.7.4. Market Revenue and Forecast, by End user (2017-2030)

12.4.8. Rest of MEA

12.4.8.1. Market Revenue and Forecast, by Type (2017-2030)

12.4.8.2. Market Revenue and Forecast, by Technology (2017-2030)

12.4.8.3. Market Revenue and Forecast, by Application (2017-2030)

12.4.8.4. Market Revenue and Forecast, by End user (2017-2030)

12.5. Latin America

12.5.1. Market Revenue and Forecast, by Type (2017-2030)

12.5.2. Market Revenue and Forecast, by Technology (2017-2030)

12.5.3. Market Revenue and Forecast, by Application (2017-2030)

12.5.4. Market Revenue and Forecast, by End user (2017-2030)

12.5.5. Brazil

12.5.5.1. Market Revenue and Forecast, by Type (2017-2030)

12.5.5.2. Market Revenue and Forecast, by Technology (2017-2030)

12.5.5.3. Market Revenue and Forecast, by Application (2017-2030)

12.5.5.4. Market Revenue and Forecast, by End user (2017-2030)

12.5.6. Rest of LATAM

12.5.6.1. Market Revenue and Forecast, by Type (2017-2030)

12.5.6.2. Market Revenue and Forecast, by Technology (2017-2030)

12.5.6.3. Market Revenue and Forecast, by Application (2017-2030)

12.5.6.4. Market Revenue and Forecast, by End user (2017-2030)

Chapter 13. Company Profiles

13.1. Rigaku Corporation

13.1.1. Company Overview

13.1.2. Product Offerings

13.1.3. Financial Performance

13.1.4. Recent Initiatives

13.2. Hampton Research Corp

13.2.1. Company Overview

13.2.2. Product Offerings

13.2.3. Financial Performance

13.2.4. Recent Initiatives

13.3. HiMedia Laboratories

13.3.1. Company Overview

13.3.2. Product Offerings

13.3.3. Financial Performance

13.3.4. Recent Initiatives

13.4. Bruker Corporation

13.4.1. Company Overview

13.4.2. Product Offerings

13.4.3. Financial Performance

13.4.4. Recent Initiatives

13.5. Thermo Fisher Scientific, Inc.

13.5.1. Company Overview

13.5.2. Product Offerings

13.5.3. Financial Performance

13.5.4. Recent Initiatives

13.6. Jena Bioscience GmbH

13.6.1. Company Overview

13.6.2. Product Offerings

13.6.3. Financial Performance

13.6.4. Recent Initiatives

13.7. Agilent Technologies

13.7.1. Company Overview

13.7.2. Product Offerings

13.7.3. Financial Performance

13.7.4. Recent Initiatives

13.8. Charles River Laboratories, Inc.

13.8.1. Company Overview

13.8.2. Product Offerings

13.8.3. Financial Performance

13.8.4. Recent Initiatives

13.9. Molecular Dimensions Ltd.

13.9.1. Company Overview

13.9.2. Product Offerings

13.9.3. Financial Performance

13.9.4. Recent Initiatives

13.10. Formulatrix, Inc.

13.10.1. Company Overview

13.10.2. Product Offerings

13.10.3. Financial Performance

13.10.4. Recent Initiatives

Chapter 14. Research Methodology

14.1. Primary Research

14.2. Secondary Research

14.3. Assumptions

Chapter 15. Appendix

15.1. About Us

15.2. Glossary of Terms

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