Scaffold Technology Market (By Type: Hydrogels, Wound Healing, 3D Bioprinting, Immunomodulation; By Application: Stem Cell Therapy, Regenerative Medicine, & Tissue Engineering, Drug Discovery, Others; By Disease Type: Orthopedics, Musculoskeletal, & Spine, Cancer, Skin & Integumentary, Dental, Cardiology & Vascular, Neurology, Urology, GI, Gynecology; By End-use: Biotechnology and Pharmaceutical Industries, Research Laboratories and Institutes, Hospitals and Diagnostic Centers) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

Published Date : Aug 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Scaffold Technology market size is expected to be worth around US$ 12.1 billion by 2030, according to a new report by Vision Research Reports.

The global Scaffold Technology market size was valued at US$ 11.1 billion in 2020 and is anticipated to grow at a CAGR of 18.4% during forecast period 2021 to 2030.

Growth Factors

 The market growth can be primarily attributed to the growing popularity of bioprinting for mimicking the tissue microenvironment in printed 3D tissue models. The need to expand the horizon of multidisciplinary research areas has supplemented the adoption of scaffold technologies in 3D printed models.

For instance, in October 2021, researchers integrated novel biomaterial scaffold-guided regeneration for multiple periodontal tissues. The incorporation of advanced imaging modalities along with 3D printing has facilitated non-invasive tracking of in vivo degradation of scaffolds. Advent of such technologies is expected to propel the adoption of scaffolds in tissue engineering and regeneration, thereby providing considerable momentum to market growth.

Additionally, development of novel diagnostic and therapeutic strategies such as tissue engineering have been largely favored in the wake of the pandemic outbreak of SARS-COV-2 infection. Expanding research activities in the field of tissue engineering have led to the advent of scaffold-based vaccine systems, which have the potential tocombatCOVID-19. Progress in this area is expected to cause a surge in the adoption of advanced medical technologies in COVID-19 vaccine development and research.

Furthermore, researchers are proactively using in vitro human lung tissue models developed using tissue-engineered for the understanding of mechanisms of the infection and host-pathogen interface. The application of tissue engineering is used for culturing multiple pulmonary cell lines, improving the relevance of in vitro models, and the use of 3D scaffolds that mimic native pulmonary architecture.

Report Highlights

The hydrogels emerged as a dominant segment and accounted for the largest revenue share of 42.2% in 2020. Ongoing technological advancements in the microfabrication of hydrogels are expected to boost segment growth in the near future. In addition, companies are launching new hydrogels for cell transplantation, drug depots, and a barrier against restenosis.

For instance, in March 2021, Cultrex UltiMatrix Reduced Growth Factor Basement Membrane Extract (RGF BME)was introduced by Bio-Techne Corporation for culturing pluripotent stem cells and organoids. It is an advanced matrix hydrogelwith optimized extracellular matrix protein composition, increased total protein content, and improved tensile strength for personalized medicine, drug discovery research, and regenerative medicine.

The nanofiber-based scaffolds segment is anticipated to witness a lucrative CAGR of 9.8% over the forecast period. The rising adoption of nanofiber-based scaffolds in tissue engineering and regeneration applications is primarily contributing to the segment growth. In addition, researchers are modifying these scaffolds for expanding their tissue engineering applications.

For instance, based on a January 2020 published research, highlighted that modified nanofibrous scaffolds represented a potential platform for bone tissue engineering. The enhanced nanofibrous scaffolds are modified using wet chemistry (covalent) or mineralization that can efficiently mimic native bone tissue. In addition, the study also concluded that these scaffolds can also be used for the sustained release of growth factors.

The stem cell therapy, regenerative medicine, and tissue engineering segment dominated the market for scaffold technology and accounted for the largest revenue share of more than 66.0% in 2020.The growth is attributed to the growing implementation of scaffold technology for reconstruction surgeries, aesthetic surgeries, soft tissue tumor repair, abdominal wall repair, periodontology, and colorectal surgeries.

In addition, the extensive application of scaffold technology across the field of regenerative medicine is gaining significant traction among researchers in recent years. For instance, in November 2020, scientists from Wake Forest Institute for Regenerative Medicine scientists (WFIRM) developed a hybrid tissue construct that can be used for cartilage regeneration. It is developed with the application of 3D bioprinting technology. Hence, the growing research for the development of tissue can be further attributed to segment growth.

The drug discovery segment is expected to witness substantial growth during the forecast period. The need to develop robust and portable tools in the field of biomedical science, including drug discovery and therapeutic development, has driven the demand for scaffold technology in this segment. The technology facilitates the efficient elucidation of molecular reasons for the activity of drug candidates in toxicity screening procedures as compared to conventional procedures.

The orthopedics, musculoskeletal, and spine segment dominated the market for scaffold technology and accounted for the largest revenue share of more than 50.0% in 2020. It is estimated that nearly 34.0 million surgeries on the musculoskeletal system are performed in the United States annually. Hence, regenerative medicines are gaining momentum as they offer various lower-risk substitutes to allograft surgery.

The neurology segment is expected to witness the fastest CAGR from 2021 to 2030 due to the high adoption of stem cell therapy and regenerative medicine for the treatment of neurodegenerative disorders. In addition, researchers are developing new scaffolds for nerve regeneration, which is further contributing to segment growth.

For instance, in January 2021, researchers developed a bioactive scaffold based on immobilized nerve growth factor (NGF) containing polycaprolactone/chitosan (PCL/CS) nanofibers for supporting nerve regeneration. This scaffold facilitated increased cell attachment and nerve cell growth.

The biotechnology and pharmaceutical industries segment dominated the market for scaffold technology and accounted for the largest revenue share of46.7% in 2020. The growth in the segment is due to the extensive application of scaffold technology by these industries in tissue engineering fields including periodontal regeneration, cartilage development, bone formation, repair of nasal and auricular malformations, tendon repair, and heart valves.

biotechnology companies are also collaborating for the development of new synthetic scaffolds. For instance, in November 2020, the U.K. biotechnology companies including Manchester BIOGEL and Cellesce developed three-dimensional (3D) scaffolds that can accurately mimic the physiological environment, enabling the manufacturing and scale-up of patient-derived organoids. Hence, such funded initiatives for biotech companies for developing new scaffolds further boost the segment growth.

The hospitals and diagnostic centers segment is expected to witness a lucrative CAGR of 8.8% over the forecast period. The growth in the segment is owing to an increase in the number of grafting procedures and an increase in cases of road accidents and related injuries, all of which create a greater demand for biological scaffolds.

North America dominated the scaffold technology market and accounted for the largest revenue share of 40.6% in 2020 and is expected to continue its dominance during the forecast period. The growth in this region is driven by the presence of prominent players such as Thermo Fisher Scientific Inc.; Akron Biotech; 3D Biotek LLC; Molecular Matrix Inc.; Xanofi; and Corning Incorporated.

In addition, companies in this region are launching new and innovative products for supporting the development of 3D cell culture, which can be further attributed to the region’s growth. For instance, in December 2020, eNuvio a Canada-based company launched a reusable 3D cell culture microplate. The unique geometry of the microplate helped in the generation of high reproducibility and enabledhigh-quality optical observation.

In AsiaPacific, the market for scaffold technology is expected to witness lucrative growth over the forecast period. The growth in the region can be attributed to the presence of government organizations that conducts regenerative medicine and stem cell research. For instance, in India, the Ministry of Science and Technology and the Indian Council of Medical Research focus on stem cell research and regenerative medicine. Furthermore, the researches undertaken by National Centre for Cell Science in stem cell biology and other advanced therapy areas is expected to increase penetration of scaffold technology in the country.

Key Players

  • Thermo Fisher Scientific, Inc.

  • Merck KGaA

  • Tecan Trading AG

  • REPROCELL Inc.

  • 3D Biotek LLC

  • Becton, Dickinson and Company

  • Medtronic

  • Xanofi

  • Molecular Matrix, Inc.

  • Matricel GmbH

  • Pelobiotech

  • 4titude

  • Corning Incorporated

  • Akron Biotech

  • Bioquote Ltd

  • Avacta Life Sciences Limited.

  • Nanofiber Solutions

  • Vericel Corporation

  • NuVasive, Inc.

  • Allergan

Market Segmentation

  • Type Outlook 

    • Hydrogels

      • Polymeric Scaffolds

      • Micropatterned Surface Microplates

      • Nanofiber Based Scaffolds 

    • Wound Healing

    • 3D Bioprinting

    • Immunomodulation

  • Application Outlook 

    • Stem Cell Therapy, Regenerative Medicine, & Tissue Engineering

    • Drug Discovery

    • Others

  • Disease Type Outlook 

    • Orthopedics, Musculoskeletal, & Spine

    • Cancer

    • Skin & Integumentary

    • Dental

    • Cardiology & Vascular

    • Neurology

    • Urology

    • GI, Gynecology

    • Others

  • End-use Outlook

    • Biotechnology and Pharmaceutical Industries

    • Research Laboratories and Institutes

    • Hospitals and Diagnostic Centers

    • Others

  • Regional Outlook 

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • China

      • Japan

    • Latin America

      • Brazil

    • Middle East & Africa

      • South Africa

The Scaffold Technology market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Scaffold Technology market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Scaffold Technology market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Scaffold Technology market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Scaffold Technology market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Scaffold Technology capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Scaffold Technology by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Scaffold Technology market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Scaffold Technology market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Scaffold Technology market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Scaffold Technology industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Scaffold Technology market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Scaffold Technology market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Scaffold Technology market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Scaffold Technology market. These factors have benefited the growth of the global market for Scaffold Technology. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Scaffold Technology. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Scaffold Technology are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market

To strategically profile the key players and comprehensively analyze their growth strategies.


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