The Europe gene synthesis (research use) market was valued at USD 0.35 billion in 2022 and it is predicted to surpass around USD 1.52 billion by 2032 with a CAGR of 15.85% from 2023 to 2032.
Key Pointers
Report Scope of the Europe Gene Synthesis (Research Use) Market
Report Coverage | Details |
Market Size in 2022 | USD 0.35 billion |
Revenue Forecast by 2032 | USD 1.52 billion |
Growth rate from 2023 to 2032 | CAGR of 15.85% |
Base Year | 2022 |
Forecast Period | 2023 to 2032 |
Market Analysis (Terms Used) | Value (US$ Million/Billion) or (Volume/Units) |
Companies Covered | GenScript; Azenta, Inc. (GENEWIZ); Boster Biological Technology; Twist Bioscience; ProteoGenix, Inc; Biomatik; ProMab; Thermo Fisher Scientific, Inc.; Integrated DNA Technologies, Inc. (Danaher); OriGene Technologies, Inc |
The increasing applications of the technique in synthetic biology & genomic engineering along with technological advancements in gene synthesis methods are driving the expansion of this market. The rising adoption of gene synthesis in designing personalized medicines is projected to fuel the expansion of the regional market over the forecast period.
The COVID-19 pandemic severely impacted the gene synthesis (research use) market. Despite the economic recession due to the pandemic, the synthetic biology & gene synthesis markets have witnessed a significant increase in investments. Moreover, the market was impacted due to various research initiatives introduced based on DNA synthesis for developing treatments and vaccines for COVID-19. For instance, a study was published by the University of Oxford in which researchers evaluated the efficacy of existing synthetic plasmid DNA-based vaccines. The researchers also developed a synthetic DNA vaccine for the SARS-CoV2 virus.
The rising investments in the synthetic biology market are expected to propel the market growth over the forecast period. Due to the growing demand, investors have recently shifted their focus toward the synthesis biology industry. For instance, in 2020, eureKARE company was formed to focus on development and financing activities related to innovation in synthetic biology across Europe. Moreover, in May 2021, the company raised USD 60 million to develop microbiome and synthetic biology startups.
In addition, approximately USD 7.8 billion was invested in the synthetic biology field through public and private financing in 2020. This amount is nearly 2.5 times the funding received in 2019. The increased availability of public financing, along with the role of exchange-traded funds, has driven investments in this market. These increasing investments and funding activities can strengthen the growth over the coming years.
Over the projected period, the regional market’s growth is expected to be driven by technological advancements in DNA synthesis platforms. The launch of innovative DNA synthesis platforms with technologically cutting-edge specifications that address the increased demand of researchers is expected to support market growth. For instance, DNA Script launched the SYNTAX System in June 2021, the first benchtop nucleic acid printer based on EDS technology in the industry. The SYNTAX System is an integrated, automated printer that produces 96 DNA oligos simultaneously, each with a length of up to 60 nucleotides.
It produces it ready for use in molecular biology and genomics operations without extra processing. By enabling quick, on-site synthesis of DNA oligos for use in genomics processes such as qPCR, amplicon sequencing, endpoint PCR, and mutagenesis, DNA Script aims to speed up the development cycle for assay improvement. Such technological advancements in DNA synthesis systems can reduce the processing time and cost of DNA synthesis and sequencing, providing numerous synthesizing platforms.
Method Insights
Based on method, the market is segmented into solid-phase, chip-based, and PCR-based enzyme synthesis. Solid-phase synthesis segment dominated the market in 2022 with a share of 39% due to the presence and widespread use of this technique, along with the increasing automation in solid-phase technology, which enhanced the efficiency of DNA synthesis. A rise in the adoption of solid-phase synthesis for biophysical studies also favors segment demand.
The PCR-based enzyme synthesis method is expected to witness the fastest CAGR of 17.93% over the forecast period. The growth of the segment can be attributed to the restraints of the chemical synthesis process, such as producing desired quality DNA for only up to a limited length and the environmental impact of the harsh chemicals used.
Services Insights
In the services segment, the antibody DNA synthesis segment held the largest market share of 62% in 2022, owing to an increase in the adoption of gene synthesis in the production of antibodies used for research and the availability of cutting-edge recombinant technology. Furthermore, the increased importance of personalized antibodies and related research for cancer or genetic disorders drives the segment.
The viral DNA synthesis segment is expected to grow at the fastest CAGR of 18.64% during 2023-2032. Gene synthesis enables the construction of viral DNA in the laboratory without needing an existent virus sample. Moreover, the synthesis of viral genomes also assists in recognizing the gene functions and pathogenicity of the organism, allowing for the development of better treatment or disorder prevention options. These applications of viral DNA synthesis services are anticipated to drive the segment.
Application Insights
Based on application, the gene synthesis market is segmented into gene & cell therapy development, vaccine development, and others. The gene & cell therapy development segment held a revenue share of 55% in 2022, and it is anticipated to showcase the fastest CAGR over the forecast period. The dominance and growth of the segment can be attributed to several factors, including increasing gene & cell therapy approvals and the growing use of gene synthesis methods for cloning synthetic therapeutic genes in viral vectors. Moreover, the growing adoption of gene & cell therapies and increasing government support are anticipated to drive the segment in the coming years.
Research Phase Insights
Based on research phase, the Europe gene synthesis (research use) market is segmented into preclinical and clinical. The clinical segment accounted for the largest regional market share of 73% in 2022. The segment is also projected to display lucrative growth over the forecast period with a CACR of 17.25%. The segment's growth is expected to be driven by the increase in the number of clinical trials for advanced therapy medicinal products. In addition, biomarker discovery and disease modeling are also anticipated to propel segment growth by 2032.
End-use Insights
Based on end-use, the gene synthesis market is segmented into academic & government research institutes, biotechnology & pharmaceutical companies, and contract research organizations (CROs). The academic & government research institutions segment dominated the market with a revenue share of 43% in 2022. The segment's dominance is due to expanding research prospects aimed at exploring the use of gene synthesis for studying model organisms. Moreover, enhanced flexibility and automation in gene synthesis facilitated a growing penetration of the technique in research laboratories. Collaborations between industry and academia are expected to boost segment growth over the coming years.
The contract research organization end-use segment is expected to witness the fastest CAGR of 18.24% throughout the forecast period. The growing number of small biotechnology companies and increasing outsourcing trends are anticipated to impact segment growth in the forthcoming years.
Europe Gene Synthesis (Research Use) Market Segmentations:
By Method
By Service
By Application
By Research Phase
By End-use
Chapter 1. Introduction
1.1. Research Objective
1.2. Scope of the Study
1.3. Definition
Chapter 2. Research Methodology
2.1. Research Approach
2.2. Data Sources
2.3. Assumptions & Limitations
Chapter 3. Executive Summary
3.1. Market Snapshot
Chapter 4. Market Variables and Scope
4.1. Introduction
4.2. Market Classification and Scope
4.3. Industry Value Chain Analysis
4.3.1. Raw Material Procurement Analysis
4.3.2. Sales and Distribution Channel Analysis
4.3.3. Downstream Buyer Analysis
Chapter 5. COVID 19 Impact on Europe Gene Synthesis (Research Use) Market
5.1. COVID-19 Landscape: Europe Gene Synthesis (Research Use) Industry Impact
5.2. COVID 19 - Impact Assessment for the Industry
5.3. COVID 19 Impact: Major Government Policy
5.4. Market Trends and Opportunities in the COVID-19 Landscape
Chapter 6. Market Dynamics Analysis and Trends
6.1. Market Dynamics
6.1.1. Market Drivers
6.1.2. Market Restraints
6.1.3. Market Opportunities
6.2. Porter’s Five Forces Analysis
6.2.1. Bargaining power of suppliers
6.2.2. Bargaining power of buyers
6.2.3. Threat of substitute
6.2.4. Threat of new entrants
6.2.5. Degree of competition
Chapter 7. Competitive Landscape
7.1.1. Company Market Share/Positioning Analysis
7.1.2. Key Strategies Adopted by Players
7.1.3. Vendor Landscape
7.1.3.1. List of Suppliers
7.1.3.2. List of Buyers
Chapter 8. Europe Gene Synthesis (Research Use) Market, By Method
8.1. Europe Gene Synthesis (Research Use) Market, by Method, 2023-2032
8.1.1. Solid-phase Synthesis
8.1.1.1. Market Revenue and Forecast (2020-2032)
8.1.2. Chip-based Synthesis
8.1.2.1. Market Revenue and Forecast (2020-2032)
8.1.3. PCR-based Enzyme Synthesis
8.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 9. Europe Gene Synthesis (Research Use) Market, By Service
9.1. Europe Gene Synthesis (Research Use) Market, by Service, 2023-2032
9.1.1. Antibody DNA Synthesis
9.1.1.1. Market Revenue and Forecast (2020-2032)
9.1.2. Viral DNA Synthesis
9.1.2.1. Market Revenue and Forecast (2020-2032)
9.1.3. Others
9.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 10. Europe Gene Synthesis (Research Use) Market, By Application
10.1. Europe Gene Synthesis (Research Use) Market, by Application, 2023-2032
10.1.1. Gene & Cell Therapy Development
10.1.1.1. Market Revenue and Forecast (2020-2032)
10.1.2. Vaccine Development
10.1.2.1. Market Revenue and Forecast (2020-2032)
10.1.3. Others
10.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 11. Europe Gene Synthesis (Research Use) Market, By Research Phase
11.1. Europe Gene Synthesis (Research Use) Market, by Research Phase, 2023-2032
11.1.1. Pre-clinical
11.1.1.1. Market Revenue and Forecast (2020-2032)
11.1.2. Clinical
11.1.2.1. Market Revenue and Forecast (2020-2032)
Chapter 12. Europe Gene Synthesis (Research Use) Market, By End-use
12.1. Europe Gene Synthesis (Research Use) Market, by End-use, 2023-2032
12.1.1. Biotechnology and Pharmaceutical Companies
12.1.1.1. Market Revenue and Forecast (2020-2032)
12.1.2. Academic and Government Research Institutes
12.1.2.1. Market Revenue and Forecast (2020-2032)
12.1.3. Contract Research Organizations
12.1.3.1. Market Revenue and Forecast (2020-2032)
Chapter 13. Europe Gene Synthesis (Research Use) Market, Regional Estimates and Trend Forecast
13.1. Europe
13.1.1. Market Revenue and Forecast, by Method (2020-2032)
13.1.2. Market Revenue and Forecast, by Service (2020-2032)
13.1.3. Market Revenue and Forecast, by Application (2020-2032)
13.1.4. Market Revenue and Forecast, by Research Phase (2020-2032)
13.1.5. Market Revenue and Forecast, by End-use (2020-2032)
Chapter 14. Company Profiles
14.1. GenScript
14.1.1. Company Overview
14.1.2. Product Offerings
14.1.3. Financial Performance
14.1.4. Recent Initiatives
14.2. Azenta, Inc. (GENEWIZ)
14.2.1. Company Overview
14.2.2. Product Offerings
14.2.3. Financial Performance
14.2.4. Recent Initiatives
14.3. Boster Biological Technology
14.3.1. Company Overview
14.3.2. Product Offerings
14.3.3. Financial Performance
14.3.4. Recent Initiatives
14.4. Twist Bioscience
14.4.1. Company Overview
14.4.2. Product Offerings
14.4.3. Financial Performance
14.4.4. Recent Initiatives
14.5. ProteoGenix, Inc
14.5.1. Company Overview
14.5.2. Product Offerings
14.5.3. Financial Performance
14.5.4. Recent Initiatives
14.6. Biomatik
14.6.1. Company Overview
14.6.2. Product Offerings
14.6.3. Financial Performance
14.6.4. Recent Initiatives
14.7. ProMab
14.7.1. Company Overview
14.7.2. Product Offerings
14.7.3. Financial Performance
14.7.4. Recent Initiatives
14.8. Thermo Fisher Scientific, Inc.
14.8.1. Company Overview
14.8.2. Product Offerings
14.8.3. Financial Performance
14.8.4. Recent Initiatives
14.9. Integrated DNA Technologies, Inc. (Danaher)
14.9.1. Company Overview
14.9.2. Product Offerings
14.9.3. Financial Performance
14.9.4. Recent Initiatives
14.10. OriGene Technologies, Inc
14.10.1. Company Overview
14.10.2. Product Offerings
14.10.3. Financial Performance
14.10.4. Recent Initiatives
Chapter 15. Research Methodology
15.1. Primary Research
15.2. Secondary Research
15.3. Assumptions
Chapter 16. Appendix
16.1. About Us
16.2. Glossary of Terms