Protein Labeling Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2030

Published Date : Apr 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Protein Labeling market size is expected to be worth around US$ 8.1 billion by 2030, according to a new report by Vision Research Reports.

The global Protein Labeling market size was valued at US$ 2.8 billion in 2020 and is anticipated to grow at a CAGR of 10.2% during forecast period 2021 to 2030.

Growth Factors

The study of Post-translational Modification (PTM) of proteins has gained immense popularity in cell biology and disease treatment and prevention. The introduction of effective quantification methods of protein expression with the use of tagging strategies, such as iodoTMTzero Label Reagent that detects nitrosylation, has driven an efficient determination of PTMs. Therefore, a rise in PTM-related studies is driving the market.

The emergence of novel techniques and the launch of improved products are expected to positively influence market growth. One such development includes the application of new spin labels that expand the capability of site-directed spin labeling of proteins. These labels in combination with electron paramagnetic resonance spectroscopy (SDSL-EPR) enables investigation of protein structure, dynamics, and structural heterogeneity.

Research studies have stated that Host Cell Proteins (HCPs) interfere with biopharmaceutical manufacturing and result in low yields. Thus, it is essential to quantify and eliminate HCPs during such procedures. The advent of two dimensional in blot electrophoresis (2D DIBE) is proven to be an effective technique for HCP detection. It involves the use of a fluorescent dye, such as Cy3, thus creating lucrative opportunities for the demand for new labels in the market.

Report Highlights

Reagents dominated the market for protein labeling with a revenue share of 64.9% in 2019. A rise in the number of labeling agents and genetically engineered labels being discovered is attributed to the estimated share of the reagents segment. Furthermore, the commercial availability of efficient reagents, such as No-Stain Protein Labeling Reagent that enables accurate and reliable protein visualization and normalization, positively impacts the segment growth.

In the reagent segment, the protein segment dominated the market for protein labeling in terms of revenue share. This can be attributive to the usage of monomeric fluorescent proteins that address issues associated with aggregation caused due to electrostatic or hydrophobic interactions in the host and fluorescent protein. Market participants, such as Addgene and Allele Biotechnology, are working in collaboration for the development of such monomeric products.

On the contrary, probes/tags are anticipated to register the fastest growth rate in the forecast period. Different tags are developed to label membrane peptide molecules for super-resolution microscopy. Moreover, the development of peptide-based affinity reagents to achieve higher tag specificities is one of the strategies adopted by various reagent manufacturers, which is expected to result in the development of a larger number of probes or tags in the near future.

The immunological techniques segment dominated the market for protein labeling and accounted for the largest revenue share of 40.3% in 2019. The segment generated maximum revenue of USD 716.5 in 2019. Most of the immunological techniques such as flow cytometry, immunoassays, western blotting, and immunofluorescence, involve the usage of labels. These techniques are majorly used in cancer research as well as autoimmune disease research and the development of therapeutics.

Moreover, these techniques are widely accepted in the detection of diabetes, systemic lupus erythematosus, rheumatoid arthritis, pulmonary diseases, neurological disease, and gastrointestinal diseases. The wide application of immunological techniques contributes to the larger revenue share of the segment. The application of immunoelectron microscopy for defining the position of antigens that are in the resolution of 10 nanometers or finer is also attributive for the estimated revenue share.

The rapid evolution of high-throughput fluorescence microscopy for detailed biological analysis of cellular pathways in academic research has resulted in the fastest growth of the fluorescence microscopy segment during the analysis period. This technique is advantageous over conventional microscopy because it analyzes a large number of samples with high acquisition speed and allows unbiased methods for capturing images.

In terms of revenue, in-vitro methods accounted for the largest revenue share of 69.8% in 2019 and are projected to grow at a lucrative pace in the near future. Among these methods, enzymatic labeling dominated the segment share due to the highly specific action of the enzymes. Covalent site-specific binding of an enzyme aids in the incorporation of bio-orthogonal functionalities into proteins, thereby enabling site-specific protein labeling and engineering.

Nanoparticle-based in-vitro methods are expected to register the fastest CAGR from 2020 to 2027. This method involves the usage of nanoparticles, particularly gold nanoparticles, which can be linked specifically to an antibody or hinge thiol on IgG or Fab. Owing to their small size, nanoparticles are capable of reaching intricate places and form covalent bonds with the target protein or peptide, which provides better labeling and stability.

This method also provides ultra-stability, prevents metal-antibody interactions, and ultra-sensitivity during protein detection and quantification. Classic passive adsorption and covalent conjugation are the most commonly employed strategies during the labeling of peptide molecules by using gold nanoparticles. Moreover, easy conjugation of gold nanoparticles makes it highly popular in R&D and manufacturing procedures of diagnostic kits.

North America dominated the protein labeling market with a share of 46.8% in 2019. The number of research activities employing immunological techniques, fluorescence microscopy, western blotting, ELISA, cell-based assays has increased significantly in this region, which has contributed to the larger revenue share. The high adoption of protein labeling techniques in disease diagnosis-associated studies also fuels the region’s revenue generation.

For instance, a research study published in August 2019, by the researchers from the National Institutes of Health (U.S.), demonstrated the application of a bi-arsenical dye system that permits the fluorescent detection of proteins in different cellular locations. This technology opened new avenues for the investigation of the morphology and motility of Borrelia species and Leptospira species that cause Lyme disease and leptospirosis conditions, respectively.

In Asia Pacific, the market for protein labeling is projected to register a lucrative growth rate during the forecast period. This is due to ongoing research projects that drive the proteomics related research in this region. The Structural Proteomics Project, Proteome Expression Database, Genome Medicine Database Of Japan Proteomics, Chemotherapy and Cancer Proteomics Project, and Structural Genomics are among the few ongoing projects in Japan.

Key Players

  • Thermo Fisher Scientific, Inc.

  • Merck KGaA

  • Perkin Elmer, Inc.

  • Promega Corporation

  • F. Hoffmann-La Roche Ltd.

  • LGC Limited

  • New England Biolabs

  • LI-COR, Inc.

  • GE Healthcare

  • Jena Bioscience GmbH

Market Segmentation

  • Product Outlook

    • Reagents

      • Proteins

      • Enzymes

      • Probes/Tags

      • Monoclonal antibodies

      • Other reagents

    • Kits

    • Services

  • Application Outlook

    • Cell-based Assays

    • Fluorescence Microscopy

    • Immunological Techniques

    • Protein Microarray

    • Mass Spectrometry

  • Method Outlook

    • In-vitro Labeling Methods

      • Enzymatic labeling

      • Dye-based labeling

      • Co-translational labeling

      • Site-specific labeling

      • Nanoparticle labeling

      • Others

    • In-vivo Labeling Methods

      • Photoreactive labeling

      • Radioactive labeling

      • Others

  • Regional Outlook

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • China

      • Japan

    • Latin America

      • Brazil

    • Middle East Africa (MEA)

      • South Africa

The Protein Labeling market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Protein Labeling market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Protein Labeling market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Protein Labeling market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Protein Labeling market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Protein Labeling capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Protein Labeling by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Protein Labeling market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Protein Labeling market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Protein Labeling market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Protein Labeling industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Protein Labeling market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Protein Labeling market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Protein Labeling market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Protein Labeling market. These factors have benefited the growth of the global market for Protein Labeling. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Protein Labeling. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Protein Labeling are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

Featured Research Reports

  • Featured Research Reports

    Clinical Trial Equipment & Ancillary Solutions Market (By Product: Sourcing, Supply/Logistics, Service, Others; By Phase: Phase I, Phase II, Phase III, Phase IV) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

    Read more...
  • Featured Research Reports

    Dental Suction Systems Market (By Product: Wet Suction, Dry Suction; By End-use: Hospitals, Dental Offices) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

    Read more...
  • Featured Research Reports

    Dental Caries Detectors Market (By Product: Laser Fluorescent Caries Detector, Fiber Optic Trans-illumination Caries Detector; By End-use: Hospitals, Dental Clinics, Ambulatory Surgical Centers) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

    Read more...
  • Featured Research Reports

    Ophthalmic Perimeters Market (By Product: Static, Kinetic, Combination; By End-use: Hospital, Ophthalmic Clinic, Others) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

    Read more...
  • Featured Research Reports

    Investigational New Drug CDMO Market (By Product: Small Molecule, Large Molecule; By Service: Contract Development, Contract Manufacturing; By End-use: Pharmaceutical Companies, Biotech Companies, Others (Government, Research Institutes, Academic Institutes, etc.)) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

    Read more...