Small-scale Bioreactors Market (By Capacity; By Product: Reusable, Single-use; By End-user: CROs & CMOs, Pharma & Biopharma Companies) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook and Forecast 2023-2032

The global small-scale bioreactors market was surpassed at USD 1.69 billion in 2022 and is expected to hit around USD 6.72 billion by 2032, growing at a CAGR of 14.8% from 2023 to 2032.

Small-scale Bioreactors Market Size 2023 to 2032

Key Pointers

  • The 1L-3L capacity segment dominated the global industry in 2022 and accounted for the maximum share of more than 31.03% of the overall revenue. The segment is projected to expand further at the fastest growth rate retaining its dominant position throughout the forecast period. This is due to the wide-scale availability of bioreactors with a working volume capacity of 1L-3L. Due to the advantages of these systems in laboratories, the majority of key players also offer these products.
  • The 3L-5L capacity segment is estimated to register the second-fastest growth rate during the forecast period. Products with 3-5L capacity offer numerous benefits for R&D fermentation process development, including quick system implementation, increased size & turnaround flexibility, reduced infrastructure, decreased risk of cross-contamination, and minimal maintenance requirement.
  • The CROs & CMOs segment accounted for the largest revenue share of 45.81% in 2022. The segment is projected to expand further at the fastest CAGR retaining its dominant position throughout the forecast period. 
  • The academic & research institutes segment is also estimated to have significant growth during the forecast period since the small-scale bioreactors are adopted for different procedures at a higher rate in academic and research institutes.
  • The reusable bioreactors segment dominated the industry in 2022 and accounted for the largest share of more than 80.07% of the overall revenue as there is a higher need for reusable bioreactors in the pharmaceutical and biopharmaceutical industries due to the fact that reusable bioreactors can produce larger quantities of products.
  • The single-use bioreactors product segment is expected to register the fastest growth rate during the forecast period as these single-use bioreactors have recently been used more frequently in novel biotech processes. This is mainly due to their exceptional ability to improve flexibility, lower investment, and reduce operational expenses. Such advantages of single-use products over other small-scale bioreactors are expected to drive segment growth.
  • North America dominated the market in 2022 with a share of 43.64%. The rising investments in biopharmaceutical research, owing to the growing incidences of chronic disease & increased demand for novel biologic drugs as well as advanced equipment including small-scale bioreactors, will drive the industry growth. 
  • Asia Pacific is expected to register the fastest CAGR during the forecast period due to it being the home to some of the world’s most rapidly expanding biotechnological industries and economies.

Report Scope of the Small-scale Bioreactors Market

Report Coverage Details
Market Size in 2022 USD 1.69 billion
Revenue Forecast by 2032 USD 6.72 billion
Growth rate from 2023 to 2032 CAGR of 14.8%
Base Year 2022
Forecast Period 2023 to 2032
Market Analysis (Terms Used) Value (US$ Million/Billion) or (Volume/Units)
Regions Covered North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Companies Covered Sartorius AG; Thermo Fisher Scientific Inc.; Merck KGaA; Danaher Corp.; Lonza Group; Eppendorf AG; Miltenyi Biotec; Getinge AB; Solaris Biotechnology Srl; Infors AG


The key drivers responsible for the market growth include the wide-scale product usage in the pharmaceutical industry along with portfolio expansion by major players. Small-scale bioreactors are essential for the development and optimization of processes, therefore they are frequently used in pharmaceutical and biopharmaceutical research. These bioprocessing equipment are generally used for small-scale production and range in size from a few milliliters to 5-10 L. The COVID-19 pandemic has witnessed an increased demand as a result of the sudden rise in COVID-19 cases.

The sales of small-scale bioreactors significantly increased in 2020 and 2021 as a result of numerous businesses expanding their facilities to carry out R&D for COVID-19 vaccines. Moreover, the worldwide immunization campaigns around the globe and the rising demand are expected to increase product sales during the forecast period. In addition, heavy investments by government authorities to improve biopharmaceutical research and the development of a vaccine are also influencing the industry’s growth. For instance, the South Korean government allocated USD 250 million in April 2020 to launch the Vaccine Innovative Technology Alliance (VITAL), which will help with vaccine research, production, and use. To make South Korea the fifth-largest vaccine manufacturer throughout the globe by 2025 and reach 80% vaccine self-sufficiency, the nation has spent an additional $2 billion on the K Vaccine program.

Moreover, the rising prevalence of chronic diseases, such as cancer, cardiac disease, diabetes, and hypertension, has led to more focus on the development of innovative biological therapies. Similarly, the demand for monoclonal antibodies as well as personalized medicines has increased bioproduction, accelerating small-scale bioreactor demand. Furthermore, the rising usage of high-end technologies to simplify complex manufacturing will enhance the demand for small-scale bioreactors during the forecast period. In addition, the high investments in research and development activities by key biopharmaceutical companies are expected to drive industry growth. For instance, in august 2021, PBS Biotech, a manufacturer of single-use bioprocessing devices, completed a USD 10 million private financing round with BroadOak Capital Partners.

With the funds, the company will have the opportunity to grow and commercialize its line of single-use bioreactor devices and outsourced process design services. Due to the demand for superior quality and better efficiency in drug manufacturing, the biopharmaceutical industry is quickly shifting toward the use of single-use bioprocessing systems with integrated real-time monitoring and technical analysis that can facilitate automation, enhance data-driven quality control, and continue driving performance. Therefore, it is expected that the shift toward advanced bioprocessing technology devices, such as small-scale bioreactors, will propel the growth of this market.

Small-scale Bioreactors Market Segmentations:

By Product

  • Reusable Bioreactors
    • Stainless Steel Bioreactors
    • Glass Bioreactors
  • Single-use Bioreactors

By Capacity

  • 5 ML -100 ML
  • 100 ML-250 ML
  • 250 ML -500 ML
  • 500 ML-1 L
  • 1L-3L
  • 3L-5L

By End-user

  • Pharmaceutical & Biopharmaceutical Companies
  • CROs & CMOs
  • Academic & Research Institutes

Frequently Asked Questions

The global small-scale bioreactors market size was reached at USD 1.69 billion in 2022 and it is projected to hit around USD 6.72 billion by 2032.

The global small-scale bioreactors market is growing at a compound annual growth rate (CAGR) of 14.8% from 2023 to 2032.

The North America region has accounted for the largest small-scale bioreactors market share in 2022.

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