The global Skeletal Dysplasia market size is expected to be worth around US$ 3.10 billion by 2028, according to a new report by Vision Research Reports.
The global Skeletal Dysplasia market size was valued at US$ 2.10 billion in 2020 and is anticipated to grow at a CAGR of 4.06% during forecast period 2021 to 2028.
Increasing prevalence of this condition, especially in children, and growing adoption of orphan drugs are likely to contribute to the expansion of the market.
Among different disorders, achondroplasia is the most common condition. According to estimates published by the National Human Genome Research Institute in 2016, achondroplasia occurs in 1 in 15,000-40,000 live births. Although there are no current therapies approved specifically for achondroplasia, there are five therapies under clinical development.
Genetic defects attributable to the disorder include spontaneous mutations in the FGFR3 gene. Vosoritide by BioMarin targets inhibition of the FGFR3 pathway and presents a first-in-class drug for achondroplasia. The drug is in phase III clinical trial and is expected to enter the market in 2024. Clementia (Ipsen Group) and Regeneron are other market players targeting disorders such as multiple osteochondromas and fibrodysplasia ossificans progressiva (FOP). Approval of these pipeline therapies with orphan drug status during the forecast period will further support skeletal dysplasia market growth.
Based on type, the market is segmented into X-linked hypophosphatemia (XLH), hypophosphatasia (HPP), achondroplasia, fibrodysplasia ossificans progressive (FOP), and multiple osteochondromas (MO). HPP dominated the market in 2020 owing to increasing prevalence of the disease. According to an article published by the Orphanet in 2015, the prevalence of HPP is estimated to be 1 per 300,000 births in Europe.
FOP is estimated to expand at a lucrative CAGR of 12.7% over the forecast period. Strong presence of pipeline products and increasing awareness of the disease are some factors responsible for segment growth over the forecast years. For instance, the International Fibrodysplasia Ossificans Progressive Association (IFOPA), a nonprofit organization providing support to individuals with FOP, educates patients and their families about the disease and its management. Furthermore, IFOPA supports various researches by providing funds to raise awareness of the disease and find a cure.
Based on treatment, the skeletal dysplasia market is categorized into medication and surgery. Surgery held the largest market share in 2018 as it is the most effective available treatment option for types such as achondroplasia and HPP. Increasing preference of patients toward surgeries is anticipated to be one of the major factors responsible for segment growth. The medication segment is estimated to witness the fastest growth over the forecast period owing to rising initiatives focusing on developing novel drugs for the treatment of certain types of skeletal dysplasia such as FOP and MO.
Europe dominated the global market for skeletal dysplasia with a share of 46.8% in 2020. High adoption of surgeries for treatment and rising awareness of the disease are some of the major factors responsible for the region’s dominance. For instance, the European Skeletal Dysplasia Network (ESDD), a nonprofit organization, provides an integrated diagnostic and research network for skeletal dysplasia.
North America is estimated to be the fastest growing region by 2026 owing to increasing prevalence of the disease and rising R&D initiatives for the development of effective drugs. For instance, according to an article published by the American Dental Association in 2018, XLH affects approximately 12,000 adults and 3,000 children in the U.S. The Asia Pacific market accounts for a smaller share owing to a relatively lower prevalence of rare disorders like skeletal dysplasia. However, technological advancements, boost of medical tourism, and collaborations with national and international organizations in the field will prove to be lucrative for this regional market.
BioMarin; Amgen Inc.; Merck KGaA; Regeneron; Alexion Pharmaceuticals, Inc.; and Clementia (Ipsen Group).
Fibrodysplasia ossificans progressive
Middle East & Africa
The Skeletal Dysplasia market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.
The report provides size (in terms of volume and value) of Skeletal Dysplasia market for the base year 2020 and the forecast between 2021 and 2028. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.
This report focuses on the global Skeletal Dysplasia market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Skeletal Dysplasia market development in United States, Europe and China.
It is pertinent to consider that in a volatile global economy, we haven’t just conducted Skeletal Dysplasia market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.
In terms of production side, this report researches the Skeletal Dysplasia capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.
In terms of consumption side, this report focuses on the consumption of Skeletal Dysplasia by regions (countries) and application.
Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Skeletal Dysplasia market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2028. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.
With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Skeletal Dysplasia market companies.
Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Skeletal Dysplasia market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.
The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.
Overall, this is an in-depth research report specifically for the Skeletal Dysplasia industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.
The Skeletal Dysplasia market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Skeletal Dysplasia market.
Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Skeletal Dysplasia market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.
Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Skeletal Dysplasia market. These factors have benefited the growth of the global market for Skeletal Dysplasia. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.
New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Skeletal Dysplasia. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).
In this study, the years considered to estimate the market size of Skeletal Dysplasia are as follows:
Reasons to Purchase this Report:
- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.
This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.
Market Size Estimation
Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).
The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.
Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.
All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.
Market Breakdown and Data Triangulation
After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.
Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.
In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.
The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.
The study objectives of this report are:
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