Primary Cell Culture Market (By Product: By Product: Primary Cells, Media; By Separation Methods: Explant Method, Enzymatic Degradation; By Cell Type: Animal, Human; By Application) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 - 2030

Published Date : Apr 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Primary Cell Culture market size is expected to be worth around US$ 9.0 billion by 2030, according to a new report by Vision Research Reports.

The global Primary Cell Culture market size was valued at US$ 4.4 billion in 2020 and is anticipated to grow at a CAGR of 21.6% during forecast period 2021 to 2030.

Growth Factors

The market growth is owing to several factors such as advancement in genetic engineering, rising demand for regenerative medicines, and robust funding for cellular therapies development.

In addition, the growing focus on functional biology can be further attributed to the market growth. Several R&D investments for the development of novel solutions have increased the demand for culture medium. For instance, in April 2020, Sumitomo Chemical invested USD 30 million in Conagen a U.S.-based company. The investment was aimed at strengthening its alliance and developing high functional products as well as processes using synthetic biology.

Moreover, the ongoing COVID-19 pandemic has provided an opportunity for researchers to study and understand the new variants of the virus with the application of primary cell culture. The large pool of human cells from various genetic backgrounds and varied health conditions facilitated researchers to conduct experiments for thorough results. Various institutions have shown their support and interest in scientific research to match specialized cell culture media.

Report Highlights

The reagents and supplements segment dominated the market for primary cell culture and accounted for the largest revenue share of 34.0% in 2020. The growth in the segment is owing to its routine application in research and manufacturing involving primary cell culture. Since primary cells are fragile in nature, the reagents and supplements are considered very crucial for their growth.

In addition, the development of innovative products such as growth factors and cytokines is further contributing to the segment growth. For instance, in October 2020, iBio, Inc., a U.S.-based biotechnology company, signed a strategic agreement with Safi Biosolutions, Inc. for the development of growth factors and cytokines using iBio’s FastPharming System.

The primary cells segment is expected to witness the fastest CAGR of 11.8% over the forecast period. This growth can be attributed to the rising identification of primary cells for treating different diseases. For instance, in February 2021, researchers at the Garvan Institute of Medical Research identified a novel bone cell type that may generate new therapeutic targets and approaches for osteoporosis and other skeletal diseases. Hence, such robust research initiatives in the space are expected to significantly boost segment growth.

The enzymatic degradation segment dominated the market for primary cell culture and accounted for the largest revenue share of 33.3% in 2020. The large share of the segment is owing to its high preference over other techniques for separation of primary cells due to the advantages such as less damage to cultures, comparatively fast, and high yield of a representative sample.

In enzymatic degradation, trypsin dominated the market for primary cell culture in terms of revenue share in 2020 owing to its high application for enzymatic disaggregation of tissues. The enzyme has wide application for dissociation of cells from tissues, processing of adhesive cells from flasks, and rapid passaging of large cell suspension.

The mechanical separation segment is expected to witness a lucrative CAGR of 11.7% over the forecast period owing to the advancements in the mechanical separation process. For instance, in October 2020, a group of researchers in France cultured primary skin cells from systemic sclerosis patients by using mechanical extraction combined with immuno-magnetic cell sorting. The study concluded that the technique allowed a purity rate of around 80% for human dermal microvascular endothelial cells as compared to conventional techniques.

The vaccine production segment dominated the market for primary cell culture and held the largest revenue share of 12.2% in 2020. This growth is owing to the increasing use of primary animal cultures for virus production that is later used for producing several vaccines such as measles, and hepatitis B. In addition, this has also led to cost reduction associated with the use of animal models for vaccine testing.

The stem cell therapy segment is expected to witness a lucrative CAGR of 11.9% over the forecast period. The growth of the segment is attributed to the growing attention of scientists over the world for conducting various research projects using stem cells. Research studies using embryonic, induced, and adult stem cells are rapidly changing the way researchers perceive primary cells. In addition, stem cell-based therapies have shown great potential and applications in neurodegenerative diseases, ocular diseases, diabetes, dentistry, and others. Hence, the increasing application of such therapies is further anticipated to drive the market.

The animal cells segment dominated the market for primary cell culture and accounted for the largest revenue share of 58.6% in 2020. The growing applications of animal origin primary cells for vaccine development are major factors fueling the segment growth. Animal-derived primary cultures have been used for the development of vaccines against rabies, polio, measles, chickenpox, and hepatitis B.

In addition, the wide product offering of animal-origin primary cells by companies such as Lonza; Merck KGaA; and Thermo Fisher Scientific, Inc. can be further attributed to the segment growth. These include mouse, rat, rabbit, and monkey-derived fibroblasts; hepatocytes; keratinocytes; and immune, hematopoietic, meningeal, mesangial, and adipose stem cells.

The human cells segment is expected to witness substantial growth over the forecast period. The growth in the segment is majorly due to the rising application of human-derived primary cultures for cancer research. Primary human cancer cells are sourced from a variety of tissue types such as brain, muscle, and connective tissue to facilitate the physiologically relevant study of cancer. These cultures closely resemble the behavior and phenotype of cancer tissues, serving as a valid tool for preclinical and clinical analyses in cancer research.

North America dominated the primary cell culture market and accounted for the largest revenue share of 52.6% in 2020 and is expected to continue this trend over the forecast period. The growth in this region can be attributed to high healthcare expenditure, growing geriatric population, rising incidence of chronic diseases, and supportive government funding. In addition, the increasing focus of market participants for innovating cell culture applications, instrumentation, availability of different types of cells, and their cellular interactions is further contributing to market growth in the region.

Asia Pacific is expected to be the fastest-growing region over the forecast period. The growth is primarily owing to the lower costs associated with stem cell transplantation in the region, thereby contributing to the high demands. In addition, researchers are conducting extensive R&D activities which can be further attributed to the region’s growth. For instance, in March 2020, researchers at China’s Centre for Disease Control (CDC) grew lung airway cells from human tissue culture systems to propagate SARS-CoV-2.

Key Players

  • Thermo Fisher Scientific, Inc.

  • Lonza

  • Merck

  • Corning Incorporated

  • Danaher  

  • PromoCell GmbH

  • ATCC

  • FUJIFILM Irvine Scientific, Inc.

  • Mattek

  • Axol Bioscience Ltd.

Market Segmentation

  • Product Outlook

  • Primary Cells

      • Fat

      • Blood

      • Nerve

      • Bone

      • Endothelial

      • Skin

      • Muscle

      • Stem

      • Others

    • Reagents and Supplements

      • Attachment Solutions

      • Buffers and Salts

      • Freezing Media

      • Sera

      • Growth Factors and Cytokines

      • Other

    • Media

      • Fat Cells Media

      • Blood Cells Media

      • Nerve Cells Media

      • Bone Cells Media

      • Endothelial Cells Media

      • Skin Cells Media

      • Muscle Cells Media

      • Stem Cells Media

      • Others 

  • Separation Methods Outlook

    • Explant Method

    • Enzymatic Degradation

      • Trypsin

      • Collagenase

      • Protease

      • Pronase

      • Dispase

      • Hyaluronidase

      • Neuraminidase

      • Elastase

      • DNase

      • Papain

      • Accutase

      • Others

    • Mechanical Separation

    • Others

  • Cell Type Outlook

    • Animal

    • Human

  • Application Outlook

    • Tissue Culture & Tissue Engineering

    • Vaccine Production

    • Gene Therapy and Regenerative Medicine

    • Toxicity Testing and Drug Screening

    • Cancer Research

    • Model System

    • Virology

    • Prenatal Diagnosis

    • Stem Cell Therapy

    • Others

  • Regional Outlook

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    •  Asia Pacific

      • China

      • Japan

    •  Latin America

      • Brazil

      • Mexico

    •  Middle East & Africa

      • South Africa

The Primary Cell Culture market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Primary Cell Culture market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Primary Cell Culture market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Primary Cell Culture market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Primary Cell Culture market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Primary Cell Culture capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Primary Cell Culture by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Primary Cell Culture market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Primary Cell Culture market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Primary Cell Culture market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Primary Cell Culture industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Primary Cell Culture market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Primary Cell Culture market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Primary Cell Culture market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Primary Cell Culture market. These factors have benefited the growth of the global market for Primary Cell Culture. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Primary Cell Culture. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Primary Cell Culture are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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