Oligonucleotide Synthesis Market Size, Share, Trends, Growth, Production, Consumption, Revenue, Company Analysis and Forecast 2021-2030

Published Date : Feb 2021 | No. of Pages : 250 Pages | Category : Healthcare

The global Oligonucleotide Synthesis market size is expected to be worth around US$ 5.9 billion by 2030, according to a new report by Vision Research Reports.

The global Oligonucleotide Synthesis market size was valued at US$ 2.5 billion in 2020 and is anticipated to grow at a CAGR of 14.4% during forecast period 2021 to 2030.

Growth Factors

Continuous rise in usage of oligonucleotide synthesis across various aspects of human health management, from molecular diagnostics to therapeutics, is spurring revenue growth.

The recent success of oligonucleotide-based drugs in medicine due to increase in number of FDA-approved products is anticipated to boost revenue generation in this market. As of September 2017, there are six approved oligonucleotide therapeutic products.

A substantial number of oligos are under late phase clinical trials targeting various conditions such as cancer, cardiovascular diseases, muscle dystrophies, and ocular disorders. This anticipated regulatory approval for multiple oligonucleotide-based therapies is expected to propel the market.

Marketing approaches implemented in this market include direct selling and selling via distributors in specific countries. The market is expected to benefit from the constant growth of genomics and gene editing markets, as advancement in genetic tools would simplify the synthesis of oligonucleotides.

Report Highlights

Introduction of novel and robust synthesizers that enable rapid and large-scale production of long oligonucleotide sequences is driving the segment. However, there has been an increase in uptake of contract manufacturing services and consulting owing to various advantages associated with contract service providers, such as improved efficiency, cost-effective services, and rapid development of products. This is anticipated to foster the growth of the services segment.

The presence of a wide array of reagents for deacetylation/deblocking, oxidation, cleavage, purification/desalting, labeling, and modification of oligonucleotides has significantly contributed to the dominant share of this segment in 2020. The segment is also fueled by the need for specific reagents at each step of synthesis and high cost.

PCR primers are widely used in drug development for target screening and identification. The presence of a robust pipeline of oligonucleotides-based therapeutics, including antisense therapeutics, DNA vaccines, and anti-viral agents, in various phases of clinical development, has allowed PCR primers to enjoy the largest revenue share in the oligonucleotide synthesis market.

An increase in focus on targeted gene therapies has revolutionized the treatment of incurable conditions caused by genetic mutations. An increase in demand for sequencing applications by clinical, diagnostic, academic, and drug development is witnessed by manufacturers.

Pharmaceutical industries and biotechnology companies are focused on seeking alternative approaches for disease treatment. As a result, these companies are making significant use of oligonucleotides, as it offers an effective mode of action for the treatment of various indications at comparatively lower development costs.

Furthermore, oligonucleotides play a vital role in overcoming challenges about the efficient route of drug administration. This, in turn, is projected to increase the manufacturing of oligonucleotide therapeutics, thereby enhancing the share of pharmaceutical and biotechnology companies in the global market.

Government and private entities are investing in the development of academic and research infrastructure in emerging economies. This factor is expected to positively boost oligonucleotide adoption in academic research institutes. The surge in genomic research projects conducted by academic research institutes has enabled this segment to account for the dominant share in the market. Moreover, collaboration among major players and universities for the development of novel approaches to curing chronic conditions through genetic medicine is expected to contribute to the growth of this segment.

The presence of innovators and key players in the U.S. has resulted in higher penetration of products in the market. This has allowed North America to account for a significant revenue share in 2020. Furthermore, the strong foothold of North America in genomics, proteomics, oncology, diagnostic screening, and drug discovery has significantly contributed to maintaining its large share.

Key Players

Thermo Fisher Scientific, Inc.; Merck - Co., Inc.; GE Healthcare Dharmacon Inc.; Agilent Technologies; Bio-synthesis; Kaneka Eurogentec S.A.; Integrated DNA Technologies, Inc.; BioAutomation; and LGC Biosearch Technologies. 

Market Segmentation

  • Product Outlook (

    • Oligonucleotides

      • Oligonucleotides, By Product Type

        • Column-based Oligos

        • Array-based Oligos

      • Oligonucleotides, By Nucleic Acid Type

        • DNA

        • RNA

    • Equipment

    • Reagents

    • Services

      • Oligo Synthesis

        • 25 nmol

        • 50 nmol

        • 200 nmol

        • 1000 nmol

        • 10,000 nmol

      • Purification

      • Modification

  • Application Outlook 

    • PCR Primers

    • PCR Assays and Panels

    • Sequencing

    • DNA Microarrays

    • Fluorescence In Situ Hybridization (FISH)

    • Antisense Oligonucleotides

    • Other Applications

  • End-use Outlook 

    • Academic Research Institutes

    • Diagnostic Laboratories

    • Pharmaceutical - Biotechnology Companies

  • Regional Outlook 

  •  

    • North America

      • The U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • Japan

      • China

    • Latin America

      • Brazil

    • The Middle East and Africa (MEA)

      • South Africa

The Oligonucleotide Synthesis market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Oligonucleotide Synthesis market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Oligonucleotide Synthesis market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Oligonucleotide Synthesis market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Oligonucleotide Synthesis market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

In terms of production side, this report researches the Oligonucleotide Synthesis capacity, production, value, ex-factory price, growth rate, market share for major manufacturers, regions (or countries) and type.

In terms of consumption side, this report focuses on the consumption of Oligonucleotide Synthesis by regions (countries) and application.

Buyers of the report will have access to verified market figures, including global market size in terms of revenue and volume. As part of production analysis, the authors of the report have provided reliable estimations and calculations for global revenue and volume by Type segment of the global Oligonucleotide Synthesis market. These figures have been provided in terms of both revenue and volume for the period 2017 to 2030. Additionally, the report provides accurate figures for production by region in terms of revenue as well as volume for the same period. The report also includes production capacity statistics for the same period.

With regard to production bases and technologies, the research in this report covers the production time, base distribution, technical parameters, research and development trends, technology sources, and sources of raw materials of major Oligonucleotide Synthesis market companies.

Regarding the analysis of the industry chain, the research of this report covers the raw materials and equipment of Oligonucleotide Synthesis market upstream, downstream customers, marketing channels, industry development trends and investment strategy recommendations. The more specific analysis also includes the main application areas of market and consumption, major regions and Consumption, major Chinese producers, distributors, raw material suppliers, equipment providers and their contact information, industry chain relationship analysis.

The research in this report also includes product parameters, production process, cost structure, and data information classified by region, technology and application. Finally, the paper model new project SWOT analysis and investment feasibility study of the case model.

Overall, this is an in-depth research report specifically for the Oligonucleotide Synthesis industry. The research center uses an objective and fair way to conduct an in-depth analysis of the development trend of the industry, providing support and evidence for customer competition analysis, development planning, and investment decision-making. In the course of operation, the project has received support and assistance from technicians and marketing personnel in various links of the industry chain.

The Oligonucleotide Synthesis market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies’ focus related to Oligonucleotide Synthesis market.

Prominent players in the market are predicted to face tough competition from the new entrants. However, some of the key players are targeting to acquire the startup companies in order to maintain their dominance in the global market. For a detailed analysis of key companies, their strengths, weaknesses, threats, and opportunities are measured in the report by using industry-standard tools such as the SWOT analysis. Regional coverage of key companies is covered in the report to measure their dominance. Key manufacturers of Oligonucleotide Synthesis market are focusing on introducing new products to meet the needs of the patrons. The feasibility of new products is also measured by using industry-standard tools.

Key companies are increasing their investments in research and development activities for the discovery of new products. There has also been a rise in the government funding for the introduction of new Oligonucleotide Synthesis market. These factors have benefited the growth of the global market for Oligonucleotide Synthesis. Going forward, key companies are predicted to benefit from the new product launches and the adoption of technological advancements. Technical advancements have benefited many industries and the global industry is not an exception.

New product launches and the expansion of already existing business are predicted to benefit the key players in maintaining their dominance in the global market for Oligonucleotide Synthesis. The global market is segmented on the basis of region, application, en-users and product type. Based on region, the market is divided into North America, Europe, Asia-Pacific, Latin America and Middle East and Africa (MEA).

In this study, the years considered to estimate the market size of Oligonucleotide Synthesis are as follows:

  • Historic Year: 2017-2020
  • Base Year: 2021
  • Forecast Year 2021 to 2030

Reasons to Purchase this Report:

- Market segmentation analysis including qualitative and quantitative research incorporating the impact of economic and policy aspects
- Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market.
- Market value USD Million and volume Units Million data for each segment and sub-segment
- Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
- Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players

Research Methodology:

In-depth interviews and discussions were conducted with several key market participants and opinion leaders to compile the research report.

This research study involved the extensive usage of both primary and secondary data sources. The research process involved the study of various factors affecting the industry, including the government policy, market environment, competitive landscape, historical data, present trends in the market, technological innovation, upcoming technologies and the technical progress in related industry, and market risks, opportunities, market barriers and challenges. The following illustrative figure shows the market research methodology applied in this report.

Market Size Estimation

Top-down and bottom-up approaches are used to estimate and validate the global market size for company, regional division, product type and application (end users).

The market estimations in this report are based on the selling price (excluding any discounts provided by the manufacturer, distributor, wholesaler or traders). Market share analysis, assigned to each of the segments and regions are achieved through product utilization rate and average selling price.

Major manufacturers & their revenues, percentage splits, market shares, growth rates and breakdowns of the product markets are determined through secondary sources and verified through the primary sources.

All possible factors that influence the markets included in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. The market size for top-level markets and sub-segments is normalized, and the effect of inflation, economic downturns, and regulatory & policy changes or others factors are accounted for in the market forecast. This data is combined and added with detailed inputs and analysis from Vision Research Reports and presented in this report.

Market Breakdown and Data Triangulation

After complete market engineering with calculations for market statistics; market size estimations; market forecasting; market breakdown; and data triangulation. Extensive primary research was conducted to gather information and verify and validate the critical numbers arrived at. In the complete market engineering process, both top-down and bottom-up approaches were extensively used, along with several data triangulation methods, to perform market estimation and market forecasting for the overall market segments and sub-segments listed in this report.

Secondary Sources

Secondary Sources occupies approximately 25% of data sources, such as press releases, annual reports, Non-Profit organizations, industry associations, governmental agencies and customs data, and so on. This research study includes secondary sources; directories; databases such as Bloomberg Business, Wind Info, Hoovers, Factiva (Dow Jones & Company), TRADING ECONOMICS, and avention; Investing News Network; statista; Federal Reserve Economic Data; annual reports; investor presentations; and SEC filings of companies.

Primary Sources

 In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include product manufacturers (and their competitors), opinion leaders, industry experts, research institutions, distributors, dealer and traders, as well as the raw materials suppliers and producers, etc.

The primary sources from the demand side include industry experts such as business leaders, marketing and sales directors, technology and innovation directors, supply chain executive, end users (product buyers), and related key executives from various key companies and organizations operating in the global market.

The study objectives of this report are:

  • To analyze and study the global market capacity, production, value, consumption, status (2017-2020) and forecast (2021-2030);
  • Focuses on the key manufacturers, to study the capacity, production, value, market share and development plans in future.
  • Comprehensive company profiles covering the product offerings, key financial information, recent developments, SWOT analysis, and strategies employed by the major market players
  • To define, describe and forecast the market by type, application and region.
  • To analyze the global and key regions market potential and advantage, opportunity and challenge, restraints and risks.
  • To identify significant trends and factors driving or inhibiting the market growth.
  • To analyze the opportunities in the market for stakeholders by identifying the high growth segments.
  • To strategically analyze each submarket with respect to individual growth trend and their contribution to the market
  • To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market
  • To strategically profile the key players and comprehensively analyze their growth strategies.

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