Protein Engineering Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2030

Published Date : May 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Protein Engineering market size is expected to be worth around US$ 13.9 billion by 2030, according to a new report by Vision Research Reports.

The global Protein Engineering market size was valued at US$ 923.0 million in 2020 and is anticipated to grow at a CAGR of 25.9% during forecast period 2021 to 2030.

Growth Factors

 The market is driven by presence of regulatory authorities consistently striving to reduce time and cost involved in the drug discovery process. One such example is the launch of critical path initiative by U.S. FDA, for incorporation of advanced technologies, such as protein engineering, in drug discovery processes. Moreover, this facilitates prediction of probable adverse reactions & toxicity and improves efficacy of target molecules early on, resulting in lowered drug attrition rates in the later stages. This is anticipated to help control overall expenditure. Rise in R&D expenditure by countries indicates the urgent need for adoption of these tools in all drug discovery and development processes. 

The rising number of government initiatives aimed at enhancing protein engineering capabilities is anticipated to present the market with high growth potential. This has resulted in a significant rise in number of research activities & programs and fund allotment for R&D. For instance, Protein Engineering Network of Centres of Excellence (PENCE) contributed approximately USD 1.0 million for proteomics projects and hosted conferences on proteomics in Canada as an effort to broaden research associated with this technology.

Report Highlights

Rational design dominated the technology segment with a share of over 39.0% in 2020. The dominant share can be attributed to the extensive usage of this technology in antibody and enzyme engineering. The unprecedented expansion in commercial applications and enzyme engineering resulted in enhanced and modified enzymes possessing desired catalytic properties.

Site-directed mutagenesis is one of the frequently used rational design methods that aids in obtaining greater insights on enzyme binding and catalytic mechanisms, which thereby broadens the scope of functional prediction of new genome sequences. The consistent use of rational design has been exemplified in the development of a faster superoxide dismutase, one of the fastest known enzymes in nature.

In addition, it is anticipated that rational design can further be implemented as a consequence of the development of modeling tools and a rapidly growing number of 3Dstructures in databases. Protein remodeling is one of the major applications of rational design, serving as a major contributing factor to the dominant share of rational design.

Hybrid approach is presumed to attain the fastest CAGR of over 16.0% during the forecast period. Hybrid approaches that use a combination of directed evolution and rational design are increasingly used in various applications, such as for enhancement of redox proteins and enzymes. These enzymes hold high importance in the development of nanodevices for biosensing and other major nanotechnology applications, thus engendering future growth prospects.

Instrument accounted for the largest share in the product segment in 2020. The largest share captured by this segment is believed to be a consequence of high preference for automated technology by the researchers in order to facilitate a faster molecule development process. For instance, instrumentation of real-time PCR in quantitation of nucleic acids is highly preferred in academic research, as it facilitates a greater understanding of the chemical structure of mutated nucleic acids

Extensive usage of new technologies and process advancements in proteomic research are high-impact rendering drivers of the market. These technologies include mass spectrometry, gel electrophoresis, and computational prediction programs. These facilitate efficient identification, characterization of proteomes, and determination of function, which are critical aspects of protein engineering, thereby encouraging high adoption of instruments. These factors cumulatively are believed to be responsible for the substantial share in the product segment.

Software & services are expected to witness lucrative CAGR as a consequence of increasing usage in a wide array of applications that suit the interests and needs of researchers. In addition, majority of processes are dependent on software, which is the key factor presumed to be responsible for the high growth potential attained by the segment. The anticipated fast growth is also believed to be a result of complex, multilayered drug development system in which, these services may prove imperative.

The market players are involved in the development of an array of services that simplify the overall process. The services provided by these key players result in reduction of the overall expenditure and, thus, promote the use of these technologies by researchers and scientists.

mAbs accounted for a dominant share of the protein type segment in 2020 and are anticipated to grow at a lucrative rate during the forecast period. Growing R&D expenditure in the development of therapeutically advanced mAbs is presumed to be one of the significant factors responsible for increased adoption of these tools.

High demand for personalized medicine is also considered as a high-impact rendering driver for the growth attained by this segment over the years. Moreover, protein engineering provides various benefits, such as fewer adverse effects and higher homogeneity & specificity of mAbs, which thereby drive the preference by researchers in the modeling of mAbs to yield therapeutically superior versions.

In addition, government initiatives to enable cost-effective production of mAbs are predicted to impel the usage over the coming years. For instance, the National Institute of Standards and Technology in the U.S. has issued biomanufacturing initiative and stringent regulatory guidelines to ensure the effective and safe manufacturing of low-cost, high-quality drugs globally.

The incorporation of technologically advanced genetic platforms that include protein engineering and next-generation sequencing is anticipated to increase the growth potential. In addition, the cost-effective nature of the aforementioned technologies is presumed to support research studies to develop new generation of mAbs, which is anticipated to present a billion-dollar opportunity to major pharmaceutical companies in the future.

Pharmaceutical & biotechnology companies held a dominant share in the end-use segment in 2020. The substantial share can be attributed to the increasing adoption of in silico models to develop new protein-based drugs in the following applications: cancer, diabetes, and central nervous system diseases.

These companies are consistently striving to sustain the market by developing drug variants of a patent expiring drugs by incorporating the computer modeling approach. The increasing inclination of public & private healthcare organizations toward promoting advanced engineering to yield better patient outcomes serves as one of the key factors responsible for the substantial share of the segment.

Furthermore, supportive organizations allot funds to major pharmaceutical and biotechnology companies to develop new- and advanced generation therapeutics, thereby leading to greater adoption of engineering tools by these companies. The aforementioned factors are anticipated to be responsible for the dominant share registered by the segment.

Contract research organizations are expected to grow at a lucrative rate throughout the forecast period. This highest growth can be attributed to the growing inclination of companies to reduce overall expenditure along with utilization of benefits involved. It primarily includes cost advantages, increased efficiency of services, enhanced productivity, and higher focus on the core areas of development-all of which are critical to a company’s growth.

 North America captured a dominant share of the market. A consistent number of collaborations encouraged by key market players for increasing their R&D capabilities are presumed to be responsible for the greater share captured by this region.

Moreover, the established pharmaceutical companies in this region are extensively involved in the commercialization of advanced engineering tools and the promotion of their usage in the research community.

The Asia Pacific market is expected to witness the fastest CAGR during the forecast period owing to the growing presence of contract research organizations, rising healthcare IT spending, and unprecedented evolution of the healthcare infrastructure & standards across this region.

Favorable government initiatives that support research activities and the increasing trend of outsourcing by developed economies also serve as key growth impelling factors for this region. The companies are consistently striving to develop better medication options at a faster and cheaper rate through molecular modeling techniques.

Key Players

Agilent Technologies, Thermo Fisher Scientific, Waters Corporation

Market Segmentation

  • Technology Outlook 

    • Rational Protein Design

    • Directed Evolution

    • Hybrid Approach

  • Product Outlook 

    • Instruments

    • Reagents

    • Software & Services

  • Protein Type Outlook 

    • Insulin

    • Monoclonal Antibodies

    • Vaccines

    • Growth Factors

    • Colony Stimulating Factors

    • Coagulation Factors

    • Interferon

    • Others

  • End-use Outlook 

    • Academic Research Institutes

    • CROs

    • Pharma & Biotech Companies

  • Regional Outlook 

    • North America

      • The U.S.

      • Canada

    • Europe

      • The U.K.

      • Germany

    • Asia Pacific

      • Japan

      • China

      • India

    • Latin America

      • Mexico

      • Brazil

    • Middle East & Africa

      • South Africa

The Protein Engineering market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Protein Engineering market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Protein Engineering market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Protein Engineering market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Protein Engineering market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Protein Engineering capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Protein Engineering by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Protein Engineering market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Protein Engineering market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Protein Engineering market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Protein Engineering industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Protein Engineering market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Protein Engineering market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Protein Engineering market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Protein Engineering market. These factors have benefited the growth of the global market for Protein Engineering. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Protein Engineering. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Protein Engineering are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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