Short-read Sequencing Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2028

Published Date : Jan 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Short-read Sequencing market size is expected to be worth around US$ 18.70 billion by 2028, according to a new report by Vision Research Reports.

The global Short-read Sequencing market size was valued at US$ 8.86 billion in 2020 and is anticipated to grow at a CAGR of 11.40% during forecast period 2021 to 2028.

Growth Factors

Rising demand for personalized medicine and companion diagnostics is anticipated to drive the growth.

In addition, initiatives taken by key players to enhance their market presence are expected to boost revenue generation in the market for short-read sequencing. For instance, in March 2019, Illumina partnered with Boai NKY Medical Holdings, a China-based producer of polyvinylpyrrolidone, to develop NGS-based systems for in-vitro diagnosis of hereditary diseases. The novel systems would be developed by using NKY's library prep kits and analysis software and Illumina’s MiniSeq system.

Other major market players have also entered into partnerships and collaborations for expansion in the Asian market as Asia Pacific offers a wide customer-base of patients suffering from chronic disorders that can be diagnosed easily using sequencing methods.

Major application areas of short-read sequencing include reproductive screening, oncology, noninvasive prenatal testing, infectious disease, and pharmacogenomics. A rise in adoption of sequencing platforms for diagnosis of the aforementioned clinical conditions is expected to have a positive impact on the overall market growth.

Report Highlights

 next generation accounted for the largest revenue share of the short-read sequencing market in 2020, as this technology serves as a rapid and cost-effective method for the detection of genetic abnormalities. Moreover, the high throughput nature of NGS to sequence millions of genome fragments simultaneously in each run is projected to drive the adoption of NGS-based protocols.

On the other hand, Sanger sequencing method is ideal for the analysis of a single nucleotide fragment at a time. Therefore, it is a cost-effective and fast method when the number of targets is low (usually 1 to 20). However, low sensitivity and scalability of Sanger methods compared to NGS impedes the segment growth.

The consumables are to be procured at regular intervals by end users to carry out genome analysis as a consequence of higher consumption in multiple sequence runs. This has resulted in the substantial share of the segment in 2020. Instruments like genetic analyzers are used to sequence DNA or its fragments for a wide range of applications such as, Sanger sequencing, methylation, mutation analyses, and STR and SNP profiling. The advent of automated instruments has enhanced the efficiency of several genome analysis platforms available in the market.

The services segment is expected to register the fastest CAGR during the forecast period. Key players, such as Illumina and Roche offer a wide range of NGS-based short-read sequencing services at special prices to the academic researchers, thereby boosting the research in this sector.

The oncology segment accounted for a major market share in 2020 and is expected to maintain its dominance throughout the forecast period. Advanced platforms have enhanced the efficacy of sequencing of cancer genes from multiple genome sets. This allows medical specialists to understand the genetic makeup of tumor cells and advice therapeutics accordingly.

Companies such as Foundation Medicine provide actionable pan-cancer panels for NGS-based targeted sequencing that enable physicians to personalize treatment and select the most appropriate therapy based on the tumor genotype, while also enabling targeted drug development. Similarly, Myriad Genetics offers genetic testing through its myRisk product to identify people who may be at a higher risk of developing certain cancers.

Sequencing accounted for the largest revenue share of the market for short-read sequencing in 2020 as it the most important phase of the complete workflow. The penetration of the market participants in this step of the workflow adds to the revenue generated from this step.

High competition in the market has led to the launch of the novel and portable platforms that can be easily used to sequence DNA. These platforms include MiSeq, iSeq, MiniSeq, and NovaSeq, series from Illumina and IonS5, Ion Proton, and PGM from Thermo Fisher Scientific. These companies engage in research endeavors to reduce the impact of challenges associated with the application of short read protocols.

Academic research held the largest market share in 2020. Rise in research projects across the academic institutes owing to the availability of data analysis platforms at special licensing prices to the universities is expected to drive the growth. The presence of several research grants to these institutes contributes to the larger revenue generation from these end-users.

Higher usage of sequencing methodologies in research, academic workshops, and on-site  courses offered by universities is further expected to enhance the share of the academic research segment. On the other hand, the demand for advanced technologies for clinical diagnostics is regarded as a high impact rendering driver for the growth of the clinical research segment.

North America led the market for short-read sequencing with a share of 40.0%, with Europe following closely. Availability of a regulatory environment supporting the development of genomics is the key factor contributing to the estimated revenue share. In addition, presence of the key players, such as Illumina and Roche with a well-established distribution network across the region further strengthens the regional market growth.

Key Players

Thermo Fisher Scientific Inc.; Hoffmann-La Roche AG; Qiagen N.V.; Illumina, Inc.; Genewiz; Genscript Biotech Corporation; 10x Genomics; Macrogen, Inc.; Agilent Technologies; BGI Genomics; Fasteris SA; and GE healthcare

Market Segmentation

  • Technology Outlook 

    • Next-Generation Sequencing

    • Sanger Sequencing

  • Product Outlook 

    • Instruments

    • Consumables

    • Services

  • Application Outlook

    • Oncology

    • Clinical Investigation

    • Reproductive Health

    • HLA Typing/Immune System Monitoring

    • Metagenomics, Epidemiology & Drug Development

    • Agrigenomics & Forensics

    • Consumer Genomics

  • Workflow Outlook

    • Pre-Sequencing

    • Sequencing

    • Data Analysis

  • End Use Outlook 

    • Academic Research

    • Clinical Research

    • Hospitals & Clinics

    • Pharma & Biotech Entities

    • Other

  • Regional Outlook 

    • North America

      • The U.S.

      • Canada

    • Europe

      • Germany

      • The U.K.

    • Asia Pacific

      • Japan

      • China

    • Latin America

      • Brazil

    • MEA

      • South Africa

The Short-read Sequencing market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Short-read Sequencing market for the base year 2020 and the forecast between 2021 and 2028. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Short-read Sequencing market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Short-read Sequencing market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Short-read Sequencing market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Short-read Sequencing capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Short-read Sequencing by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Short-read Sequencing market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2028. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Short-read Sequencing market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Short-read Sequencing market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Short-read Sequencing industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Short-read Sequencing market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Short-read Sequencing market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Short-read Sequencing market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Short-read Sequencing market. These factors have benefited the growth of the global market for Short-read Sequencing. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Short-read Sequencing. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Short-read Sequencing are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2020
  • Forecast Year 2021 to 2028

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2028);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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